Results 161 to 170 of about 35,995 (263)

Editorial: NKT Cells in Cancer Immunotherapy [PDF]

Frontiers in Immunology, 2020
Tonya J. Webb, Weiming Yuan, Everett Meyer, Paolo Dellabona   +3 more
openaire   +3 more sources

Immune Evasion in Ovarian Cancer Peritoneal Metastasis: Mechanisms and Biomarker‐Guided Therapeutic Matching

Journal of Cellular Physiology, Volume 241, Issue 6, June 2026.
This graphical abstract summarizes the major immune‐evasion mechanisms that limit immunotherapy efficacy in ovarian cancer peritoneal metastasis. Peritoneal dissemination is shaped by impaired antigen visibility, coordinated immune‐evasion modules within ascites and multicellular spheroids, checkpoint‐driven T‐cell exhaustion, suppressive tumor ...
Xiaodong Wang, Junjie Wang, Di Xiong, Songli Cui, Qianqian Wang, Yiping Huang, Gouping Ding, Yixuan Tang, Yeqian Feng   +8 more
wiley   +1 more source

Targeting orthotopic and metastatic pancreatic cancer with allogeneic stem cell-engineered mesothelin-redirected CAR-NKT cells. [PDF]

Proc Natl Acad Sci U S A
Li YR, Shen X, Zhu E, Li Z, Huang J, Le T, Tran C, Radu CG, Yang L.   +8 more
europepmc   +1 more source

DAMP Laden Extracellular Vesicles From the Airways of Patients With Severe SARS‐CoV‐2 Respiratory Infection Compromise Inflammation and Cellular Metabolism

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Extracellular vesicles from severe COVID‐19 airways carry depleted miRNAs and elevated DAMPs, reprogramming monocytes toward senescence, impaired metabolism, and predominantly reduced cytokine responses. However, they drive excess IL‐8 production, amplifying neutrophil recruitment and dysfunctional inflammation across the respiratory tract.
April Rees, Oliver Richards, Molly E Raikes, Megan Chambers, Sophie G Reed, Ceri Battle, Hannah Toghill, Luke Newey, Tyler J Joseph, Haiyan An, Hui Zhang, Iain Perry, Jason Webber, Nicholas Jones, Catherine A Thornton   +14 more
wiley   +1 more source

Invariant and Diverse NKT Cells Regulate Bacterial Clearance and Pathology in Chlamydial Genital Tract Infection in Mice. [PDF]

Pathogens
Ishii K, Soejima T, Ohnishi Y, Ozuru R, Itoh R, Chou B, Yoshimura M, Shimizu A, Kurihara Y, Sakamoto A, Hiromatsu K.   +10 more
europepmc   +1 more source

Pathogenic NKT cells attenuate urogenital chlamydial clearance and enhance infertility. [PDF]

Scand J Immunol, 2023
Armitage CW, Carey AJ, Bryan ER, Kollipara A, Trim LK, Beagley KW.   +5 more
europepmc   +1 more source

Fatty Acid Metabolism in Health and Cancer: From Fundamental Mechanisms to Therapeutic Application

MedComm, Volume 7, Issue 6, June 2026.
The modulation of the TME by fatty acid metabolism primarily occurs through four key pathways: inflammation regulation, signal transduction, translation to TME, and oxidative stress. ABSTRACT Fatty acid metabolism (FAM) plays a vital role in maintaining health by supporting energy production, cellular structure, and signaling processes.
Na Hang, Runkang Zhao, Fan Zhang, Dandan Guo, Qing Li, Zhijun Shen, Ruiqing Gao, Chenyu Gao, Zhao Xie, Sentao Fu, Peng Luo, Bufu Tang, Ling Wang   +12 more
wiley   +1 more source

Protocol to generate human stem cell-derived CD70-directed allogeneic CAR-NKT cells for treating renal cell carcinoma. [PDF]

STAR Protoc
Li YR, Yang L.
europepmc   +1 more source

Effects of NKT Cells on Metabolic Disorders Caused by High-Fat Diet Using CD1d-Knockout Mice. [PDF]

Diabetes Metab Syndr Obes, 2023
Ishikawa H, Nagashima R, Kuno Y, Sasaki H, Kohda C, Iyoda M.   +5 more
europepmc   +1 more source

Single‐Cell and Spatial Transcriptomics Uncover Immune Dynamics and Cellular Heterogeneity in Benign Prostatic Hyperplasia and Prostate Cancer Transition

MedComm, Volume 7, Issue 6, June 2026.
Leveraging integrated single‐cell and spatial transcriptomics, we delineated the sustained immunosuppressive landscape during prostate disease progression. Based on this, we have developed a precise gene‐based diagnostic classifier and a multimodal prognostic model.
Yuanyuan Luo, Haitao Zhong, Tongrui Shang, Bin Hu, Dongbo Yuan, Xueyuan Jia, Ruichong Lin, Zehua Wang, Yinyi Fang, Guohua Zhu, Jukun Song, Zhangcheng Liu, Bo Yan, Fa Sun, Zhenyu Jia, Yunfang Yu, Luhui Mao, Hai Huang, Jianguo Zhu   +18 more
wiley   +1 more source