Results 121 to 130 of about 10,258 (173)

Discovery and preclinical evaluation of monoclonal antibodies and bispecific engagers targeting the NKG2A inhibitory receptor. [PDF]

Sci Adv
Shin S, Kim YJ, Macatangay BJC, Cyktor JC, Hines MG, Sun ZY, Chen K, Mellors JW, Dimitrov DS, Li W, Baek DS.   +10 more
europepmc   +1 more source

Latent cytomegalovirus disrupts innate NK cell responses to P. falciparum and impairs parasite control in first infection in adults. [PDF]

PLoS Pathog
Mukhiya R, Loughland JR, Dooley NL, Pava Z, Oyong DA, Andrew DW, Hamelink J, Berry K, McCarthy JS, Barber BE, Lopez JA, Engwerda CR, Boyle MJ.   +12 more
europepmc   +1 more source

In Search of Adaptive-Like Features of NK Cells Co-Expressing NKG2C and NKG2A. [PDF]

Immune Netw
Alekseeva NA, Ustiuzhanina MO, Vavilova JD, Streltsova MA, Boyko AA, Sapozhnikov AM, Kovalenko EI.   +6 more
europepmc   +1 more source

The bacteroidal metabolite O-LysoPE facilitates hepatocyte-mediated immunosuppression in autoimmune hepatitis. [PDF]

Nat Commun
Xu M, Luo K, Zhou Z, Li J, Zhang S, Kong L, Jiang L, Zhang Y, Li Y, Xiao F, Zhu C, Xu Q, Yi H, Wu X.   +13 more
europepmc   +1 more source

Sustained mucosal delivery of SAMT-247 via an intravaginal ring reduces the risk of SIV_mac251 acquisition in vaccinated macaques. [PDF]

Cell Rep Med
Rahman MA, Woode EK, Moss JA, Bissa M, Gunawardana M, Gutowska A, Schifanella L, Silva de Castro I, Brown S, Stamos JD, Sarkis S, Robello M, Castonguay AE, Butkyavichene I, Pise-Masison CA, Choo-Wosoba H, Doster M, Alilin AN, Killoran KE, Kramer J, Breed MW, Cardozo T, Appella DH, Baum MM, Franchini G.   +24 more
europepmc   +1 more source

Extraordinary diversity of antiviral immune-related gene families across 38 bat species. [PDF]

BMC Biol
Liu G, Ren Y, Zhou S, Hua Q, Chen P, Zhang H, Liu Z.   +6 more
europepmc   +1 more source

Outsmarting NK surveillance: engineering stealth CAR T cells. [PDF]

Blood Adv
Nunez Cortes AK, Basar R.
europepmc   +1 more source

High-Dimensional Immune Profiling Identifies Circulating NKT-Like Cells Associated With Severity Outcome in Acute Pancreatitis at Disease Onset. [PDF]

Immunology
González de Castro C, Ruiz Rebollo ML, Cal-Sabater P, Arribas-Rodríguez E, Martín-Muñoz Á, Gonzalez Del Hierro A, Perez Mazzali M, Matesanz-Isabel J, Gonzalo-Benito H, Cuesta-Sancho S, Bernardo D.   +10 more
europepmc   +1 more source

Structural basis for NKG2A/CD94 recognition of HLA-E [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2008
The NKG2x/CD94 (x = A, C, E) natural killer-cell receptors perform an important role in immunosurveillance by binding to HLA-E complexes that exclusively present peptides derived from MHC class I leader sequences, thereby monitoring MHC class I expression.
Roland K Strong
exaly   +3 more sources

Intratumoral co-injection of NK cells and NKG2A-neutralizing monoclonal antibodies

EMBO Molecular Medicine, 2023
Abstract NK‐cell reactivity against cancer is conceivably suppressed in the tumor microenvironment by the interaction of the inhibitory receptor NKG2A with the non‐classical MHC‐I molecules HLA‐E in humans or Qa‐1 b in mice.
Carmen Molina, Assunta Cirella, Ignacio Melero   +2 more
exaly   +4 more sources