Results 151 to 160 of about 30,945 (225)

Multimodal targeting of metastatic renal cell carcinoma via CD70-directed allogeneic CAR-NKT cells. [PDF]

Cell Rep Med
Li YR, Hu J, Li Z, Zhu E, Chen Y, Halladay T, Shen X, Fang Y, Zhu Y, Lyu Z, Tian Y, Huang J, Zhao AS, Ma NY, Zhang C, Xie Y, Zhang H, Hsiai T, Chin AI, Wu L, Yang L.   +20 more
europepmc   +1 more source

NKT cells adopt a glutamine-addicted phenotype to regulate their homeostasis and function. [PDF]

Cell Rep, 2022
Kumar A, Yarosz EL, Andren A, Zhang L, Lyssiotis CA, Chang CH.   +5 more
europepmc   +1 more source

High‐Dimensional Immune Profiling Identifies Circulating NKT‐Like Cells Associated With Severity Outcome in Acute Pancreatitis at Disease Onset

Immunology, Volume 178, Issue 4, Page 685-703, August 2026.
High‐dimensional spectral cytometry of peripheral blood mononuclear cells at hospital admission revealed that acute pancreatitis patients who subsequently developed moderately‐to‐severe disease exhibited a specific reduction of circulating CD2 + CD8dim NKT‐like cells, which appear to acquire an altered cytotoxic‐like phenotype upon IL‐15 stimulation ...
Carolina González de Castro, Mª. Lourdes Ruiz Rebollo, Paloma Cal‐Sabater, Elisa Arribas‐Rodríguez, Álvaro Martín‐Muñoz, Alejandro Gonzalez del Hierro, Marina Perez Mazzali, Jessica Matesanz‐Isabel, Hugo Gonzalo‐Benito, Sara Cuesta‐Sancho, David Bernardo   +10 more
wiley   +1 more source

Allogeneic stem cell-engineered EGFRvIII-specific CAR-NKT cells for treating glioblastoma with enhanced efficacy and safety. [PDF]

Mol Ther
Li YR, Zhu Y, Li Z, Shen X, Halladay T, Tse C, Tian Y, Huang J, Zhao AS, Ma NY, Zhang C, Nathanson DA, Prins RM, Yang L.   +13 more
europepmc   +1 more source

Age‐Associated B Cells: Origins, Regulation, and Tissue‐Specific Pathogenic Contributions in Autoimmune, Metabolic, and Neurological Diseases

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Age‐associated B cells (ABCs) are a distinct B cell population characterized by coexpression of T‐bet and CD11c. First described in aged female mice and autoimmune‐prone strains, ABCs are now recognized to be associated with multiple human autoimmune diseases, including systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis,
Kira Rubtsova
wiley   +1 more source

Invariant NKT cells are more abundant in peanut-allergic adults and a subset of CD8⁺ iNKT cells are depleted after peanut oil exposure. [PDF]

Front Immunol, 2023
Hopkins GV, Cochrane S, Onion D, Fairclough LC.   +3 more
europepmc   +1 more source

Experimental Models of Autoimmune Hepatitis: Disease Fidelity and Translational Relevance

Liver International, Volume 46, Issue 8, August 2026.
ABSTRACT Autoimmune hepatitis (AIH) remains difficult to study mechanistically in patients because disease initiation is rarely observed directly, the relevant autoantigens differ across subsets, and clinically meaningful outcomes such as chronic inflammation, fibrosis, relapse, and treatment response evolve over time.
Laura Elisa Buitrago‐Molina, Matthias Hardtke‐Wolenski   +1 more
wiley   +1 more source

Diversity of Circulating NKT Cells in Defense against Carbapenem-Resistant Klebsiella Pneumoniae Infection. [PDF]

J Pers Med, 2022
Wang Y, Zang F, Ye X, Li Z, Zhu W, Cao X, Cai X, Ma X, Xu L, Zhang Y, Bi L, Yu R, Huang P.   +12 more
europepmc   +1 more source

Sema3E‐plexinD1 Axis Is a Modulator of Foxp3+ Regulatory T‐Cells in House Dust Mite Model of Asthma

The FASEB Journal, Volume 40, Issue 14, 31 July 2026.
Airway epithelial‐derived Sema3E enhances both the number and proliferation of Foxp3+ regulatory T (Treg) cells in an acute model of asthma. Mechanistically, deletion of PlexinD1, the receptor for Sema3E, specifically in Foxp3+ cells was associated with a breakdown in immune regulation in this model.
Mojdeh Matloubi, Chukwunonso Onyilagha, Lianyu Shan, Sujata Basu, Andrew J. Halayko, Mohamed Almiski, Abdelilah S. Gounni   +6 more
wiley   +1 more source

Targeting triple-negative breast cancer using cord-blood CD34⁺ HSPC-derived mesothelin-specific CAR-NKT cells with potent antitumor activity. [PDF]

J Hematol Oncol
Li YR, Shen X, Zhu Y, Li Z, Hon R, Tian Y, Huang J, Zhao AS, Ma NY, Zhang C, Lin D, Sargsyan K, Yuan Y, Yang L.   +13 more
europepmc   +1 more source