Invariant NKT cells are more abundant in peanut-allergic adults and a subset of CD8+ iNKT cells are depleted after peanut oil exposure. [PDF]
Hopkins GV +3 more
europepmc +1 more source
Magnetic fields modulate macrophage‐cancer crosstalk through the STING‐TRPC1 axis. Exposure reprograms macrophages toward the anti‐cancer phenotype. Exposing cancer cells modulates cancer secretome to promote polarization and selective recruitment of M1‐tumoricidal macrophages, enhancing cancer immunogenicity.
Viresh Krishnan Sukumar +7 more
wiley +1 more source
Diversity of Circulating NKT Cells in Defense against Carbapenem-Resistant Klebsiella Pneumoniae Infection. [PDF]
Wang Y +12 more
europepmc +1 more source
T‐Cell Biology in the Female Reproductive Tract: Relevance to HIV Infection
ABSTRACT Worldwide, most HIV infections occur across a mucosal surface during sexual contact, with women accounting for nearly half of reported new HIV infections across the globe in 2024. Most new infections in women and girls are believed to involve transmission across mucosal surfaces of the lower reproductive tract, which includes the vagina and ...
Barbara L. Shacklett +2 more
wiley +1 more source
Targeting triple-negative breast cancer using cord-blood CD34⁺ HSPC-derived mesothelin-specific CAR-NKT cells with potent antitumor activity. [PDF]
Li YR +13 more
europepmc +1 more source
Fel d 1‐Expressing Plant‐Derived Bioparticle: A Novel Treatment for Cat Allergy
This study investigates the allergenicity and immunogenicity profile of a novel plant‐derived Fel d 1 bioparticle (eBP). Fel d 1 eBP promotes immune tolerance by redirecting allergic Th2 responses toward Th1 and IL‐10–producing regulatory pathways, including Bregs.
Janice A. Layhadi +16 more
wiley +1 more source
Protocol for assessing pharmacokinetics and pharmacodynamics of human CAR-NKT cells in humanized mouse models using bioluminescence imaging. [PDF]
Lyu Z, Li YR, Yang L.
europepmc +1 more source
Response to Are NKT cells a useful predictor of COVID-19 severity? [PDF]
Kreutmair S, Becher B.
europepmc +1 more source
A Case for Anti‐IgE Vaccination
ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff +3 more
wiley +1 more source
Glioma raises periodontitis risk via CD8 upregulation on NKT cells: a Mendelian randomization study. [PDF]
Jin S +5 more
europepmc +1 more source

