Results 131 to 140 of about 81,787 (272)

Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in pentylenetetrazole‑kindled mice. [PDF]

Int J Mol Med, 2021
Wang L, Ding J, Zhu C, Guo B, Yang W, He W, Li X, Wang Y, Li W, Wang F, Sun T.   +10 more
europepmc   +1 more source

Exposure to Gestational Intermittent Hypoxia Does Not Impair the Metabolic Function or Accelerate the Biological Ageing Process of Offspring of Either Sex

Journal of Sleep Research, EarlyView.
ABSTRACT Obstructive sleep apnea (OSA), marked by intermittent hypoxia, is associated with obesity, type 2 diabetes and metabolic associated fatty liver disease. In pregnancy, it remains underdiagnosed despite links to gestational diabetes, hypertension, and foetal growth restriction.
Esther Valverde‐Perez, Margarida B. Almeida, Joana F. Sacramento, Elena Olea, Jesus Prieto‐Lloret, Asuncion Rocher, Silvia V. Conde   +6 more
wiley   +1 more source

Imperatorin alleviated NLR family pyrin domain-containing 3 inflammasome cascade-induced synovial fibrosis and synovitis in rats with knee osteoarthritis. [PDF]

Bioengineered, 2021
Zhang H, Ding L, Shi X, Mei W, Huang Z, Zhang L, Li X, Xu B, Zhang L, Wang P.   +9 more
europepmc   +1 more source

Cell‐type‐specific gating of gene regulatory modules as a hallmark of early immune responses in Arabidopsis leaves

New Phytologist, EarlyView.
Summary In plants, multiple cell types contribute to immunity, but what division of labor exists among cell types when immunity is activated? We compared, at single‐cell resolution, the response of Arabidopsis thaliana leaf cells during pattern‐triggered and effector‐triggered immunity (PTI/ETI), sampled at 3 and 5 h after infection with Pseudomonas ...
Shanshan Wang, Ilja Bezrukov, Pin‐Jou Wu, Hannah Gauß, Marja Timmermans, Detlef Weigel   +5 more
wiley   +1 more source

Herpes Simplex Virus 1 Induces Microglia Gasdermin D-Dependent Pyroptosis Through Activating the NLR Family Pyrin Domain Containing 3 Inflammasome. [PDF]

Front Microbiol, 2022
Hu X, Zeng Q, Xiao J, Qin S, Wang Y, Shan T, Hu D, Zhu Y, Liu K, Zheng K, Wang Y, Ren Z.   +11 more
europepmc   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

Emodin relieves the inflammation and pyroptosis of lipopolysaccharide-treated 1321N1 cells by regulating methyltransferase-like 3 -mediated NLR family pyrin domain containing 3 expression. [PDF]

Bioengineered, 2022
Wang B, Liu Y, Jiang R, Liu Z, Gao H, Chen F, Mei J.   +6 more
europepmc   +1 more source

NLR family member X1 (NLRX1) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

The Evolution and Origin of Allotetraploid Aegilops geniculata Revealed by the Homoeolog‐Resolved Genome Assembly

Plant Biotechnology Journal, EarlyView.
ABSTRACT Aegilops geniculata Roth is a tetraploid (MgMgUgUg; 2n = 4x = 28) wild relative of wheat and a valuable source of genetic diversity for improving agronomic traits. We present a high‐quality homoeolog‐resolved assembly and annotation of the Ae.
Ural Yunusbaev, Gabriela Romero Campos, Rajendran Sathishraj, Evgenii Liakh, John W. Raupp, Aleksey V. Zimin, Alina Akhunova, Dal‐Hoe Koo, Eduard Akhunov   +8 more
wiley   +1 more source

Galangin Enhances Anticancer Efficacy of 5-Fluorouracil in Esophageal Cancer Cells and Xenografts Through NLR Family Pyrin Domain Containing 3 (NLRP3) Downregulation. [PDF]

Med Sci Monit, 2021
Zhang C, Luo CL, Shang GS, Jiang DX, Song Q.   +4 more
europepmc   +1 more source