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Liver invariant NKT cells and listeriosis

Microbes and Infection, 2008
The invariant (i) NKT cells represent unique T lymphocytes expressing TCRValpha14. Although iNKT cells have been regarded as T lymphocytes expressing NK1.1, they do not consistently express this marker. NK1.1 allows recognition of "missing-self" and thus controls inhibition/activation of iNKT cells.
openaire   +2 more sources

NKT Cell Responses to Glycolipid Activation

2009
NKT cells are a distinct lineage of T lymphocytes that are usually identified by the co-expression of the semi-invariant CD1d-restricted alphabeta TCR and the NK1.1 allelic marker of NK lineage receptors in the C57BL/6 mice and related strains. NKT cells can be subdivided based on CD4/CD8 expression and on tissue of origin.
Josianne Nitcheu, Tefit   +2 more
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Development and selection of NKT cells

Current Opinion in Immunology, 2002
NKT cells utilize a restricted alphabeta TCR repertoire that recognizes glycolipids in association with CD1d. The recent development of fluorescent CD1d tetramers loaded with the synthetic glycolipid alpha-galactosyl-ceramide has led to a clearer definition of NKT-cell subsets as well as important insights into their developmental origin.
openaire   +2 more sources

NKT Cell-Based Immunotherapy

2016
CD1d-restricted invariant natural killer T (NKT) cells are a specialized innate lymphocyte subset that recognizes a glycolipid antigen via the invariant T-cell receptor. Ligand-activated NKT cells display direct antitumor activities against various tumors.
openaire   +1 more source

Thymic development of unconventional T cells: how NKT cells, MAIT cells and γδ T cells emerge

Nature Reviews Immunology, 2020
Daniel G Pellicci   +2 more
exaly  

NKT cells: what's in a name?

Nature Reviews Immunology, 2004
Dale Godfrey   +2 more
exaly  

The Regulatory Role of Vα14 NKT Cells in Innate and Acquired Immune Response

Annual Review of Immunology, 2003
Masaru Taniguchi   +2 more
exaly  

Targeting natural killer cells and natural killer T cells in cancer

Nature Reviews Immunology, 2012
Eric Vivier   +2 more
exaly  

Recognition of CD1d-restricted antigens by natural killer T cells

Nature Reviews Immunology, 2012
Jamie Rossjohn   +2 more
exaly  

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