Results 161 to 170 of about 240,251 (364)
Reduction of NMDA receptors with dithiothreitol increases [3H]‐MK‐801 binding and NMDA‐induced Ca2+ fluxes [PDF]
, 1990 Ian J. Reynolds +2 more
openalex +1 more source
Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management
Medicinal Research Reviews, EarlyView.ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh +4 more
wiley +1 more source
Neuroprotection, EarlyView.Abstract Postoperative delirium (POD), a prevalent neurological complication in older surgical patients, adversely affects recovery. Isoflurane, a common inhalational anesthetic, exhibits neurotoxic potential, but its role in POD pathogenesis remains unclear.
Zhiming Dai +3 more
wiley +1 more source
Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery
PROTEOMICS, EarlyView.ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam +12 more
wiley +1 more source
Suppressing effects of various nootropic drugs on voltage-sensitive Ca2+ channels and NMDA channels
, 1989 Shuji Kaneko +5 more
openalex +1 more source
Multi‐Channel Neural Interface for Neural Recording and Neuromodulation
Small Methods, EarlyView.This review highlights recent advances in multi‐channel neural interface technologies, covering both high‐resolution electrophysiological recording systems and multifunctional platforms with integrated capabilities. It also discusses innovations in structure and materials for reduced invasiveness, state‐of‐the‐art data analysis, including machine ...
Eunmin Kim +9 more
wiley +1 more source
Veterinary Record Case Reports, EarlyView.Abstract Providing perioperative analgesia in farm animal species is often hampered by limited analgesic agent availability, legal restrictions, or an absence of licensed products. A 38.7 kg, 6‐month‐old male Boer goat presented for surgical repair of a non‐strangulated umbilical hernia.
Nadiah Syuhada Roslan +3 more
wiley +1 more source
The contributions of NMDA, non-NMDA, and GABA receptors to postsynaptic responses in neurons of the optic tectum [PDF]
, 1993 PW Hickmott, Martha Constantine‐Paton
openalex +1 more source
Mechanism of Ammonia‐Induced Brain Damage in Chinese Striped‐Necked Turtle (Mauremys sinensis)
Integrative Zoology, EarlyView.High levels of ammonia disrupt the integrity of the brain barrier in Mauremys sinensis, leading to tissue edema. This, in turn, triggers a series of cascade reactions, including disturbances in neurotransmitter levels, particularly glutamate, which might further exacerbate the neurotoxic effects.
Yunjuan Xiao +6 more
wiley +1 more source