Results 171 to 180 of about 110,732 (265)
Abstract Objective High‐grade astrocytomas, including glioblastomas, are aggressive brain tumors with poor prognosis and a 5‐year survival below 7%. Seizures affect up to 75% of glioma patients, especially in low‐grade tumors but also in high‐grade cases.
Matteo Impellizzeri +7 more
wiley +1 more source
FDA Approval of Donanemab-azbt: A New Dawn in Alzheimer's Disease Treatment. [PDF]
Riaz R +8 more
europepmc +1 more source
Using [18F]‐SMBT‐1 PET, we longitudinally tracked MAO‐B–expressing reactive astrocytes during orofacial neuropathic pain development in rats, revealing region‐ and time‐specific astrocyte activation during pain chronification. ABSTRACT Chronic neuropathic pain represents a significant global health burden and is hypothesized to be maintained by an ...
Lewis S. Crawford +14 more
wiley +1 more source
DXM, CYP2D6-inhibiting antidepressants, piracetam, and glutamine: proposing a ketamine-class antidepressant regimen with existing drugs. [PDF]
Cheung N.
europepmc +1 more source
Epigenetic and Brain Structure Covariation Patterns in Typical and Atypical Development
We present a map linking DNA methylation to brain structure in childhood. Genes in which methylation was linked to brain anatomy are highly enriched for those implicated in psychiatric and neurodevelopmental disorders, highlighting potential epigenetic targets for understanding both typical and atypical brain development.
Valentine Chirokoff +5 more
wiley +1 more source
Clinical characteristics and outcomes of anti-NMDA receptor-dominant autoimmune encephalitis. [PDF]
Guo M, Xu D.
europepmc +1 more source
ABSTRACT The cognitive abilities of many non‐human animals have been investigated in recent years; however, outside of laboratory rodent strains, it is largely unknown how direct and indirect genetic factors influence the development of cognition. In a previous study, we found no impact of maternal genetic or non‐genetic effects on problem solving in ...
Misha K. Rowell, Tasmin L. Rymer
wiley +1 more source
Prevalence of anti-NMDA receptor antibodies among adult patients presenting with first-episode psychosis in Hong Kong. [PDF]
Chau SWH +4 more
europepmc +1 more source
Astrocytes in Genetic Epilepsies: Supporting Actor or Key Player?
Astrocytes contribute to the pathophysiology of acquired epilepsy. However, less is known about their contribution to genetic epilepsy syndromes which often exhibit frequent comorbidity with neurodevelopmental and psychiatric disorders. Epileptic seizures are also frequently present in neurodevelopmental disorders.
Jenny Lange +4 more
wiley +1 more source

