Results 201 to 210 of about 30,886 (233)
Some of the next articles are maybe not open access.
Blood, 2009
Abstract In this issue of Blood, Swann and colleagues show that type I NKT cells mediate protection against tumor development in p53-deficient mice.
Madhav V, Dhodapkar, Natalia, Neparidze
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Abstract In this issue of Blood, Swann and colleagues show that type I NKT cells mediate protection against tumor development in p53-deficient mice.
Madhav V, Dhodapkar, Natalia, Neparidze
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Microbes and Infection, 2003
Natural killer T (NKT) cells are a subset of lymphocytes that express a semi-invariant T cell receptor (TCR) that recognizes glycolipids presented by the non-polymorphic MHC class I-like molecule CD1d. NKT cells regulate a wide variety of immune functions against autoantigens and pathogens.
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Natural killer T (NKT) cells are a subset of lymphocytes that express a semi-invariant T cell receptor (TCR) that recognizes glycolipids presented by the non-polymorphic MHC class I-like molecule CD1d. NKT cells regulate a wide variety of immune functions against autoantigens and pathogens.
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Working with NKT cells — pitfalls and practicalities
Current Opinion in Immunology, 2005Our understanding of NKT cells has been rapidly advancing over recent years, with many research groups studying how these cells behave and how they can be manipulated to prevent disease. Although good progress has been made, a difficulty is the lack of a clear consensus about how to assay, or even identify, NKT cells. The different approaches have been
Berzins, Stuart P. +2 more
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Retroviral Transduction of NKT Hybridoma Cells
2021Natural killer T (NKT) cells have been shown to bridge innate and adaptive immunity. However, the rare population and hard-to-transfect of primary NKT cells slow down our understanding of cellular and molecular mechanisms of NKT development and function.
Ke, Wang, Rong, Jin, Qing, Ge
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Role of NKT Cells in the Digestive System. III. Role of NKT cells in intestinal immunity
American Journal of Physiology-Gastrointestinal and Liver Physiology, 2007Natural killer T (NKT) cells are a small subset of unconventional T cells that recognize lipid antigens presented by the nonclassical major histocompatibility complex (MHC) class I molecule CD1d. NKT cells are involved in the host response to a variety of microbial pathogens and likely commensals. In the intestine, invariant and noninvariant NKT cells
Zeissig, S +4 more
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T Cells and NKT Cells in the Pathogenesis of Asthma
Annual Review of Medicine, 2008Asthma is an immunological disease with multiple inflammatory and clinical phenotypes, characterized by symptoms of wheezing, shortness of breath, and coughing due to airway hyperreactivity (AHR) and reversible airway obstruction. In allergic asthma, the most common form of asthma, airway inflammation is mediated by adaptive immune recognition of ...
Everett H, Meyer +2 more
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CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy
Clinical Reviews in Allergy & ImmunologyNKT cells, unique lymphocytes bridging innate and adaptive immunity, offer significant potential for managing inflammatory disorders like asthma. Activating iNKT induces increasing IFN-γ, TGF-β, IL-2, and IL-10 potentially suppressing allergic asthma.
Mohadeseh Mohammad, Taheri +3 more
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Roles of NKT cells in cancer immunotherapy
Archives of Pharmacal Research, 2019Cancer immunotherapy has emerged as an effective therapeutic strategy to treat cancer. Among diverse immune populations, invariant natural killer T (iNKT) cells have shown potent antitumor activity by linking innate and adaptive immune systems. Upon activation by lipid antigens on CD1d molecules, iNKT cells rapidly produce various cytokines and trigger
Eun-Ah, Bae +4 more
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NKT Cell Responses to Glycolipid Activation
2009NKT cells are a distinct lineage of T lymphocytes that are usually identified by the co-expression of the semi-invariant CD1d-restricted alphabeta TCR and the NK1.1 allelic marker of NK lineage receptors in the C57BL/6 mice and related strains. NKT cells can be subdivided based on CD4/CD8 expression and on tissue of origin.
Josianne Nitcheu, Tefit +2 more
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Liver invariant NKT cells and listeriosis
Microbes and Infection, 2008The invariant (i) NKT cells represent unique T lymphocytes expressing TCRValpha14. Although iNKT cells have been regarded as T lymphocytes expressing NK1.1, they do not consistently express this marker. NK1.1 allows recognition of "missing-self" and thus controls inhibition/activation of iNKT cells.
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