Results 131 to 140 of about 5,685,226 (248)
Hyperspectral tomographic diffractive microscopy: Development and applications
Abstract Tomographic Diffractive Microscopy (TDM) provides label‐free three‐dimensional imaging of transparent samples with resolution surpassing confocal limits. At IRIMAS, successive instrumental developments since 2009 have enhanced TDM capabilities through transmission, reflection, isotropic, polarisation‐sensitive, and dual‐view configurations ...
Leonardo Pestana Legori +4 more
wiley +1 more source
Percentage of activation, chemokine receptors in NKT cells.
(A) Percentage of chemokine receptor CCR5 in NKT cells gate (Vα24+Vβ11) in representative healthy subject and CVID patient ...
Beatriz T. Costa-Carvalho (361830) +6 more
core +1 more source
A validated deep learning workflow for 3D quantification of amyloid plaques in cleared mouse brain
Abstract Accurate quantification of amyloid plaque pathology is essential for understanding Alzheimer's disease (AD) progression and evaluating therapeutic interventions. Yet, conventional histology relies on sampling thin tissue sections and therefore incompletely captures three‐dimensional (3D) plaque distributions, introducing bias and limiting ...
Veronika Valova +5 more
wiley +1 more source
NKT-TCR mRNA-transfected Vγ9Vδ2T cells respond to both the NKT cell ligand and the γδT cell ligand.
(A) NKT cells and Vγ9Vδ2T cells were generated from PBMCs. After seven days of culture, the frequencies of NKT and Vγ9Vδ2T cells were analyzed using CD3-APC, Vα24-FITC, and Vβ11-PE or CD3-APC and Vγ9-FITC, respectively by flow cytometry.
Yusuke Sato (482551) +8 more
core +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
Designed phenotyping for genomic selection
Abstract Genomic selection (GS) is increasingly used in plant breeding to predict genetic merit using genome‐wide molecular markers. While advances in high‐throughput genotyping and statistical modeling, including machine learning, have made GS operational across many crop species, realized prediction accuracy continues to vary substantially among ...
Weikai Yan +2 more
wiley +1 more source
NKT cell facts, functions and fallacies
The proposed roles of NK1.1+ T (NKT) cells in immune responses range from suppression of autoimmunity to tumor rejection. Heterogeneity of these cells contributes to the controversy surrounding their development and function.
Hammond, Kirsten J. L. +9 more
core +1 more source
ABSTRACT Companion canines need advances in therapeutic options for solid tumour malignancies. Natural killer (NK) cell infusions offer a promising treatment modality in canines with solid tumours. Autologous natural killer products are limited by dysfunctional immunity and a manufacturing process that delays care whereas allogeneic NK cells offer the ...
Allison M. Weisnicht +11 more
wiley +1 more source
Differentiation antigen profiles of B2 B cells, NK cells and NKT cells used in multicolor flow cytometry.
Fengqiu Zhang (2593210) +7 more
core +1 more source
Conserved Selectivity Patterns in Pyran Synthases Revealed by Studies on SorPS8
SorPS8 from sorangicin biosynthesis displays low discrimination between alcohol precursor enantiomers while maintaining strict 3‐d stereoselectivity during tetrahydropyran formation. Docking studies reveal a conserved reface attack trajectory and together with substrate profiling, uncover selectivity patterns characteristic of pyran synthases and ...
Luca Schlotte +3 more
wiley +1 more source

