Results 251 to 260 of about 135,752 (336)

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Turning on and off NLRP3 [PDF]

Nature Reviews Immunology, 2012
openaire   +3 more sources

Export of eDNA is a mechanism used by Mycobacterium avium subsp. hominissuis for survival within host macrophages. [PDF]

Arch Microbiol
Joseph JJ, Leestemaker-Palmer A, Bermudez LE.   +2 more
europepmc   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

JC124 confers multimodal neuroprotection in epilepsy by suppressing NLRP3 inflammasome activation: evidence from animal and human neuronal models. [PDF]

Cell Commun Signal
Zhang P, Li Z, Liang M, Yuan J, Zhou J, Zhang J, Deng J, Chen Y, Tang H, Xu C, Shi C, Ma L, Liu Q, Liu Y, Chen Y, Zhang H.   +15 more
europepmc   +1 more source

Measles Virus V Protein Inhibits NLRP3 Inflammasome-Mediated Interleukin-1β Secretion

, 2011
Noritaka Komune, Takeshi Ichinohe, Minako Ito, Yusuke Yanagi   +3 more
openalex   +1 more source

Myocardial ketone body oxidation contributes to empagliflozin‐induced improvements in cardiac contractility in murine heart failure

European Journal of Heart Failure, EarlyView.
Myocardial ketone body oxidation contributes to empagliflozin‐induced improvements in cardiac contractility. Abstract Aims Sodium–glucose cotransporter 2 inhibitors (SGLT2i) improve cardiac performance and clinical outcomes in patients with heart failure, yet mechanisms underlying these beneficial effects remain incompletely understood.
Suzanne Nathalie Voorrips, Constantin Laurent Palm, Huitzilihuitl Saucedo‐Orozco, Belend Mahmoud, Elisabeth Marloes Schouten, Anna M. Feringa, Pablo I. Sanchez‐Aguilera, Kirsten T. Nijholt, Salva R. Yurista, Peter van der Meer, Herman H.W. Silljé, B. Daan Westenbrink   +11 more
wiley   +1 more source

Progress in targeting the NLRP3 signaling pathway for inflammatory bowel disease (Review). [PDF]

Mol Med Rep
Gong Y, Han Z, Wang S, Li X, Chen X, Yang B.   +5 more
europepmc   +1 more source

Dampening insulin signaling by an NLRP3 'meta-flammasome'

, 2011
Augustine M.K. Choi, Kiichi Nakahira
openalex   +2 more sources

Activation of the NLRP3 Inflammasome by Group B Streptococci [PDF]

, 2012
Alessandro Costa, Rahul Gupta, Giacomo Signorino, Antonio Malara, Francesco Cardile, Carmelo Biondo, Angelina Midiri, Roberta Galbo, Patrick Trieu‐Cuot, Salvatore Papasergi, Giuseppe Teti, Philipp Henneke, Giuseppe Mancuso, Douglas T. Golenbock, Concetta Beninati   +14 more
openalex   +1 more source