Results 221 to 230 of about 5,685,226 (248)

Role of NKT Cells in the Digestive System. III. Role of NKT cells in intestinal immunity

American Journal of Physiology-Gastrointestinal and Liver Physiology, 2007
Natural killer T (NKT) cells are a small subset of unconventional T cells that recognize lipid antigens presented by the nonclassical major histocompatibility complex (MHC) class I molecule CD1d. NKT cells are involved in the host response to a variety of microbial pathogens and likely commensals. In the intestine, invariant and noninvariant NKT cells
Zeissig, S, Kaser, A, Dougan, SK, Nieuwenhuis, EES, Blumberg, RS   +4 more
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T Cells and NKT Cells in the Pathogenesis of Asthma

Annual Review of Medicine, 2008
Asthma is an immunological disease with multiple inflammatory and clinical phenotypes, characterized by symptoms of wheezing, shortness of breath, and coughing due to airway hyperreactivity (AHR) and reversible airway obstruction. In allergic asthma, the most common form of asthma, airway inflammation is mediated by adaptive immune recognition of ...
Everett H, Meyer, Rosemarie H, DeKruyff, Dale T, Umetsu   +2 more
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CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy

Clinical Reviews in Allergy & Immunology
NKT cells, unique lymphocytes bridging innate and adaptive immunity, offer significant potential for managing inflammatory disorders like asthma. Activating iNKT induces increasing IFN-γ, TGF-β, IL-2, and IL-10 potentially suppressing allergic asthma.
Mohadeseh Mohammad, Taheri, Fatemeh, Javan, Mohadeseh, Poudineh, Seyyed Shamsadin, Athari   +3 more
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Roles of NKT cells in cancer immunotherapy

Archives of Pharmacal Research, 2019
Cancer immunotherapy has emerged as an effective therapeutic strategy to treat cancer. Among diverse immune populations, invariant natural killer T (iNKT) cells have shown potent antitumor activity by linking innate and adaptive immune systems. Upon activation by lipid antigens on CD1d molecules, iNKT cells rapidly produce various cytokines and trigger
Eun-Ah, Bae, Hyungseok, Seo, Il-Kyu, Kim, Insu, Jeon, Chang-Yuil, Kang   +4 more
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NKT Cell Responses to Glycolipid Activation

2009
NKT cells are a distinct lineage of T lymphocytes that are usually identified by the co-expression of the semi-invariant CD1d-restricted alphabeta TCR and the NK1.1 allelic marker of NK lineage receptors in the C57BL/6 mice and related strains. NKT cells can be subdivided based on CD4/CD8 expression and on tissue of origin.
Josianne Nitcheu, Tefit, Gwyn, Davies, Vincent, Serra   +2 more
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Liver invariant NKT cells and listeriosis

Microbes and Infection, 2008
The invariant (i) NKT cells represent unique T lymphocytes expressing TCRValpha14. Although iNKT cells have been regarded as T lymphocytes expressing NK1.1, they do not consistently express this marker. NK1.1 allows recognition of "missing-self" and thus controls inhibition/activation of iNKT cells.
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Thymic Development of Unconventional T Cells: How NKT Cells, MAIT Cells and γδ T Cells Emerge

Nature Reviews Immunology, 2020
Daniel G Pellicci, Hui-Fern Koay, Stuart P. Berzins   +2 more
exaly  

Stem Cell Epigenetics in Medical Therapy

Medical Epigenetics, 2021
Peng Jin, Liqi Shu
exaly  

The Current Landscape of NKT Cell Immunotherapy and the Hills Ahead

Cancers, 2021
Brent Johnston, Jordan D Lukács, Adam Nelson   +2 more
exaly  

The Regulatory Role of Vα14 NKT Cells in Innate and Acquired Immune Response

Annual Review of Immunology, 2003
Masaru Taniguchi, Hiroshi Wakao, Toshinori Nakayama   +2 more
exaly