Results 261 to 270 of about 131,202 (338)

Efficacy of High‐Dose Intravenous Anakinra in Pediatric TAFRO Syndrome: Report of Two Cases and Literature Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT TAFRO (thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly) syndrome is a rare, life‐threatening inflammatory condition linked to infections, neoplasms, and idiopathic multicentric Castleman disease. Interleukin (IL)‐6 inhibitors are the primary treatment, but refractory cases require alternatives. This
Serena Palmeri   +10 more
wiley   +1 more source

Inflammasomes: novel therapeutic targets for metabolic syndrome? [PDF]

open access: yesFront Endocrinol (Lausanne)
Cao P, Yang Y, Zhang N, Wang B, Gong Z.
europepmc   +1 more source

The Role of Magnesium in Liver Cirrhosis

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Magnesium is a vital mineral involved in over 300 enzymatic reactions, crucial for physiological functions. Its deficiency, common in liver cirrhosis patients, correlates with poor outcomes by affecting inflammation, oxidative stress, fibrosis, and immunity. This review explores magnesium's role in cirrhosis and its interaction with disease mechanisms.
Weiye Zeng   +4 more
wiley   +1 more source

Interleukin‐1 receptor type II and inflammatory bowel disease: A Mendelian randomization study

open access: yesRheumatology &Autoimmunity, EarlyView.
This Mendelian Randomization study investigated the association between interleukin‐1 receptor type II (IL‐1RII) and inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC) by utilizing the genome‐wide association studies summary statistics.
Qifan Feng   +7 more
wiley   +1 more source

Pentraxin 3 promotes the expression of pro-inflammatory cytokines and the migration of macrophages in myocarditis. [PDF]

open access: yesBMC Cardiovasc Disord
Zhu T   +9 more
europepmc   +1 more source

Native and Engineered Extracellular Vesicles for the Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome

open access: yesSmall Science, EarlyView.
Both native and engineered extracellular vesicles (EVs) are served as promising therapeutic agents for treating acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). To circumvent the limitations of native EVs, various engineering strategies are adopted.
Zhengyan Gu   +12 more
wiley   +1 more source

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