Results 121 to 130 of about 30,945 (225)

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Safety and Feasibility of Infusing Ex Vivo Expanded Allogeneic Canine Natural Killer Cells for the Treatment of Metastatic Solid Tumours

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Companion canines need advances in therapeutic options for solid tumour malignancies. Natural killer (NK) cell infusions offer a promising treatment modality in canines with solid tumours. Autologous natural killer products are limited by dysfunctional immunity and a manufacturing process that delays care whereas allogeneic NK cells offer the ...
Allison M. Weisnicht, Fernanda Szewc, Monica Moonkyung Cho, Han‐Yun Hannah Cheng, Swetha Ganesh, Lauren Mahoney, Kathryn Fox, Portia R. Smith, Mallery Olsen, Rebecca M. Richards, David M. Vail, Christian M. Capitini   +11 more
wiley   +1 more source

Novel lipid antigens for NKT cells in cancer. [PDF]

Front Immunol, 2023
Lee MS, Webb TJ.
europepmc   +1 more source

Cumulative Antigen Suppression Reduces Clonal Plasma Cell Evolution in Gaucher Disease

American Journal of Hematology, Volume 101, Issue 9, Page 2197-2213, September 2026.
ABSTRACT Chronic antigenic stimulation is implicated in the pathogenesis of monoclonal gammopathy and multiple myeloma, yet longitudinal human evidence linking sustained antigen exposure to modifiable clonal plasma cell evolution remains limited. Gaucher disease (GD), caused by biallelic GBA1 pathogenic variants, is characterized by accumulation of ...
Noor Ul Ain, Noffar Bar, Lilu Guo, Katherine Klinger, Punita Gupta, Atta Ur Rahman, Ruhua Yang, Yanhong Deng, Natalia Neparidze, Shiny Nair, Pramod K. Mistry   +10 more
wiley   +1 more source

Nootkatone inhibits the progression of glioblastoma by activating the ATF4-CHOP-CHAC1 pathway

Molecular Medicine
Glioblastoma multiforme (GBM) represents a primary brain tumor that is widely prevalent, and clinical drugs available for its treatment exhibit varying degrees of resistance. Nootkatone (NKT) is a functional sesquiterpene sourced from traditional Chinese
Qian Wang, Xiumin Xue, Zhichao Chen, Wei Zhang, Yiming Qian, Danni Chen, Lin Lin, Yinfeng Yuan, Weiqiao Zhao, Zhihui Huang, Yongjie Wang   +10 more
doaj   +1 more source

Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure

Journal of Applied Toxicology, Volume 46, Issue 9, Page 3274-3287, September 2026.
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer, Cosette Rivera‐Cruz, Alexandre M. B. Cavalca, Carlos Eduardo Fonseca‐Alves, Marxa L. Figueiredo   +4 more
wiley   +1 more source

Recent Development in Solar‐to‐Hydrogen Conversion Systems

WIREs Energy and Environment, Volume 15, Issue 3, September 2026.
This review compares three solar‐driven hydrogen production methods, photocatalysis (PC), photoelectrochemical cells (PEC), and photovoltaic–electrochemical (PV–EC) systems by examining their mechanisms, materials, stability, and efficiency. Nanocrystal‐based PC catalysts achieved the highest quantum efficiency (94%), while PV–EC and Si nanowire PEC ...
Rabia Zafar Ali, Martin D. Lennox, Milica Vasiljevic, Muhammad Imran Asghar   +3 more
wiley   +1 more source

Natural Killer T (NKT) Cells in Autoimmune Hepatitis: Current Evidence from Basic and Clinical Research. [PDF]

Cells, 2023
Poddighe D, Maulenkul T, Zhubanova G, Akhmaldtinova L, Dossybayeva K.   +4 more
europepmc   +1 more source

Imidazole‐Extended Non‐Fullerene Acceptors With Tunable Crystallinity for Ultrasensitive, Ultrafast Near‐Infrared Organic Photodetectors

Aggregate, Volume 7, Issue 8, August 2026.
A two‐dimensional extended imidazole acceptor‐based organic photodetector delivers a lower dark current of 2.54 × 10−12 A/cm−2, peak detectivity of 1.08 × 1013 Jones, the widest linear dynamic range of 167.8 dB, and ultrafast response times of 307/319 ns. ABSTRACT Emerging optoelectronic tasks such as night‐vision imaging and wearable health monitoring
Chengwei Shan, Zihao Li, Han Gao, Yuang Fu, Zhaojin Wang, Xinhui Lu, Xianyong Zhou, Bin‐Bin Yu, Philip C. Y. Chow, Aung Ko Ko Kyaw, Chang Liu, Tianshuo Zhao, Hanjian Lai   +12 more
wiley   +1 more source

A Phase I/II Study of Ibrutinib Plus Trastuzumab in HER2‐Positive Metastatic Breast Cancer

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Ibrutinib has demonstrated inhibition of ErbB/HER tyrosine kinases in preclinical models. This Phase I/II study investigated the safety, efficacy, and immunomodulatory effects of ibrutinib in combination with trastuzumab in patients with HER2‐positive metastatic breast cancer (MBC) whose disease had progressed on ado‐trastuzumab emtansine ...
Joyce O'Shaughnessy, Andrea Glidden, Tracy Locke, Amy Scales, Elizabeth Gatewood, Jean‐Philippe Blanck, Jessica Castaneda‐Gill, Sharlin Patel, Yolanda D. Mahnke, Xuan Wang, Page Blas   +10 more
wiley   +1 more source