Results 241 to 250 of about 35,995 (263)

Roles of NKT cells in cancer immunotherapy

Archives of Pharmacal Research, 2019
Cancer immunotherapy has emerged as an effective therapeutic strategy to treat cancer. Among diverse immune populations, invariant natural killer T (iNKT) cells have shown potent antitumor activity by linking innate and adaptive immune systems. Upon activation by lipid antigens on CD1d molecules, iNKT cells rapidly produce various cytokines and trigger
Eun-Ah, Bae, Hyungseok, Seo, Il-Kyu, Kim, Insu, Jeon, Chang-Yuil, Kang   +4 more
openaire   +2 more sources

NKT cell subsets in infection and inflammation

Immunology Letters, 2003
We recently identified two stably expressed cell surface markers, IL-18R and ST2L, which are selectively expressed on T1/NK1 and T2/NK2 cells, respectively. Here we use these molecules in direct ex vivo analysis of PBMCs from patients with AIDS, psoriasis (PS) atherosclerosis and to show the importance of these markers as determinants of the functional
Chan, WL, Pejnovic, N, Liew, TV, Lee, CA, Groves, R, Hamilton, H   +5 more
openaire   +3 more sources

NKT Cell Responses to Glycolipid Activation

2009
NKT cells are a distinct lineage of T lymphocytes that are usually identified by the co-expression of the semi-invariant CD1d-restricted alphabeta TCR and the NK1.1 allelic marker of NK lineage receptors in the C57BL/6 mice and related strains. NKT cells can be subdivided based on CD4/CD8 expression and on tissue of origin.
Josianne Nitcheu, Tefit, Gwyn, Davies, Vincent, Serra   +2 more
openaire   +2 more sources

Liver invariant NKT cells and listeriosis

Microbes and Infection, 2008
The invariant (i) NKT cells represent unique T lymphocytes expressing TCRValpha14. Although iNKT cells have been regarded as T lymphocytes expressing NK1.1, they do not consistently express this marker. NK1.1 allows recognition of "missing-self" and thus controls inhibition/activation of iNKT cells.
openaire   +2 more sources

Thymic development of unconventional T cells: how NKT cells, MAIT cells and γδ T cells emerge

Nature Reviews Immunology, 2020
Daniel G Pellicci, Hui-Fern Koay, Stuart P Berzins   +2 more
exaly  

Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells

Cell, 2018
Patricia Barral, Marianne Burbage, Malika Aid   +2 more
exaly  

Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses

Nature Immunology, 2011
Patricia Barral, Cindy S, Vincenzo Cerundolo   +2 more
exaly  

NKT cells: facts, functions and fallacies

Trends in Immunology, 2000
Dale I Godfrey, Kirsten J L Hammond, Lynn D Poulton   +2 more
exaly  

The Regulatory Role of Vα14 NKT Cells in Innate and Acquired Immune Response

Annual Review of Immunology, 2003
Masaru Taniguchi, Michishige Harada, Satoshi Kojo   +2 more
exaly  

Alternative pathway for the development of Vα14+ NKT cells directly from CD4–CD8– thymocytes that bypasses the CD4+CD8+ stage

Nature Immunology, 2017
Nyambayar Dashtsoodol, Tomokuni Shigeura, Satoshi Kojo   +2 more
exaly