Results 151 to 160 of about 28,373 (282)

The lung microbiome in childhood-onset severe neuromuscular disease with respiratory insufficiency: rationale, current evidence, and opportunities for oxford nanopore long-read sequencing. [PDF]

Mol Cell Pediatr
Cirak S, Grieshaber V, Müller P, Chao CM.   +3 more
europepmc   +1 more source

Production of human cell lines with mutations and deletions in endogenous NMD factors using CRISPR/Cas genome editing

, 2016
Nonsense-mediated mRNA decay (NMD) is a eukaryotic RNA degradation pathway that modulates the abundance of 3-10% of all cellular mRNAs in mammalian cells.
Nasif, Sofia, Mühlemann, Oliver
core  

Responses of Soil Arthropod Communities to Varying Shading Levels in Agriphotovoltaic Systems

Integrative Zoology, EarlyView.
Soil fauna was primarily influenced by crop type and season rather than AgriPhotovoltaic (APV) panels. Elevated panels increased soil temperature and soil organic matter in early wheat stages, while shading enhanced soil moisture for tomatoes, benefiting moisture‐sensitive taxa.
Cristina Menta, Aldo Dal Prà, Jasmine Scartozzi, Federico Gavinelli, Giuseppe Concheri, Piergiorgio Stevanato, Gabriele Testa, Giancarlo Ghidesi, Sara Remelli   +8 more
wiley   +1 more source

PRMT1-SFPQ regulates intron retention to control matrix gene expression during craniofacial development. [PDF]

Elife
Lima JR, Ungvijanpunya N, Chen Q, Pham HQH, Rosen T, Park G, Vantankhah M, Yen S, Chai Y, Merrill AE, Liu Z, Chen JF, Yang Y, Peng W, Xu J.   +14 more
europepmc   +1 more source

Position-Dependent NMD Generates Diverse Protein Outcomes

Nonsense-mediated mRNA decay (NMD) is a translation-dependent mRNA decay pathway triggered by premature termination codons (PTCs). Although NMD is known to eliminate aberrant transcripts, how PTC position influences cell-to-cell heterogeneity in NMD and ...
Nusrat Jahan Pinky, Hanae Sato
core   +1 more source

Decades of Enclosure Protection Exert Composite Effects on Grassland Grasshopper Communities

Integrative Zoology, EarlyView.
Decades of enclosure protection have altered grasshopper community structure, with species‐specific effects on population dynamics. For the low‐mobility grasshopper Chorthippus fallax, abundance did not differ strongly between exclosure‐protected and overgrazed areas, but its egg development duration was longer in exclosures. The two C.
Dan‐dan Feng, Hui‐feng Zhao, Ya‐hui Men, Jing Li, Mei‐ling Yang, Cai‐qing Yang, Bing Chen, Ai‐bing Zhang   +7 more
wiley   +1 more source

Artificial Intelligence in Neuromuscular Diseases: Opportunities for a Data-Scarce Field. [PDF]

Neurol Ther
Ma S, Luo S, Zhong H.
europepmc   +1 more source

Association Characteristics and Potential Mechanisms of Aging, Gut Microbiota, and Hearing Loss

Integrative Zoology, EarlyView.
The study found that aging leads to unchanged gut microbiota alpha diversity but an increase in Bacteroidetes and a decrease in Firmicutes at the phylum level, with specific genera, species, and functional pathways co‐associated with aging and hearing loss. Through constructing a microbe‐metabolite network, it revealed the mechanism by which protective
Cheng Cheng, Lu Wang, Runhan Li, Wenkai Lai, Chongkui Sun, Jianguo Cui, Bicheng Zhu, Jiang Zhang   +7 more
wiley   +1 more source

Signatures of nonsense-mediated mRNA decay but no evidence for transcriptional adaptation associated with protein-truncating variants in wild yeast diploids. [PDF]

Mol Biol Evol
Marszałek M, Babik W, Korona R, Tomala K.   +3 more
europepmc   +1 more source

Seasonal Dynamics of Community and Function of Gut Microbiome in Taihangshan Macaque (Macaca mulatta tcheliensis): Inferred From Metagenomic Data

Integrative Zoology, EarlyView.
A total of 435 non‐redundant metagenome‐assembled genomes (MAGs) were obtained from fecal samples of Taihangshan macaque across all four seasons. The alpha diversity of the gut microbiome in spring and winter was significantly higher than in summer and autumn. Furthermore, marked differences were detected in functional pathways and carbohydrate enzymes
Yanyan Zhou, Qi Shao, Chunbo Liu, Jundong Tian, Xiaowen Guan, Xi Zhang, Jiqi Lu   +6 more
wiley   +1 more source