Results 111 to 120 of about 5,685,226 (248)

A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-α and MIP1-β, a lack of IL-17, and a Th1-bias in males.

PLoS ONE, 2010
NKT cells contribute to the modulation of immune responses and are believed to be important in the pathogenesis of autoimmune and infectious diseases, as well as cancer.
Jennifer E Snyder-Cappione, Camilla Tincati, Ijeoma G Eccles-James, Amedeo J Cappione, Lishomwa C Ndhlovu, Laura L Koth, Douglas F Nixon   +6 more
doaj   +1 more source

Dynamics of NKT-cell responses to chlamydial infection

Frontiers in Immunology, 2015
Natural killer T (NKT) cells have gained great attention owing to their critical functional roles in immunity to various pathogens. In this review, we provide an overview of the current knowledge on the role of NKT cells in host defense against and ...
Sudhanshu eShekhar, Antony George Joyee, Xi eYang   +2 more
doaj   +1 more source

Tunable, High Pulse Energy and Narrow Linewidth Gas‐Filled Fiber Laser Across Near‐ and Mid‐Infrared

Laser &Photonics Reviews, EarlyView.
A cascaded gas‐filled anti‐resonant hollow‐core fiber architecture enables broadly tunable infrared Raman lasers spanning ∼1.4–4.6 µm while maintaining microjoule‐level pulse energies and gigahertz‐level linewidths. The approach combines a wavelength‐tunable pump laser with optimized Raman frequency conversion, providing a compact route to high ...
Yazhou Wang, Marcello Meneghetti, Manoj K. Dasa, Timothy Bate, J. E. Antonio‐Lopez, Ian A. Davidson, Qiang Fu, Jaroslaw Rzegocki, Gregory T. Jasion, Francesco Poletti, Rodrigo Amezcua‐Correa, Christos Markos   +11 more
wiley   +1 more source

Type II NKT cells in inflammation, autoimmunity, microbial immunity and cancer

Frontiers in Immunology, 2015
Natural killer T cells (NKT) recognize self and microbial lipid antigens presented by non-polymorphic CD1d molecules. Two major NKT cell subsets, type I and II, express different types of antigen receptors (TCR) with distinct mode of CD1d/lipid ...
Idania eMarrero, Randle eWare, Vipin eKumar   +2 more
doaj   +1 more source

Integration of scRNA‐Seq and scATAC‐Seq Revealed the Role of lncRNA RP11‐661C8.2 by Promoting EMT in Clear Cell Renal Cell Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Long noncoding RNAs (lncRNAs) play an important role in tumor progression. However, most of the previously discovered lncRNAs that promote or inhibit tumor progression were derived from bulk RNA‐seq results. Data from single‐cell RNA sequencing (scRNA‐seq) and single‐cell assay for transposase‐accessible chromatin using sequencing (scATAC‐seq)
Jizhen Cen, Xuefang Liang, Zheng Wen, Shengzhu Huang, Jiaping Li, Haibiao Yan, Kaiqiang Tang, Guifen Zhou, Ning Liang, Qi Zheng, Cheng Su, Zengnan Mo, Zhenyuan Yu   +12 more
wiley   +1 more source

Choline Deficiency Causes Colonic Type II Natural Killer T (NKT) Cell Loss and Alleviates Murine Colitis under Type I NKT Cell Deficiency. [PDF]

, 2017
Serum levels of choline and its derivatives are lower in patients with inflammatory bowel disease (IBD) than in healthy individuals. However, the effect of choline deficiency on the severity of colitis has not been investigated.
Hiroaki Niitsu, Shinji Tanaka, Ryohei Hayashi, Ryohei Hayashi (3663382), Kazuaki Chayama (128675), Yasuhiko Kitadai (3343847), Hideyuki Hyogo (480625), Kazuaki Chayama, Akira Fujita (2036128), Yoshitaka Ueno, Shintaro Sagami, Takao Hinoi, Yoshitaka Ueno (3663376), Hideyuki Hyogo, Shintaro Sagami (3663379), Akira Fujita, Shinji Tanaka (172295), Takao Hinoi (300682), Yasuhiko Kitadai, Hiroaki Niitsu (3343832), Hinoi Takao, Ueno Yoshitaka, Tanaka Shinji, Niitsu Hiroaki, Kitadai Yasuhiko, Hyogo Hideyuki, Hayashi Ryohei, Chayama Kazuaki, Fujita Akira, Sagami, Shintaro, Sagami Shintaro   +30 more
core   +2 more sources

Optically Driven AuCu Alloying in Single Nanoparticles Revealed by In Situ TEM

Small, EarlyView.
In situ transmission electron microscopy with picosecond laser illumination reveals how single gold nanorods reversibly take up and release copper from their carbon support, forming homogeneous AuCu alloys. Laser fluence and illumination time serve as control parameters, making composition dynamically tunable, and with it the functional properties it ...
Francesca Scalerandi, Loriane Monin, Nathan J. Mowry, Wiebke Albrecht   +3 more
wiley   +1 more source

The Testicular Cancer Consortium (TECAC): Filling Knowledge Gaps in the Genetic Etiology of Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The Testicular Cancer Consortium (TECAC) was established in 2012 and is comprised of researchers from over 25 centers in Europe and North America. TECAC's overarching goal is to investigate the genetic susceptibility of testicular germ cell tumors (TGCT) to better understand their biology, impact prevention strategies, and inform ...
Peter A. Kanetsky, Kristian Almstrup, Svetlana Cherlin, Victoria K. Cortessis, Alberto Ferlin, Jourik A. Gietema, Anna González‐Neira, Tom Grotmol, Robert J. Hamilton, Trine B. Haugen, Lambertus A. Kiemeney, Jung Kim, Csilla Krausz, Davor Lessel, Ragnhild A. Lothe, Kevin T. Nead, Jérémie Nsengimana, Jenny N. Poynter, Ewa Rajpert‐DeMeyts, Lorenzo Richiardi, Stephen M. Schwartz, Rolf I. Skotheim, Douglas R. Stewart, Clare Turnbull, Fredrik Wiklund, Tongzhang Zheng, Katherine L. Nathanson, Katherine A. McGlynn, for the Testicular Cancer Consortium   +28 more
wiley   +1 more source

Deficiency and dysfunctional roles of natural killer T cells in patients with ARDS

Frontiers in Immunology
ObjectiveAcute respiratory distress syndrome (ARDS) presents a global health challenge, characterized by significant morbidity and mortality. However, the role of natural killer T (NKT) cells in human ARDS remains poorly understood. Therefore, this study
Ki-Jeong Park, Tae-Ok Kim, Young-Nan Cho, Hye-Mi Jin, Young-Goun Jo, Hong-Joon Shin, Bo Gun Kho, Seung-Jung Kee, Yong-Wook Park   +8 more
doaj   +1 more source

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam, M Figura, J Heyer, S Lieber, M Huber, KL Loveland, HC Schuppe, Daniela Fietz   +7 more
wiley   +1 more source