Effects of electroacupuncture on neural function and the expression of inflammation-related proteins NLRP3/caspase-1 in rats with ischemic stroke. [PDF]
Wang Z+8 more
europepmc +1 more source
ABSTRACT TAFRO (thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly) syndrome is a rare, life‐threatening inflammatory condition linked to infections, neoplasms, and idiopathic multicentric Castleman disease. Interleukin (IL)‐6 inhibitors are the primary treatment, but refractory cases require alternatives. This
Serena Palmeri+10 more
wiley +1 more source
Inflammasomes: novel therapeutic targets for metabolic syndrome? [PDF]
Cao P, Yang Y, Zhang N, Wang B, Gong Z.
europepmc +1 more source
The Role of Magnesium in Liver Cirrhosis
Magnesium is a vital mineral involved in over 300 enzymatic reactions, crucial for physiological functions. Its deficiency, common in liver cirrhosis patients, correlates with poor outcomes by affecting inflammation, oxidative stress, fibrosis, and immunity. This review explores magnesium's role in cirrhosis and its interaction with disease mechanisms.
Weiye Zeng+4 more
wiley +1 more source
NLRP3 inflammasome expression affects immune cell infiltration and clinical prognosis in <i>Helicobacter pylori</i> infection‑associated gastric cancer. [PDF]
Wan C, Xu Y, Zhu Y, Cao X, Wang P, Gu Y.
europepmc +1 more source
Interleukin‐1 receptor type II and inflammatory bowel disease: A Mendelian randomization study
This Mendelian Randomization study investigated the association between interleukin‐1 receptor type II (IL‐1RII) and inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC) by utilizing the genome‐wide association studies summary statistics.
Qifan Feng+7 more
wiley +1 more source
Pentraxin 3 promotes the expression of pro-inflammatory cytokines and the migration of macrophages in myocarditis. [PDF]
Zhu T+9 more
europepmc +1 more source
Both native and engineered extracellular vesicles (EVs) are served as promising therapeutic agents for treating acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). To circumvent the limitations of native EVs, various engineering strategies are adopted.
Zhengyan Gu+12 more
wiley +1 more source
Computational drug discovery of phytochemical alkaloids targeting the NACHT/PYD domain in the NLRP3 inflammasome. [PDF]
Singh N+7 more
europepmc +1 more source