Multiple Sclerosis and Viruses: « Liaisons Dangereuses »
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Samanta Plavina +11 more
wiley +1 more source
SAP expression in invariant NKT cells is required for cognate help to support B-cell responses
One of the manifestations of X-linked lymphoproliferative disease (XLP) is progressive agammaglobulinemia, caused by the absence of a functional signaling lymphocyte activation molecule (SLAM)-associated protein (SAP) in T, invariant natural killer T ...
Keszei, Marton +12 more
core +1 more source
First-in-human clinical trial of the NKT cell-stimulatory glycolipid OCH in multiple sclerosis. [PDF]
Sato W +13 more
europepmc +1 more source
Abstract A domestic shorthair cat was presented with lethargy and inappetence. Abdominal ultrasound revealed a large jejunal mural mass with diffuse wall thickening without loss of wall layering, severe jejunal lymphadenopathy, and moderate peritoneal effusion.
Riley Aronson +4 more
wiley +1 more source
In this study, we revealed the disturbed metabolic status of circulating and tumour‐infiltrating CD4+ and CD8+ T cells in melanoma patients through targeted metabolomic and lipidomic (on sorted subsets) and at single cell level using the SCENITH method.
Hugo Brouque +11 more
wiley +1 more source
A liposomal carbohydrate vaccine, adjuvanted with an NKT cell agonist, induces rapid and enhanced immune responses and antibody class switching. [PDF]
Jia JX +6 more
europepmc +1 more source
Myo1g Mediates NKR‐P1C Expression in Primary Mouse NK Cells and Participates in Cytotoxicity
In this study we analysed the participation of Myosin 1g in the development and functions of murine natural killer (NK) cells; we found that Myosin 1g is expressed in murine‐activated primary NK cells from the spleen. Additionally, in the absence of Myosin 1g, correlates with a reduced expression of NKR‐P1C but not of CD49b or NKp46.
Héctor Romero‐Ramírez +3 more
wiley +1 more source
Inbred Strain Characteristics Impact the NKT Cell Repertoire. [PDF]
Shissler SC +4 more
europepmc +1 more source
Identification and Isolation of Type II NKT Cell Subsets in Human Blood and Liver. [PDF]
Yang Zhou J +5 more
europepmc +1 more source
Potent NKT cell ligands overcome SARS-CoV-2 immune evasion to mitigate viral pathogenesis in mouse models. [PDF]
Lu H +13 more
europepmc +1 more source

