NKT cells inhibit the development of experimental crescentic glomerulonephritis
CD1d is an MHC class I-like, beta2-microglobulin-associated protein, constitutively expressed by antigen-presenting cells and some epithelial cells, which is recognized by NKT cells, a subpopulation of T cells.
Chung, Nam Hyun +7 more
core +1 more source
This study presents a cross‐tissue, single‐cell/single‐nucleus transcriptomic atlas spanning from prenatal to postnatal developmental stages in pig, characterizing 83 distinct cell types from 252,033 cells. Through the construction of cross‐tissue transcriptional regulatory networks and pseudotime trajectories, we revealed that organogenesis is driven ...
Rong Zhou +8 more
wiley +1 more source
Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer +4 more
wiley +1 more source
Deterministic Fiber‐Optic Spectral Engineering Enables Three‐Color Multiplexed Two‐Photon Microscopy
A simulation‐guided spectral‐engineering framework maps the nonlinear parameter space of a fiber laser platform to identify balanced three‐band excitation states. The resulting 960, 1080, and 1175 nm femtosecond pulses deliver nJ‐level energies for low‐cross‐talk chromatically multiplexed two‐photon microscopy.
Marvin Edelmann +5 more
wiley +1 more source
Introduction: Natural killer T (NKT) cells are a subset of lymphocytes that express some NK cells properties. NKT cells have a regulatory role in immune responses. Little is known about the potential role of NKT cells in human infectious diseases.
A Zavaran-Hoseeni +6 more
doaj
Multispectral Concentric Grafted Perfect Vector Vortex Beam
Multispectral structured light offers powerful opportunities for increasing information capacity. A multispectral concentric grafted perfect vector vortex beam is proposed to engineer topological charges and polarization. A metasurface can graft different perfect vector vortex beams across concentric spatial regions and extend this concept to ...
Guanchao Wang +6 more
wiley +1 more source
Wavelength and Full‐Polarization Encrypted Orbital Angular Momentum Meta‐Holography
By multiplexing three independent degrees of freedom of light, a single‐layer geometric‐phase metasurface encrypts 24 distinct holographic images across 3 wavelengths, 12 pairs of orthogonal polarizations, and 4 OAM channels, taking advantage of axial chromatic dispersion to reconstruct the color images at the same plane. ABSTRACT Multiplexing multiple
Yue Han +5 more
wiley +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Role of CD44 and its v7 isoform in staphylococcal enterotoxin B-induced toxic shock : CD44 deficiency on hepatic mononuclear cells leads to reduced activation-induced apoptosis that results in increased liver damage [PDF]
Exposure to bacterial superantigens such as staphylococcal enterotoxin B (SEB) leads to the induction of toxic shock syndrome which results in multiorgan failure, including liver damage.
Fisher, M. +11 more
core +1 more source
immunoHuMiX: A personalizable gut‐on‐chip model for unraveling human microbiome–immune interactions
The study introduces a personalized gut model that brings together human immune cells and intestinal cells to better mimic how the body interacts with microbes. This system successfully maintained both human cells and a 17‐strain probiotic community, showing consistent immune responses across different donors.
Charlotte De Rudder +26 more
wiley +1 more source

