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Roles of NKT cells in cancer immunotherapy
Archives of Pharmacal Research, 2019Cancer immunotherapy has emerged as an effective therapeutic strategy to treat cancer. Among diverse immune populations, invariant natural killer T (iNKT) cells have shown potent antitumor activity by linking innate and adaptive immune systems. Upon activation by lipid antigens on CD1d molecules, iNKT cells rapidly produce various cytokines and trigger
Eun-Ah, Bae +4 more
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Liver invariant NKT cells and listeriosis
Microbes and Infection, 2008The invariant (i) NKT cells represent unique T lymphocytes expressing TCRValpha14. Although iNKT cells have been regarded as T lymphocytes expressing NK1.1, they do not consistently express this marker. NK1.1 allows recognition of "missing-self" and thus controls inhibition/activation of iNKT cells.
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Thymic Development of Unconventional T Cells: How NKT Cells, MAIT Cells and γδ T Cells Emerge
Nature Reviews Immunology, 2020Daniel G Pellicci, Hui-Fern Koay
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The Regulatory Role of Vα14 NKT Cells in Innate and Acquired Immune Response
Annual Review of Immunology, 2003Masaru Taniguchi +2 more
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Initiation of Antiviral B Cell Immunity Relies on Innate Signals From Spatially Positioned NKT Cells
Cell, 2018Dan H. Barouch +2 more
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