Results 151 to 160 of about 5,685,226 (248)
Abstract A domestic shorthair cat was presented with lethargy and inappetence. Abdominal ultrasound revealed a large jejunal mural mass with diffuse wall thickening without loss of wall layering, severe jejunal lymphadenopathy, and moderate peritoneal effusion.
Riley Aronson +4 more
wiley +1 more source
Regulatory T cells (Tregs) and NKT cells are two subpopulations of T lymphocytes that independently regulate innate and adaptive immunity, but there is some evidence for cross-talk between Tregs and NKT cells, which allow a new immunoregulatory networks.
Sotošek-Tokmadžić, Vlatka +7 more
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Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller +16 more
wiley +1 more source
The Leukocyte Landscape Across Mouse Strains and Tissues
The blood, bone marrow, liver, lymph nodes, and spleen of naïve male mice contained unique immunobiomes which differed between commonly used strains. BALB‐derived strains exhibited helper‐ and innate‐biased immune profiles, C57BL/6J‐derived strains were enriched for cytotoxic and immune surveillance populations, and DBA/2 J mice displayed elevated γδ T
Ella Trolio +4 more
wiley +1 more source
In this study, we revealed the disturbed metabolic status of circulating and tumour‐infiltrating CD4+ and CD8+ T cells in melanoma patients through targeted metabolomic and lipidomic (on sorted subsets) and at single cell level using the SCENITH method.
Hugo Brouque +11 more
wiley +1 more source
ZDHHC5 may regulate the function of NKT cells and the immune response in Meniere's disease. [PDF]
Li R, Chen K.
europepmc +1 more source
Myo1g Mediates NKR‐P1C Expression in Primary Mouse NK Cells and Participates in Cytotoxicity
In this study we analysed the participation of Myosin 1g in the development and functions of murine natural killer (NK) cells; we found that Myosin 1g is expressed in murine‐activated primary NK cells from the spleen. Additionally, in the absence of Myosin 1g, correlates with a reduced expression of NKR‐P1C but not of CD49b or NKp46.
Héctor Romero‐Ramírez +3 more
wiley +1 more source
FAP-Directed CAR-NKT Cells for Multi-Target Suppression of Atherosclerotic Progression. [PDF]
Zhu E +16 more
europepmc +1 more source
Recognition of mammalian antigens by NKT cells
NKT cells are a type of lymphocyte with the ability to prevent a broad range of diseases including cancer, autoimmunity, infection and graft rejection. Sometimes, NKT cells also cause diseases, including allergy and atherosclerosis.
core
Editorial: NKT Cells in Cancer Immunotherapy [PDF]
Tonya J. Webb +3 more
openaire +3 more sources

