The Postprandial Chronobiome in Interorgan Glucose Homeostasis
The postprandial chronobiome framework proposes that meal‐timed oscillations in microbial communities and metabolites may interact with host tissue clocks to shape glucose handling. The liver is the best‐supported temporal interpreter, while phase‐aware human studies are needed to establish causal interorgan effects.
Josko Bozic, Roko Santic, Marko Kumric
wiley +1 more source
ABSTRACT Background This study aimed to analyze the alterations in cellular and humoral immune functions, alongside cytokine profiles, in patients with recurrent aphthous ulcer (RAU) compared to those with other oral mucosal diseases and healthy controls (HC), and to investigate their clinical significance.
Yiwen Chen +3 more
wiley +1 more source
Identification of VEGFB associated with NKT cells in diabetic foot ulcers: Single-cell analysis and machine learning. [PDF]
Wang W, He Y, You T, Lei M, Chen J.
europepmc +1 more source
TCF/LEF family transcription factors: Molecular landscape and prognostic scoring in pan‐cancer
This study provides a comprehensive molecular landscape of TCF/LEF family transcription factors across 33 cancer types. We developed a TCF/LEF‐based prognostic score that correlates with immune infiltration, metabolic reprogramming and drug sensitivity, offering a robust transcriptomic signature for predicting patient survival and therapeutic response.
Zhengjun Yang +8 more
wiley +1 more source
The Dual Role of the Gut Microbiota in Cancer Chemoresistance
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi +3 more
wiley +1 more source
Targeting orthotopic and metastatic pancreatic cancer with allogeneic stem cell-engineered mesothelin-redirected CAR-NKT cells. [PDF]
Li YR +8 more
europepmc +1 more source
Turning Cold Tumors Into Hot Tumors: Implications for Cancer Therapy
Barrier‐defined strategies for cold‐to‐hot tumor conversion. Cold tumors include immune‐desert and immune‐excluded states marked by poor antigen visibility, limited T‐cell priming, stromal or vascular exclusion, metabolic stress and suppressive immune programs.
Xiao Ge +5 more
wiley +1 more source
Invariant and Diverse NKT Cells Regulate Bacterial Clearance and Pathology in Chlamydial Genital Tract Infection in Mice. [PDF]
Ishii K +10 more
europepmc +1 more source
Pathogenic NKT cells attenuate urogenital chlamydial clearance and enhance infertility. [PDF]
Armitage CW +5 more
europepmc +1 more source
Editorial: NKT Cells in Cancer Immunotherapy [PDF]
Tonya J. Webb +3 more
openaire +3 more sources

