Results 141 to 150 of about 5,262,931 (244)

Hyperspectral tomographic diffractive microscopy: Development and applications

Journal of Microscopy, EarlyView.
Abstract Tomographic Diffractive Microscopy (TDM) provides label‐free three‐dimensional imaging of transparent samples with resolution surpassing confocal limits. At IRIMAS, successive instrumental developments since 2009 have enhanced TDM capabilities through transmission, reflection, isotropic, polarisation‐sensitive, and dual‐view configurations ...
Leonardo Pestana Legori, Carlos Alberto Chacón Ávila, Matthieu Debailleul, Nicolas Verrier, Olivier Haeberlé   +4 more
wiley   +1 more source

Identification of novel self lipids, GlcCer and GalCer, as CD1d-restricted ligands for type II NKT cells

, 2011
NKT cells make up a potent immunomodulating subset of T lymphocytes that recognizes self-lipids presented by CD1d molecules. So far, the identity of most self-lipids presented by CD1d underlying the autoreactivity of NKT cells are unknown. In this study,
Löfbom, Linda,, Teneberg, Susann,, Cardell, Susanna,, Rhost, Sara,, Blomqvist, Maria K.,, Månsson, Jan-Eric,   +5 more
core  

Gal-3 regulates the capacity of dendritic cells to promote NKT-cell-induced liver injury

, 2014
Galectin-3 (Gal-3), an endogenous lectin, exhibits ro- and anti-inflammatory effects in various disease conditions. In order to explore the role of Gal-3 in KT-cell-dependent pathology, we induced hepatitis in C57BL/6WT and al-3-deficient mice by using ...
Nilsson U., Vladislav Volarevic, Sanja Bojic, Nebojsa Arsenijevic, Markovic, Bojana Simovic, Besra, Gurdyal S., Besra, Gurdyal, Ulf Nilsson, Vladimir Trajkovic, Stojanovic, Maja, Gurdyal S. Besra, Bojana Simovic Markovic, Simovic Markovic, Bojana, Miodrag L. Lukic, Bojic, Sanja, Trajkovic, Vladimir, Maja Stojanovic, Verica Paunovic, Arsenijevic, Nebojsa, Paunovic, Verica, Besra, Gurdyal S; id_orcid, Lukic, Miodrag L, Nilsson, Ulf,, Lukic, Miodrag L., Volarevic, Vladislav, Hakon Leffler, Nilsson, Ulf, Lukic, Miodrag, Lund University., Leffler, Hakon, Leffler, Hakon,   +30 more
core   +1 more source

Intratumoural administration of an NKT cell agonist with CpG promotes NKT cell infiltration associated with an enhanced antitumour response and abscopal effect. [PDF]

Oncoimmunology, 2022
Prasit KK, Ferrer-Font L, Burn OK, Anderson RJ, Compton BJ, Schmidt AJ, Mayer JU, Chen CJ, Dasyam N, Ritchie DS, Godfrey DI, Mattarollo SR, Dundar PR, Painter GF, Hermans IF.   +14 more
europepmc   +1 more source

A validated deep learning workflow for 3D quantification of amyloid plaques in cleared mouse brain

Journal of Microscopy, EarlyView.
Abstract Accurate quantification of amyloid plaque pathology is essential for understanding Alzheimer's disease (AD) progression and evaluating therapeutic interventions. Yet, conventional histology relies on sampling thin tissue sections and therefore incompletely captures three‐dimensional (3D) plaque distributions, introducing bias and limiting ...
Veronika Valova, Louise Cole, Neftali Flores Rodriguez, Filip Braet, Daniel M. Johnstone, Richard Harwood   +5 more
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

T cell, NK and NKT cell populations in active RA, Remission RA and healthy controls.

, 2013
Graph illustrating T cell, NK and NKT cell populations in healthy controls (N = 15) (▴), patients with active RA (n = 18) (○) and patients in remission following TNF inhibitor (n = 15 ...
Elizabeth J. Ryan (339092), Ursula Fearon (8519), Oliver FitzGerald (26005), Douglas J. Veale (339506), Barry Bresnihan (26006), Ceara E. Walsh (339504), Cliona O’Farrelly (339505), Lucy Golden-Mason (242863)   +7 more
core   +1 more source

IFN-γ-dependent regulation of intestinal epithelial homeostasis by NKT cells

Cell Reports
Summary: Intestinal homeostasis is maintained through the combined functions of epithelial and immune cells that collaborate to preserve the integrity of the intestinal barrier. However, the mechanisms by which immune cell populations regulate intestinal
Marta Lebrusant-Fernandez, Tom ap Rees, Rebeca Jimeno, Nikolaos Angelis, Joseph C. Ng, Franca Fraternali, Vivian S.W. Li, Patricia Barral   +7 more
doaj   +1 more source

Safety and Feasibility of Infusing Ex Vivo Expanded Allogeneic Canine Natural Killer Cells for the Treatment of Metastatic Solid Tumours

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Companion canines need advances in therapeutic options for solid tumour malignancies. Natural killer (NK) cell infusions offer a promising treatment modality in canines with solid tumours. Autologous natural killer products are limited by dysfunctional immunity and a manufacturing process that delays care whereas allogeneic NK cells offer the ...
Allison M. Weisnicht, Fernanda Szewc, Monica Moonkyung Cho, Han‐Yun Hannah Cheng, Swetha Ganesh, Lauren Mahoney, Kathryn Fox, Portia R. Smith, Mallery Olsen, Rebecca M. Richards, David M. Vail, Christian M. Capitini   +11 more
wiley   +1 more source

Cullin 3-Mediated Regulation of Intracellular Iron Homeostasis Promotes Thymic Invariant NKT Cell Maturation. [PDF]

Immunohorizons, 2023
Yarosz EL, Kumar A, Singer JD, Chang CH.
europepmc   +1 more source