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The predictive value of NKG2C+NK cells and LILRB1+NK cells in recurrent spontaneous abortion
American Journal of Reproductive Immunology, 2022AbstractProblemThe maternal‐fetal immune abnormalities can result in recurrent spontaneous abortion (RSA). The role of NKG2C+ and LILRB1+ pNK subsets in predicting pregnancy loss is uncertain.Method of StudyIn this study, we aimed to compare the percentage of CD3−CD56+ NK cells, NKG2C+ NK cells, and LILRB1+ NK cells in peripheral blood between healthy ...
Yue Hou +5 more
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Characterization of copy number variations (CNV) in the NKG2C receptor gene
Human Immunology, 2015The cytolytic function of natural killer (NK) cells is controlled by a balance of activatory and inhibitory signals transduced by specific NK-cell receptors. NKG2 family is one of the superfamilies of these receptor genes located on chromosome 12 in the NKC gene complex.
Kai Cao +5 more
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Blood
Abstract Background: Natural Killer (NK) cells are critical components of the innate immune system, providing rapid responses against virally infected and tumor cells. A specialized subset of these cells, characterized by the expression of the activating receptor NKG2C, plays an essential role
Mohamed Khalil, Subramaniam Malarkannan
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Abstract Background: Natural Killer (NK) cells are critical components of the innate immune system, providing rapid responses against virally infected and tumor cells. A specialized subset of these cells, characterized by the expression of the activating receptor NKG2C, plays an essential role
Mohamed Khalil, Subramaniam Malarkannan
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Expansion of CD94/NKG2C+ NK cells in response to human cytomegalovirus-infected fibroblasts
Blood, 2006CD94/NKG2C+ natural killer (NK) cells are increased in healthy individuals infected with human cytomegalovirus (HCMV), suggesting that HCMV infection may shape the NK cell receptor repertoire. To address this question, we analyzed the distribution of NK cell subsets in peripheral blood lymphocytes (PBLs) cocultured with HCMV-infected fibroblasts.
Mónica, Gumá +6 more
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The Distribution of Anti-NKG2A and NKG2C Positive Cells in Lichen Palnopilaris
Journal of Clinical & Experimental Dermatology Research, 2013Background: Lichen planopilaris (LPP) is a rare alopecia disorder. The histopathological features of LPP may resemble discoid lupus erythematosus (DLE). However, LPP usually lacks interfollicular inflammation, which differentiates it from DLE. Methods: Skin biopsies were taken from subjects with early-stage LPP and DLE. The biopsies were evaluated for
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The Journal of Physical Chemistry B, 2013
In this work, we have investigated in details the origin of the assembly of the DAP12 dimer with only one NKG2C in the activating immunoreceptor complex from thew two aspects of electronic properties and dynamic structures by performing density functional theory (DFT) calculations and molecular dynamics (MD) simulations.
Hui, Sun +4 more
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In this work, we have investigated in details the origin of the assembly of the DAP12 dimer with only one NKG2C in the activating immunoreceptor complex from thew two aspects of electronic properties and dynamic structures by performing density functional theory (DFT) calculations and molecular dynamics (MD) simulations.
Hui, Sun +4 more
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Cytotoxic NKG2C+ CD4 T cells target oligodenfrocytes in Multiple Sclerosis
2013La sclérose en plaques (SEP) est caractérisée par l'infiltration de cellules immunes au sein du système nerveux central (SNC). Les mécanismes par lesquels ces cellules contribuent à la formation des lésions typiques de cette pathologie restent à élucider. Les cellules T CD4 jouent un rôle important dans l'inflammation observée en SEP.
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Complete genomic characterization of a new KLRC2 allele, NKG2C*03
Hla, 2021CARLOS Vilches +2 more
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The predictive value of NKG2C+NK cells and LILRB1+NK cells in recurrent spontaneous abortion
American Journal of Reproductive Immunology, 2023Chong Qiao
exaly