Results 161 to 170 of about 5,157 (213)
MendelR: A One‐Stop R Toolkit for Mendelian Randomization Analysis
ABSTRACT MendelR is a fully automated R package specifically developed for Mendelian randomization (MR) studies, designed to address the technical challenges of causal inference in biomedical research. As a powerful causal inference method, Mendelian randomization can effectively reduce confounding bias in observational studies.
Xiaohong Ke +4 more
wiley +1 more source
Editorial: NKT Cells in Cancer Immunotherapy [PDF]
Tonya J. Webb +3 more
openaire +3 more sources
Single‐walled carbon nanotubes (SWCNTs) are versatile optical nanosensors that can be imaged at the single‐sensor level to map biological processes. To translate such imaging into calibrated measurements, sensor recovery under repeated analyte exposures must be analyzed.
Geffen Rosenberg, Gili Bisker
wiley +1 more source
Magnetic fields modulate macrophage‐cancer crosstalk through the STING‐TRPC1 axis. Exposure reprograms macrophages toward the anti‐cancer phenotype. Exposing cancer cells modulates cancer secretome to promote polarization and selective recruitment of M1‐tumoricidal macrophages, enhancing cancer immunogenicity.
Viresh Krishnan Sukumar +7 more
wiley +1 more source
T‐Cell Biology in the Female Reproductive Tract: Relevance to HIV Infection
ABSTRACT Worldwide, most HIV infections occur across a mucosal surface during sexual contact, with women accounting for nearly half of reported new HIV infections across the globe in 2024. Most new infections in women and girls are believed to involve transmission across mucosal surfaces of the lower reproductive tract, which includes the vagina and ...
Barbara L. Shacklett +2 more
wiley +1 more source
Fel d 1‐Expressing Plant‐Derived Bioparticle: A Novel Treatment for Cat Allergy
This study investigates the allergenicity and immunogenicity profile of a novel plant‐derived Fel d 1 bioparticle (eBP). Fel d 1 eBP promotes immune tolerance by redirecting allergic Th2 responses toward Th1 and IL‐10–producing regulatory pathways, including Bregs.
Janice A. Layhadi +16 more
wiley +1 more source
Development and function of NKT cell subsets in humans
NKT cells are a type of white blood cell that help to control the function of the immune system. Many studies have reported an association between low NKT cell levels and increased rates of cancer and autoimmune diseases such as type 1 diabetes (T1D ...
core
A Case for Anti‐IgE Vaccination
ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff +3 more
wiley +1 more source
Significance Statement Euglena gracilis is an early diverging photosynthetic organism with a unique mosaic photosynthetic apparatus. Biochemical and spectroscopic analysis reveals a kinetically slower photosystem I sharing excitation energy with photosystem II in the absence of strict photosystem segregation.
Parveen Akhtar +6 more
wiley +1 more source
Abstract Background Umbilical cord blood (UCB) is a rich source of hematopoietic stem and progenitor cells for regenerative medicine. This study characterized the cellular composition of UCB from twin pregnancies to identify blood type concordance (BTC)‐related differences.
Van‐Tinh Nguyen +8 more
wiley +1 more source

