Results 171 to 180 of about 110,343 (264)

Clonidine Inhibits Interictal-like Epileptiform Events in Prefrontal Cortex Pyramidal Neurons. [PDF]

Int J Mol Sci
Kołba W, Herbst D, Szulczyk B.
europepmc   +1 more source

Evaluating Anesthetics for Improving Scientific Research and Welfare Using Larval Zebrafish

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Using physiological and behavioral assays, we quantified the effectiveness and appropriateness of six commonly used fish anesthetics on zebrafish embryos. Different anesthetics performed better under different contexts. Figure prepared using BioRender.com.
Sylvia Dimitriadou, Mhairi Miller, Ali Pilehvar, Lynne U. Sneddon, Jessica L. Bamsey, Damilola Hogan‐Bassey, Maciej Trznadel, Jonathan S. Ball, Aya Takesono, Courtney Hillman, Hannah Rickard, Grace Popplewell, Jenna Corcoran, Tetsuhiro Kudoh, Charles R. Tyler, Matthew J. Winter   +15 more
wiley   +1 more source

Modulation of NMDA Receptor and TRPM4 Activity in Hippocampal Neurons with the NMDA Receptor/TRPM4 Interface Inhibitor Brophenexin. [PDF]

Neurotox Res
Casby J, Allen RK, Marron Fernandez de Velasco E, Thayer SA.   +3 more
europepmc   +1 more source

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

eFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie, Wei Fang, Zean Song, Zhang Yu, Ying Zhu, Shaoping Liu   +5 more
wiley   +1 more source

Non-Invasive Temporal Interference Electrical Stimulation Modulates Neurotransmitter Release and Improves Aberrant Neural Oscillations in Alzheimer's Disease. [PDF]

CNS Neurosci Ther
Wu L, Li S, Huang L, Li L, Zhou P, Lu Z, Liu T, Wang J.   +7 more
europepmc   +1 more source

An iEEG investigation on sex‐specific differences in seizure duration

Epilepsia Open, Volume 11, Issue 3, Page 912-921, June 2026.
Abstract Objective Male people with epilepsy (mPWE) are at higher risk for bilateral tonic–clonic seizures (BTCs) and sudden unexpected death in epilepsy (SUDEP) compared to female people with epilepsy (fPWE). Despite major clinical and personal implications, little is known about sex‐specific differences in seizure propagation and termination ...
Paula Albert I Gracenea, Alexandra Muss, Magdalena Seethaler, Jan Rémi, Elisabeth Kaufmann   +4 more
wiley   +1 more source

Magnesium Transporter SLC41A1 Links Magnesium Homeostasis to NMDA Receptor-Related Synaptic Dysfunction: A Transdiagnostic Therapeutic Target for Neuropsychiatric Disorders. [PDF]

Biomedicines
Chen X, Deng W, Chen X, Yu Y.
europepmc   +1 more source

Energy metabolism, adenosine, and glutamate signaling reprogramming by decanoic acid in Glut1 disorder syndrome

Epilepsia Open, Volume 11, Issue 3, Page 1036-1045, June 2026.
Abstract Glut1 deficiency syndrome (Glut1DS) leads to neurological and cognitive symptoms and is primarily treated using carbohydrate‐restricted ketogenic diets. However, a recent clinical trial of a less restrictive, non‐ketogenic, medium chain triglyceride (MCT) diet with a high decanoic acid content suggests efficacy in Glut1DS treatment.
Erwann Pain, Yatra Kapatel, Pankaj K. Singh, Katie Lloyd Jones, Jamuna Selvakumaran, Alberto Malerba, Walter Lucchesi, Tricia Rutherford, Christina A. Gurnett, Matthew C. Walker, Robin S. B. Williams   +10 more
wiley   +1 more source

Müller glia derived EVs promote neurite recovery of an enriched population of retinal ganglion like cells derived from hESC retinal organoids after damage. [PDF]

Sci Rep
Eastlake K, Lamb WDB, Tracey-White D, Shibagaki K, Khaw PT, Jayaram H, Limb GA.   +6 more
europepmc   +1 more source

Locus‐Specific Genetic Associations at the DAOA Gene in Schizophrenia and Bipolar Disorder

Advanced Genetics, Volume 7, Issue 2, June 2026.
This study explores locus‐specific genetic associations at the DAOA gene in schizophrenia (SZ) and bipolar disorder (BD). Using genotype, haplotype, and phenotype analyses, the authors identify a variant (rs2391191) showing associations with both disorders, while another variant (rs1935062) shows no disease association but exploratory links to clinical
Madiha Khalid, Muhammad Mukhtar, Muhammad Saqlain, Abdul Sami, Shahid Mehmood Baig, Amber Nawaz, Sadaf Moeez, Ch Muhammad Fahim Ayaz, Tahzeeb Fatima, Farah Fatima, Janghoo Lim, Muhammad Nawaz, Ghazala Kaukab Raja   +12 more
wiley   +1 more source