Results 161 to 170 of about 28,373 (282)

Targeting <i>EZH2</i> oncogenic splicing: decoding the regulatory network and antisense correction. [PDF]

Genes Dev
Islam MR, Nagar P, McNaughton N, Heeamoni SA, Hasan MM, Kandel S, Mukta IJ, Tsakiroglou P, Dalton WB, Abdel-Wahab O, Krainer AR, Rahman MA.   +11 more
europepmc   +1 more source

Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6- and SMG7-mediated degradation pathways

, 2016
Besides degrading aberrant mRNAs that harbor a premature translation termination codon (PTC), nonsense-mediated mRNA decay (NMD) also targets many seemingly “normal” mRNAs that encode for full-length proteins.
Mühlemann, Oliver
core  

Microbiome Insights Into Zoonotic Risk at Wildlife–Human Interfaces in a Transitioning Landscape in Thailand

Integrative Zoology, EarlyView.
This study shows how ecological transitions, such as reforestation in Southeast Asia, reshape host–microbe–pathogen dynamics at the wildlife–domestic interface. By integrating long‐read microbiome sequencing, ecological gradients, and statistical and network analysis, we identify host species that disproportionately contribute to pathogen diversity and
Pauline Van Leeuwen, Chuanpot Thinphovong, Vincent Sluydts, Alix Nicolas, Anamika Kritiyakan, Areeya Kriengudom, Pipat Soisook, Kittipong Chaisiri, Serge Morand, Johan Michaux   +9 more
wiley   +1 more source

Low-frequency repetitive transcranial magnetic stimulation attenuates visceral pain in IBS with diarrhoea via inhibition of the medial prefrontal cortex. [PDF]

Gut
Weng RX, Lin W, Sun Q, Ma CT, Ma CT, Zhang FC, Jia SM, Hu S, Li YC, Zhang CH, Yu YJ, Zhao WM, Xu GY, Li R.   +13 more
europepmc   +1 more source

Fragment Edges Benefit a Common Predator of Pollinators via Bottom‐Up Effects

Integrative Zoology, EarlyView.
This study investigated the hypotheses regarding the effects of habitat fragmentation on spider biomass and causing bottom‐up or top‐down effects on multi‐trophic relationships. ABSTRACT Defaunation following habitat fragmentation typically threatens predators at higher trophic levels, which further alter prey and plants via top‐down effects.
Wenlong Zhou, Peng Ren, Marcel Holyoak, Donghao Wu, Chen Zhu, Wenjie Zhou, Ping Ding, Mingjian Yu   +7 more
wiley   +1 more source

Clinical outcomes of paediatric home ventilation in South Korea: liberation and mortality. [PDF]

BMJ Open Respir Res
Moon JW, Jang JE, Lee MJ, Lee MY, Kim K, Park JD, Lee JW, Kim MS, Park JS, Suh DI.   +9 more
europepmc   +1 more source

Gut Microbiota Analysis and Comparison in Forest Musk Deer (Moschus berezovskii) of Different Ages and Musk‐Secreting Periods

Integrative Zoology, EarlyView.
Metagenomic sequencing was used to analyze fecal microbiota of captive male forest musk deer (FMD) from the Sichuan Institute of Musk Deer Breeding across ages and musk‐secreting periods. Gut microbiota was generally stable and dominated by Firmicutes, while age and musk secretion shaped microbial composition and function, with musk collection linked ...
Jiuyan Jiang, Qiuping Huang, Fei Wu, Pingwei Liang, Linping Fan, Xia Zhou, Chengli Zheng, Xin Shi, Huina Song, Ji Wang, Jing Xue Luo, Ji Chen, Qinlin Yang, Siqi Peng, Lingqian Yin, Dejun Zeng, Hang Jie, Guangxiang Zhu   +17 more
wiley   +1 more source

Long-read transcriptome analysis using IsoRanker for identifying pathogenic variants in Mendelian conditions. [PDF]

Am J Hum Genet
Cheng YH, Sedeño-Cortés AE, Ranchalis JE, Munson KM, Vollger MR, Balton E, Genetti CA, Undiagnosed Diseases Network, Genomics Research to Elucidate the Genetics of Rare Diseases consortium, University of Washington Center for Rare Diseases Research, Wilson JL, Wojcik MH, Beggs AH, Bamshad MJ, Wei CL, Dipple KM, Kumar RD, Fleming MD, Glass IA, Blue EE, Jarvik G, Chong JX, Witten DM, O'Donnell-Luria A, Stergachis AB.   +24 more
europepmc   +1 more source

Is Cone‐Beam CT Reliable for Apical Foramen Assessment? A Micro‐CT–Referenced Study

Australian Endodontic Journal, EarlyView.
ABSTRACT This study evaluated the diagnostic accuracy of two cone‐beam CT (CBCT) dose protocols for identifying the number and trajectory deviation of apical foramina. Forty lower molars were scanned in Micro‐CT. Thereafter, all teeth were inserted into the mandible sockets and a titanium implant and an endodontically treated tooth with a cobalt ...
João Pedro de Lima, Guilherme Nilson Alves dos Santos, Manoel Damião Sousa‐Neto, Amanda Pelegrin Candemil   +3 more
wiley   +1 more source

Nonsense-Mediated Decay mRNA Quality Control System Is Essential for Root Development and Efficient Root Nodule Symbiosis in Medicago truncatula. [PDF]

Plant Cell Environ
Biró JB, Péter C, Domonkos Á, Hegedűs Z, Lakatos L, Rana D, Gyula P, Silhavy D, Kaló P.   +8 more
europepmc   +1 more source