Results 171 to 180 of about 217,671 (368)

Ictal index finger pointing and politician's fist as localizing clinical signs in a pediatric patient

Epileptic Disorders, EarlyView.
Joshua Chang, Mohamed Taha, Douglas Nordli III   +2 more
wiley   +1 more source

The effectiveness of oral and sublingual ketamine in pain management: a systematic review and meta‐analysis

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Aim The aim of this study was to undertake a systematic review and meta‐analysis to determine the effectiveness of oral and sublingual ketamine in pain management. Data Sources A systematic search was conducted utilising four databases: MEDLINE, CINAHL, Embase, and Web of Science. Study Selection The study included randomised controlled trials
Stephanie Elizabeth Harris, Jeremy Szmerling, Diarna Abbott, Enwu Liu, John Oldroyd   +4 more
wiley   +1 more source

Pulsed Electromagnetic Fields: A Novel Attractive Therapeutic Opportunity for Neuroprotection After Acute Cerebral Ischemia

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Acute cerebral ischemia is characterized by several pathological processes evolving during time, which contribute to the final tissue damage. Secondary processes, such as prolonged inflammatory response, impaired mitochondrial function and oxidative stress, are responsible for the progression of brain injury to the peri‐infarct area,
Fioravante Capone, Simona Salati, Fabrizio Vincenzi, Micaela Liberti, Giorgio Aicardi, Francesca Apollonio, Katia Varani, Ruggero Cadossi, Vincenzo Di Lazzaro   +8 more
wiley   +1 more source

Serotonin Modulates Oscillations of the Membrane Potential in Isolated Spinal Neurons from Lampreys [PDF]

, 2002
Studies were performed on spinal neurons from lampreys isolated by an enzymatic/mechanical method using pronase. The effects of 100 µM serotonin (5-HT) on membrane potential oscillations induced by a variety of excitatory amino acids were studied.
Batueva, I. V., Buchanan, James, Suderevskaya, E. I., Tsvetkov, E. A., Veselkin, N. P.   +4 more
core   +1 more source

The Effects of Serotonin on Functionally Diverse Isolated Lamprey Spinal Cord Neurons [PDF]

, 2002
The experiments reported here showed that application of serotonin (5-hydroxytryptamine, 5-HT) (100 µ M) did not induce any significant current through the membranes of any of the spinal neurons studied (n = 62).
Batueva, I. V., Buchanan, James T., Suderevskaya, E. I., Tsvetkov, E. A., Veselkin, N. P.   +4 more
core   +1 more source

Pairing the cholinergic agonist carbachol with patterned Schaffer collateral stimulation initiates protein synthesis in hippocampal CA1 pyramidal cell dendrites via a muscarinic, NMDA-dependent mechanism [PDF]

, 1993
Sherry L. Feig, Peter Lipton
openalex   +1 more source

Generalization of NMDA-Receptor Antagonists to the Discriminative Stimulus Effects of κ-Opioid Receptor Agonists U-50,488H, but Not TRK-820 in Rats

Journal of Pharmacological Sciences, 2006
.: Generalizations of NMDA-receptor antagonists to the discriminative stimulus effects of κ-opioid receptor agonists in rats were examined. Phencyclidine, MK-801, and ketamine, noncompetitive NMDA-receptor antagonists, generalized to the discriminative ...
Tomohisa Mori, Mutsuko Nomura, Kazumi Yoshizawa, Hiroshi Nagase, Toshiko Sawaguchi, Minoru Narita, Tsutomu Suzuki   +6 more
doaj  

NLX‐112 Randomized Phase 2A Trial: Safety, Tolerability, Anti‐Dyskinetic, and Anti‐Parkinsonian Efficacy

Movement Disorders, EarlyView.
Abstract Background Levodopa‐induced dyskinesia (LID) in Parkinson's disease (PD) is associated with ‘false neurotransmitter’ release of dopamine from serotonin (5‐HT) neurons. NLX‐112 is a first‐in‐class, highly selective 5‐HT1A receptor agonist which counteracts LIDs in experimental PD models.
Per Svenningsson, Per Odin, Filip Bergquist, Karin Wirdefeldt, Dag Nyholm, Mattias Andréasson, Ioanna Markaki, Anders C. Johansson, Måns Jergil, Christopher Jankosky, Mark A. Varney, Fabienne Herbrecht, Steven A. Johnson, Adrian Newman‐Tancredi   +13 more
wiley   +1 more source

Towards an understanding of the pathological basis of senile depression and incident dementia: Implications for treatment

Psychiatry and Clinical Neurosciences, Volume 76, Issue 12, Page 620-632, December 2022., 2022
Senile depression (SD) is a heterogeneous syndrome. Several clinical profiles are more likely to appear in SD than in early‐life depression, but it remains unclear whether the pathophysiology is different. The prevalence of dementia increases with aging, and the underlying pathophysiological processes in the preclinical phase begin even before ...
Ito Kawakami, Jun‐ichi Iga, Sho Takahashi, Yi‐Ting Lin, Hiroshige Fujishiro   +4 more
wiley   +1 more source

Kindling induces the long-lasting expression of a novel population of NMDA receptors in hippocampal region CA3 [PDF]

, 1994
J.E. Kraus, GC Yeh, DW Bonhaus, J. Victor Nadler, JO McNamara   +4 more
openalex   +1 more source