Results 161 to 170 of about 81,787 (272)

The glia‐immune network: Astrocytes and oligodendrocytes as microglial co‐ordinators in health and disease

The Journal of Physiology, EarlyView.
Abstract figure legend The glia‐immune network involves the communication(s) of glia via immune signalling pathways. In neuro‐homeostasis these pathways have been shown to modulate key processes such as synaptic pruning and myelination. The dynamics of these processes is critical to CNS function.
Verity F. T. Mitchener, Millie J. Thackray, I. Lorena Arancibia‐Cárcamo   +2 more
wiley   +1 more source

Knock-down of microRNA miR-556-5p increases cisplatin-sensitivity in non-small cell lung cancer (NSCLC) via activating NLR family pyrin domain containing 3 (NLRP3)-mediated pyroptotic cell death. [PDF]

Bioengineered, 2021
Shi F, Zhang L, Liu X, Wang Y.
europepmc   +1 more source

Prognostic factors and long‐term outcomes with endoscopic submucosal dissection for colorectal tumors in patients aged 75 years or older

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Background Studies regarding the long‐term outcomes of endoscopic submucosal dissection (ESD) performed in older patients with colorectal tumors are limited. Therefore, in this study, we aimed to analyze the long‐term outcomes of older patients with colorectal tumors who underwent ESD and identify prognostic factors.
Takaya Miura, Satohiro Matsumoto, Azumi Sato, Shu Kojima, Goya Sasaki, Mina Morino, Keita Matsumoto, Hitomi Kashima, Yudai Koito, Takehiro Ishii, Shuhei Yoshikawa, Haruka Otake, Takeshi Uehara, Masanari Sekine, Takeharu Asano, Hiroyuki Miyatani, Hirosato Mashima   +16 more
wiley   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Exsomal microRNA-223 Attenuates Pyroptosis in Renal Ischemia/Reperfusion Injury by Targeting NLR Family Pyrin Domain Containing 3

, 2023
Meng Dou, Yingcong Guo, Bingxuan Zheng, Yang Li, Jin Zheng, Bo Wang, Xiaoming Ding, Wujun Xue, Puxun Tian, Huaibin Sun, Chenguang Ding   +10 more
openalex   +1 more source

Shade‐induced transcriptional reprogramming and metabolic adaptation in contrasting soybean genotypes

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Shade stress affects soybean yield in intercropping, but the molecular basis of cultivar‐specific tolerance is unclear. We analyzed shade‐tolerant (Guru) and sensitive (Heinong 53) soybeans under 30% and 70% shade using transcriptomic, physiological, and biochemical methods.
Fengyi Zhang, Runnan Zhou, Rongqiang Yuan, Xiao Zhu, Xinyue Zhang, Sobhi F. Lamlom, Dai Shi, Ahmed M. Abdelghany, Jidao Du, Honglei Ren, Lijuan Qiu   +10 more
wiley   +1 more source

Functional requirement of the Arabidopsis importin-α nuclear transport receptor family in autoimmunity mediated by the NLR protein SNC1 [PDF]

, 2020
Daniel Lüdke, Charlotte Roth, Sieglinde A. Kamrad, Jana Messerschmidt, Denise Hartken, Jonas Appel, Bojan F. Hörnich, Qiqi Yan, Stefan Kusch, Melanie Klenke, Annette Gunkel, Lennart Wirthmueller, Marcel Wiermer   +12 more
openalex   +1 more source

Integrative chromosome‐scale genome analysis of cupuassu provides insights into witches' broom disease resistance and expands genomic resources for Theobroma

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Cupuassu (Theobroma grandiflorum) is a fruit tree native to the Brazilian Amazon and increasingly relevant to regional bioeconomies. Its cultivation is severely affected by witches’ broom disease (WBD), caused by Moniliophthora perniciosa. While a chromosome‐scale genome of the susceptible genotype C1074 is available, the lack of a resistant ...
Vinicius A. C. de Abreu, Rafael Moysés Alves, Mauro de Medeiros Oliveira, Vitor Trinca, Loeni Ludke Falcão, Lucilia Helena Marcellino, Antonio Figueira, Douglas S. Domingues, Alessandro M. Varani   +8 more
wiley   +1 more source

miR-23a-5p Alleviates Gouty Inflammation by Targeting Interleukin-17A and Inhibiting NLR Family Pyrin Domain Containing 3 Inflammasome Activation. [PDF]

Arch Rheumatol
Yuan X, Lin C, Zhang Y, He H, Li L.
europepmc   +1 more source

Interleukin-18 and the NLR family pyrin domain containing-3 inflammasome in adipose tissue are strongly associated with glucometabolic variables in a cohort of middle-aged men [PDF]

, 2018
Sissel Åkra, Tonje A. Aksnes, Arnljot Flaa, Heidi B. Eggesbø, Trine B. Opstad, Ida U Njerve, Ingebjørg Seljeflot   +6 more
openalex   +1 more source