Results 131 to 140 of about 35,995 (263)

Promotion of B cell responses by cognate NKT cells help.

, 2014
B cells recognize, through their B cell receptor (BCR), capsular polysaccharide Ags associated with lipids (e.g., formulated particles). BCR crosslinking leads to endocytosis and transport of Ags to endosomal compartment.
Stoyan Ivanov (340915), François Trottein (131394), Christophe Paget (340917)   +2 more
core   +1 more source

High‐Dimensional Immune Profiling Identifies Circulating NKT‐Like Cells Associated With Severity Outcome in Acute Pancreatitis at Disease Onset

Immunology, EarlyView.
High‐dimensional spectral cytometry of peripheral blood mononuclear cells at hospital admission revealed that acute pancreatitis patients who subsequently developed moderately‐to‐severe disease exhibited a specific reduction of circulating CD2 + CD8dim NKT‐like cells, which appear to acquire an altered cytotoxic‐like phenotype upon IL‐15 stimulation ...
Carolina González de Castro, Mª. Lourdes Ruiz Rebollo, Paloma Cal‐Sabater, Elisa Arribas‐Rodríguez, Álvaro Martín‐Muñoz, Alejandro Gonzalez del Hierro, Marina Perez Mazzali, Jessica Matesanz‐Isabel, Hugo Gonzalo‐Benito, Sara Cuesta‐Sancho, David Bernardo   +10 more
wiley   +1 more source

Chemotherapy pretreatment sensitizes solid tumor-derived cell lines to Vα24+ NKT cell-mediated cytotoxicity

, 2006
There is an increasing awareness of the therapeutic potential for combining immune-based therapies with chemotherapy in the treatment of malignant diseases, but few published studies evaluate possible cytotoxic synergies between chemotherapy and ...
Nieda, Mie, Tony Kenna, Andrew J. Nicol, Nicol, Andrew J., Stephen R. Mattarollo, Mie Nieda, Kenna, Tony, Mattarollo, Stephen R.   +7 more
core   +1 more source

The Transcription Factor EGR2 Plays a Central Role in the Expansion and Function of TCRαβ+CD4−CD8− Double Negative T Cells in lpr Lupus Mice

Immunology, EarlyView.
The highly expanded TCRβ+ DNT cells in autoimmune‐prone B6/lpr mice are phenotypically and functionally different from the TCRβ+DNT cells of normal B6 mice. Conditional Egr2 deletion in B6/lpr mice not only reduces TCRβ+ DNT cell numbers but also tends to correct the phenotypic and functional abnormalities of DNT cells in B6/lpr mice. In addition, Egr2
Rujuan Dai, Zhuang Wang, Bettina Heid, Christopher M. Reilly, S. Ansar Ahmed   +4 more
wiley   +1 more source

LN B-cells are increased in CTSL^nkt/nkt mice.

, 2013
LN cells from wt and CTSLnkt/nkt mice were stained with anti-B220, CD19 and IgM and analyzed by FACS. (A) Representative histograms of LN B220+ cells are shown. (B) Absolute numbers (mean ± SD; n = 4) of LN B220+CD19+cells.
Isabel Piazzon (306021), Gabriel Cabrera (358444), Hector Costa (5654527), Andrea Maglioco (216825), Roberto Pablo Meiss (401220), Maria Noel Badano (401218), Gabriela Lombardi (264876), Irene Nepomnaschy (358446), Gabriela Lorena Camicia (401219)   +8 more
core   +1 more source

Hyperspectral tomographic diffractive microscopy: Development and applications

Journal of Microscopy, EarlyView.
Abstract Tomographic Diffractive Microscopy (TDM) provides label‐free three‐dimensional imaging of transparent samples with resolution surpassing confocal limits. At IRIMAS, successive instrumental developments since 2009 have enhanced TDM capabilities through transmission, reflection, isotropic, polarisation‐sensitive, and dual‐view configurations ...
Leonardo Pestana Legori, Carlos Alberto Chacón Ávila, Matthieu Debailleul, Nicolas Verrier, Olivier Haeberlé   +4 more
wiley   +1 more source

DX5/CD49b-positive T cells are not synonymous with CD1d-dependent NKT cells

, 2005
NKT cells are typically defined as CD1d-dependent T cells that carry an invariant TCR α-chain and produce high levels of cytokines. Traditionally, these cells were defined as NK1.1 T cells, although only a few mouse strains express the NK1.1 molecule.
Hammond, Kirsten J. L., Berzins, Stuart, Brooks, Andrew G., Coquet, Jonathan, Smyth, Mark J., Kedzierska, Katherine, Turner, Stephen, Pellicci, Daniel G., Godfrey, Dale I., Kyparissoudis, Konstantinos, Keating, Rachael   +10 more
core   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

TCF/LEF family transcription factors: Molecular landscape and prognostic scoring in pan‐cancer

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
This study provides a comprehensive molecular landscape of TCF/LEF family transcription factors across 33 cancer types. We developed a TCF/LEF‐based prognostic score that correlates with immune infiltration, metabolic reprogramming and drug sensitivity, offering a robust transcriptomic signature for predicting patient survival and therapeutic response.
Zhengjun Yang, D. Q. Cai, Zhen Zhao, Zhixiang Jian, Mude Shi, Yajin Chen, Jueming Chen, Chunhua Qu, Diankui Cai   +8 more
wiley   +1 more source

NKT cells and MAIT cells in HIV/SIV infection

, 2014
© 2014 Dr. Caroline Shamala FernandezPublications included in thesis:Fernandez, C. S., Jegaskanda, S., Godfrey, D. I., & Kent, S. J. (2013). In-vivo stimulation of macaque natural killer T cells with α-galactosylceramide.
Fernandez, Caroline Shamala
core