IBD is driven by a vicious cycle of dysbiosis, barrier dysfunction, and immune dysregulation. We developed an inulin–butyrate conjugate nanogel (IBN) that accumulates in inflamed colon and releases butyrate via microbial inulinase/esterase. The inulin shell remodels the microbiome, while localized butyrate strengthens barrier integrity and promotes ...
Nayoon Park +7 more
wiley +1 more source
Cytogenotoxic Effects of Fluopyram in Allium cepa Root Cells Involving Microtubule Disruption
ABSTRACT Fluopyram is a next‐generation fungicide widely used in agriculture; however, its persistence in soils and mobility toward aquatic systems have raised concerns regarding potential ecotoxicological risks. This study evaluated the cytogenotoxic effects of a commercial fluopyram‐based pesticide formulation on Allium cepa root meristem cells ...
Carlos Filipe Camilo‐Cotrim +10 more
wiley +1 more source
immunoHuMiX: A personalizable gut‐on‐chip model for unraveling human microbiome–immune interactions
The study introduces a personalized gut model that brings together human immune cells and intestinal cells to better mimic how the body interacts with microbes. This system successfully maintained both human cells and a 17‐strain probiotic community, showing consistent immune responses across different donors.
Charlotte De Rudder +26 more
wiley +1 more source
Regional nonsense constraint offers biological and clinical insights into genetic disease. [PDF]
Blakes AJM +4 more
europepmc +1 more source
Tree cover and geographic origin of tree species drive bird functional groups in urban environments
Urban trees provide habitat and resources for wild species in cities and support biodiversity provision of ecosystem services, among which insect control is particularly relevant. Predators of insects are promoted by the presence of trees and, in turn, may enhance biosecurity of the trees.
Marco Basile +2 more
wiley +1 more source
Alternative splicing-triggered mRNA decay informs splice-switching targets for neurodevelopmental disorders. [PDF]
Hu K +7 more
europepmc +1 more source
DNA metabarcoding reveals wolf dietary patterns in the northern Alps and Jura Mountains
Understanding predator–prey interactions is crucial for wildlife management and human–wildlife coexistence, particularly in multi‐use landscapes such as western Europe. As wolves Canis lupus recolonize their former habitats, knowledge of their diet is essential for conservation, management and public acceptance.
Florin Kunz +6 more
wiley +1 more source
Urban bats show dietary flexibility in aquatic arthropod consumption at urban and rural waterbodies
Urban waterbodies are critical for biodiversity and provide feeding grounds for insectivorous bats. Yet, how urbanisation affects bats' food choices at urban waterbodies and the role of emergent aquatic arthropods remain poorly understood. We compared the diet of three urban bat species – Vespadelus vulturnus, Chalinolobus gouldii,and Myotis macropus –
Tanja M. Straka +7 more
wiley +1 more source
Urban greenspaces are a haven for wildlife in densely populated cities. Wildlife use greenspaces for resource acquisition, shelter, and travel across urbanized landscapes. Greenspace metrics such as herbaceous or woody landcover, size, patchiness, and human land use influence species richness.
Adrianna J. Elihu, Janel L. Ortiz
wiley +1 more source
Composite SMG5-SMG6 PIN domain formation is essential for NMD. [PDF]
Kurscheidt K +6 more
europepmc +1 more source

