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Development and selection of NKT cells
Current Opinion in Immunology, 2002NKT cells utilize a restricted alphabeta TCR repertoire that recognizes glycolipids in association with CD1d. The recent development of fluorescent CD1d tetramers loaded with the synthetic glycolipid alpha-galactosyl-ceramide has led to a clearer definition of NKT-cell subsets as well as important insights into their developmental origin.
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2016
CD1d-restricted invariant natural killer T (NKT) cells are a specialized innate lymphocyte subset that recognizes a glycolipid antigen via the invariant T-cell receptor. Ligand-activated NKT cells display direct antitumor activities against various tumors.
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CD1d-restricted invariant natural killer T (NKT) cells are a specialized innate lymphocyte subset that recognizes a glycolipid antigen via the invariant T-cell receptor. Ligand-activated NKT cells display direct antitumor activities against various tumors.
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Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells
Cell, 2018Mauro Gaya +2 more
exaly
Regulatory T cells induce CD4− NKT cell anergy and suppress NKT cell cytotoxic function
Cancer Immunology, Immunotherapy, 2019Daiju Sakurai +2 more
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A new mouse strain for the analysis of invariant NKT cell function
Nature Immunology, 2015Shilpi Chandra +2 more
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NKT Cell Subsets Mediate Differential Proatherogenic Effects in ApoE −/− Mice
Arteriosclerosis, Thrombosis, and Vascular Biology, 2009Gurdyal Besra, Alex Bobik
exaly
Intrathymic NKT cell development is blocked by the presence of α-galactosylceramide
European Journal of Immunology, 2003Daniel G Pellicci +2 more
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