Results 171 to 180 of about 110,732 (265)

Perampanel as add‐on in high‐grade glioma–related epilepsy: Seizure control and QoL in a prospective, multicenter, real‐world 6‐month follow‐up study

open access: yesEpilepsia Open, Volume 11, Issue 4, Page 1137-1148, August 2026.
Abstract Objective High‐grade astrocytomas, including glioblastomas, are aggressive brain tumors with poor prognosis and a 5‐year survival below 7%. Seizures affect up to 75% of glioma patients, especially in low‐grade tumors but also in high‐grade cases.
Matteo Impellizzeri   +7 more
wiley   +1 more source

FDA Approval of Donanemab-azbt: A New Dawn in Alzheimer's Disease Treatment. [PDF]

open access: yesHealth Sci Rep
Riaz R   +8 more
europepmc   +1 more source

Longitudinal Tracking of Astrocyte Reactivity During the Development of Chronic Orofacial Neuropathic Pain Using [18F]‐SMBT‐1 Positron‐Emission Tomography

open access: yesGlia, Volume 74, Issue 8, August 2026.
Using [18F]‐SMBT‐1 PET, we longitudinally tracked MAO‐B–expressing reactive astrocytes during orofacial neuropathic pain development in rats, revealing region‐ and time‐specific astrocyte activation during pain chronification. ABSTRACT Chronic neuropathic pain represents a significant global health burden and is hypothesized to be maintained by an ...
Lewis S. Crawford   +14 more
wiley   +1 more source

Epigenetic and Brain Structure Covariation Patterns in Typical and Atypical Development

open access: yesHuman Brain Mapping, Volume 47, Issue 11, 01 August 2026.
We present a map linking DNA methylation to brain structure in childhood. Genes in which methylation was linked to brain anatomy are highly enriched for those implicated in psychiatric and neurodevelopmental disorders, highlighting potential epigenetic targets for understanding both typical and atypical brain development.
Valentine Chirokoff   +5 more
wiley   +1 more source

Is the Cognitive Ability of Fawn‐Footed Mosaic‐Tailed Rat Melomys cervinipes Offspring Related to Mothers’ Care or Cognitive Abilities?

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 7, Page 785-794, August 2026.
ABSTRACT The cognitive abilities of many non‐human animals have been investigated in recent years; however, outside of laboratory rodent strains, it is largely unknown how direct and indirect genetic factors influence the development of cognition. In a previous study, we found no impact of maternal genetic or non‐genetic effects on problem solving in ...
Misha K. Rowell, Tasmin L. Rymer
wiley   +1 more source

Astrocytes in Genetic Epilepsies: Supporting Actor or Key Player?

open access: yesJournal of Neuroscience Research, Volume 104, Issue 8, August 2026.
Astrocytes contribute to the pathophysiology of acquired epilepsy. However, less is known about their contribution to genetic epilepsy syndromes which often exhibit frequent comorbidity with neurodevelopmental and psychiatric disorders. Epileptic seizures are also frequently present in neurodevelopmental disorders.
Jenny Lange   +4 more
wiley   +1 more source

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