Results 41 to 50 of about 81,787 (272)
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Hepatology, EarlyView., 2022 Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source
PGC-1α agonist ZLN005 ameliorates OVA-induced asthma in BALB/c mice through modulating the NF-κB–p65/NLRP3 pathway [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Asthma is a complex inflammatory disease of the lungs marked by increased infiltration of leukocytes into the airways, which restricts respiratory function.
Rui Fang +4 more
doaj +1 more source
Diabetology & Metabolic Syndrome, 2020 Background Diabetic retinopathy (DR) is a specific neurovascular complication of diabetes mellitus (DM). Clinically, family history is a widely recognized risk factor for DR, assisting diagnosis and risk strata.
Jin-Rui Wang +12 more
doaj +1 more source
Horticulturae, 2021 Nucleotide-binding leucine-rich repeat (NLR) genes play a key role in plant immune responses and have co-evolved with pathogens since the origin of green plants.
Xiao-Tong Li +5 more
doaj +1 more source
NLR regulation of the TSC family.
Both NOD2 and NLRC4 could influence or control expression of TSC22D nutrient sensor genes including control of TSC22D4 by NOD2.
Mamoor, Shahan
openalex +2 more sources
NLRC4/IPAF: a CARD carrying member of the NLR family [PDF]
Clinical Immunology, 2008 The NOD-like receptor (NLR) family of proteins is involved in the regulation of innate immune responses and cell death pathways. Recent findings show that the NLR family member NLRC4 (also known as IPAF) has important roles in innate immune responses to Gram-negative bacteria.
Fayyaz S. Sutterwala, Richard A. Flavell
openalex +3 more sources
BMC Evolutionary Biology, 2008 Background A large multigene family of NOD-like receptor (NLR) molecules have been described in mammals and implicated in immunity and apoptosis. Little information, however, exists concerning this gene family in non-mammalian taxa.
Winton James R +3 more
doaj +1 more source
Dancing with the Stars: An Asterid NLR Family
Trends in Plant Science, 2017 Wu and co-workers show how a network of sensor and helper NOD-like receptor proteins (NLRs) act together to confer robust resistance to diverse plant pathogens.
Rathjen, John, Dodds, Peter
openaire +4 more sources
Wheat Disease Resistance Genes and Their Diversification Through Integrated Domain Fusions
Frontiers in Genetics, 2020 Plants are in a constant evolutionary arms race with their pathogens. At the molecular level, the plant nucleotide-binding leucine-rich repeat receptors (NLRs) family has coevolved with rapidly evolving pathogen effectors.
Ethan J. Andersen +7 more
doaj +1 more source
Neutrophil Lymphocyte Ratio (NLR) in COVID-19 Patients Receiving Convalescent Plasma Therapy
Indonesian Journal of Medical Laboratory Science and Technology, 2022 Recently, a new RNA virus from the Coronaviridae family was discovered, known as SARS-Cov-2. This virus causes pneumonia and inflammation in the body.
Desyani Ariza +2 more
doaj +1 more source