Results 211 to 220 of about 81,787 (272)
Clinical Cardiology, Volume 49, Issue 1, January 2026.ABSTRACT Background Naples Prognostic Score (NPS), a composite index incorporating inflammatory and nutritional markers, has emerged as a potential prognostic tool in various cardiovascular conditions; however, no meta‐analysis has yet pooled the available evidence to comprehensively assess its prognostic utility. Objectives To evaluate the association
Yasin Özen +8 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.Depression is common in AIH patients and is associated with an elevated cirrhosis risk. AIH patients with depression, mice colonized with MDD microbiota, and ConA‐treated mice subjected to CUMS exhibit intestinal barrier dysfunction and hepatic NLRP3 inflammasome overactivation.
Simin Zhou +15 more
wiley +1 more source
Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting
CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.Pyroptosis is a key inflammatory cell death pathway in peripheral neuropathy, with opposing roles: it perpetuates neuropathic pain but can be induced to kill neuroblastoma cells. This review consolidates mechanistic understanding and therapeutic strategies, arguing for a shift from disease‐centric to target‐centric treatment approaches to improve ...
Jinhuan Wei +11 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.Overview of study design. Metagenomic and plasma/fecal metabolomic studies were performed in 44 NSCLC patients who underwent neoadjuvant tislelizumab therapy plus platinum ‐ based doublet chemotherapy. Abstract Background Neoadjuvant anti‐programmed cell death 1 (PD‐1) immunochemotherapy has shown promising efficiency in the treatment of early‐stage ...
Ailing Cao +11 more
wiley +1 more source
Phospholipid signaling regulation is a property of the NLR family gene NLRP7.
Shahan Mamoor
openalex +1 more source
Serum Uric Acid as a Mediator of Insulin Resistance: Molecular Mechanisms and Metabolic Pathways
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.Elevated SUA can lead to oxidative stress, endothelial dysfunction, inflammation and impaired function of adipocytes—all of which collectively impede insulin receptor activity and downstream signalling. Key pathways involved include activation of the NLRP3 inflammasome, suppression of AMPK and induction of mitochondrial dysfunction.
Nurshad Ali
wiley +1 more source
Rice Blast Pathogenesis and Resistance: Effector Strategies and Host Defense Mechanisms
Food and Energy Security, Volume 15, Issue 1, January/February 2026.ABSTRACT Rice blast is the most significant disease affecting rice production, causing substantial yield loss and quality degradation. Previous studies have focused primarily on the genetic basis of pathogen resistance in rice. Recent studies have revealed the immune response mechanisms induced by pathogen‐associated molecular patterns in the pathogen ...
Lu Gan +9 more
wiley +1 more source
The Role of Viral and Bacterial Infections in the Etiology of Behçet's Disease
Journal of Clinical Laboratory Analysis, Volume 40, Issue 1, January 2026.Bacterial and viral pathogens may play a key role in Behçet's disease (BD) pathogenesis by triggering autoimmunity, molecular mimicry, or microbiome disruption. These infectious agents could initiate inflammatory pathways, contributing to BD's diverse clinical manifestations.
Mohsen Moghoofei +4 more
wiley +1 more source
Ramalin Ameliorates Alzheimer's Disease Pathology by Targeting BACE1, HDAC6, and MAPK Pathways
MedComm, Volume 7, Issue 1, January 2026.Ramalin alleviates Alzheimer's disease pathology by selectively inhibiting HDAC6, reducing BACE1 levels, and suppressing neuroinflammation through downregulation of the NLRP3 inflammasome and iNOS. It restores synaptic function impaired by Aβ toxicity and improves cognitive performance in AD mouse models, APP/PS1 and 3xTg‐AD.
Yongeun Cho +18 more
wiley +1 more source
Molecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.This study tested pectin from ripe and unripe papayas on a neonatal human stem cell‐derived intestinal model, with and without commensal Escherichia coli (E. coli). Both pectins improved cell health and reduced IL‐6, but only unripe pectin lowered IL‐8.
Janaina Lombello Santos Donadio +4 more
wiley +1 more source