Results 141 to 150 of about 30,945 (225)

CCL20 Released by Drug–Tolerant Persisters Impairs Immunotherapy in EGFR–Mutant Lung Adenocarcinoma

MedComm, Volume 7, Issue 8, August 2026.
Schematic representation of tumor immune microenvironment (TIME) modulation by combined anti‐PD‐1 and anti‐CCL20 therapies. Left: In the “cold” tumor TIME, high CCL20 secretion by drug‐tolerant persister (DTP) cancer cell subpopulations promotes regulatory T cell (Treg) enrichment and clusters in close proximity to tumor cells, resulting in immune ...
Hoi‐Hin Kwok, Jiashuang Yang, Nerissa Chui‐Mei Lee, Junyang Deng, David Chi‐Leung Lam   +4 more
wiley   +1 more source

Protocol to generate human stem cell-derived CD70-directed allogeneic CAR-NKT cells for treating renal cell carcinoma. [PDF]

STAR Protoc
Li YR, Yang L.
europepmc   +1 more source

Effects of NKT Cells on Metabolic Disorders Caused by High-Fat Diet Using CD1d-Knockout Mice. [PDF]

Diabetes Metab Syndr Obes, 2023
Ishikawa H, Nagashima R, Kuno Y, Sasaki H, Kohda C, Iyoda M.   +5 more
europepmc   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Functional remodeling of iNKT cells by sulfatide-reactive type II NKT cells reprograms alveolar macrophages to alleviate lung ischemia-reperfusion injury. [PDF]

Commun Biol
Li Q, Yin J, Lin Q, Xu Y, He J, Shi X, Huang S, Wang Y, Huang Y, Ding X, Yu H, Nie H.   +11 more
europepmc   +1 more source

Are NKT cells a useful predictor of COVID-19 severity? [PDF]

Immunity, 2022
Koay HF, Gherardin NA, Nguyen THO, Zhang W, Habel JR, Seneviratna R, James F, Holmes NE, Smibert OC, Gordon CL, Trubiano JA, Kedzierska K, Godfrey DI.   +12 more
europepmc   +1 more source

Single Cell and Spatially Resolved Transcriptome and Immune Repertoire of Mouse Thymus During Aging Reveal Immunological Heterogeneity and Direction of Thymic Selection Pressure

Aging Cell, Volume 25, Issue 8, August 2026.
A systemic single‐cell and spatially‐resolved transcriptomics and TCR sequencing analysis across the aging thymus dissects the molecular underpinnings of T cell subset dynamics. The study highlights the shifting proportions and transcriptomic profiles of T cell subsets during aging.
Jialing Fang, Jun Lei, Peng Chen, Zaiqiao Sun, Boxiao He, Yankang Wu, Chonil Paek, Ning Wu, Yafei Huang, ZhaoKui Dan, Hui Zhang, Zijing Xu, Pengcheng Wei, Yongshun Chen, Lei Yin   +14 more
wiley   +1 more source

Oncogenic Potential of Epstein-Barr Virus in NK and NKT Cells Contribute to the Rapid Deterioration of Hemophagocytic Lymphohistiocytosis. [PDF]

J Med Virol
Cui T, Huang M, Wang Y, Lin Z, Su X, Li W, Luo Q, Li K, Wang C, Zheng R, Wang Z.   +10 more
europepmc   +1 more source

The role of NKT cells in gastrointestinal cancers. [PDF]

Oncoimmunology, 2022
Burks J, Olkhanud PB, Berzofsky JA.
europepmc   +1 more source

A cDC1‐NK/T‐Malignant Cell Circuit Drives Immunogenic Remodeling Under PD‐1 Blockade in Gastric Cancer

Cancer Science, Volume 117, Issue 8, Page 2098-2114, August 2026.
Chemotherapy combined with nivolumab reshapes the gastric cancer tumor microenvironment (TME) and is accompanied by an enrichment of reduced cytotoxicity NK (RC‐NK) cells. Rather than acting as classical cytotoxic effectors, these RC‐NK cells appear to shape the TME by promoting an immunostimulatory circuit that engages adaptive immunity.
Takuya Nakatsuru, Hiroki Yamashita, Chiaki Mashima, Guoqiang Zhang, Hitoshi Saito, Tatsunori Minamide, Keita H. Nagaoka, Ryo Kamata, Shunsuke A. Sakai, Gaku Yamamoto, Tomoko Y. Morita, Kazuki Nakai, Yumi Hakozaki, Kumi Kinoshita, Yui Takahashi, Izuma Nakayama, Akihito Kawazoe, Yuko Ishii, Sai M. Pulukuri, Hiroshi Haeno, Yukie Kashima, Kohei Shitara, Tomonori Yano, Takeshi Saito, Akihiro Ohashi   +24 more
wiley   +1 more source