Results 281 to 290 of about 133,275 (336)

IGFBP5 promotes EndoMT and renal fibrosis through H3K18 lactylation in diabetic nephropathy. [PDF]

Cell Mol Life Sci
Hu X, Chen W, Yang M, Li M, Li X, Ouyang S.   +5 more
europepmc   +1 more source

Quercetin and Allopurinol Ameliorate Kidney Injury in STZ-Treated Rats with Regulation of Renal NLRP3 Inflammasome Activation and Lipid Accumulation

, 2012
Chuang Wang, Ying Pan, Qingyu Zhang, Fu‐Meng Wang, Ling‐Dong Kong   +4 more
openalex   +2 more sources

Mitochondrial transfer as a novel therapeutic approach in ischemic stroke treatment: Current challenges and future perspectives

Neuroprotection, EarlyView.
Cerebral ischemia is a serious neurological disease that mainly leads to pathological changes such as mitochondrial dysfunction, oxidative stress and iron death. Mitochondria play a key role in the regulation of cellular energy metabolism and oxidative stress, and their damage can lead to mitochondrial damage, reduced adenosine triphosphate production,
Shuchen Meng, Min Bai, Changsheng Ma, Bo Han, Mengyuan Duan, Liying Zhang, Jinfen Guo, Changku Shi, Ke Li, Maotao He   +9 more
wiley   +1 more source

PRDM16 acts as a homeostasis regulation factor to suppress the transition of AKI to CKD via upregulation of eukaryotic initiation factor 6. [PDF]

Cell Mol Life Sci
Li X, Xia Y, Li X, Guo Y, Qiu S, Li H, Li Y, Wu L, Zhang D.   +8 more
europepmc   +1 more source

Role of astrocyte in neuroinflammation‐induced loss in neuroplasticity and subsequent onset of depression: A systematic review

Neuroprotection, EarlyView.
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal, Saurabh Singhal, Bernhard T. Baune   +2 more
wiley   +1 more source

The NLRP3 inflammasome is essential for IL-18 production in a murine model of macrophage activation syndrome

Disease Models & Mechanisms
Tara A. Gleeson, Christina Kaiser, Catherine B. Lawrence, David Brough, Stuart M. Allan, Jack P. Green   +5 more
doaj   +1 more source

Pterostilbene Reduces Cyclophosphamide-Induced Interstitial Cystitis by Facilitating Nrf2 Activation and Suppressing the NLRP3 Inflammasome Pathway. [PDF]

Int J Mol Sci
Zhang J, Wang J, Wang X, Yan Z, Meng L, Zhang Y.   +5 more
europepmc   +1 more source

Constitutively Activated NLRP3 Inflammasome Causes Inflammation and Abnormal Skeletal Development in Mice

, 2012
Sheri L. Bonar, Susannah Brydges, James L. Mueller, Matthew D. McGeough, Carla A. Peña, Debbie Chen, Susan K. Grimston, Cynthia L. Hickman‐Brecks, Soumya Ravindran, Audrey McAlinden, Deborah V. Novack, Daniel L. Kastner, Roberto Civitelli, Hal M. Hoffman, Gabriel Mbalaviele   +14 more
openalex   +2 more sources

Altered Bacteria Abundance Is Associated With Outcomes in Head and Neck Squamous Cell Carcinoma

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To determine if microbiome differences exist in head and neck squamous cell carcinoma (HNSCC) based on high‐risk pathologic features, smoking, and outcomes using The Cancer Microbiome Atlas (TCMA). Study Design Database study. Setting Database review.
Delaney H. Sheehan, Kesava Asam, Nicolaus D. Knight, Juhi J. Patel, James A. Stewart, Patrick A. Molina, Nengjun Yi, Chi T. Viet, Brad Aouizerat, Natalie Silver, Bharat Panuganti, Carissa M. Thomas   +11 more
wiley   +1 more source

Role of MS4A7 in Regulating Microglial Polarization and Neuroinflammation in Spinal Cord Injury via the cGAS-STING-NLRP3 Axis. [PDF]

CNS Neurosci Ther
Li X, Liu J, Deng Y, Xing F, Lu X, Zhang Z, Li C.   +6 more
europepmc   +1 more source