Results 181 to 190 of about 217,671 (368)

The Neuroprotective Effect of Cannabinoid Receptor Agonist (WIN55,212-2) in Paraoxon Induced Neurotoxicity in PC12 Cells and N-methyl-D-aspartate Receptor Interaction [PDF]

open access: yesCell Journal, 2010
Objective: Considering that cannabinoids protect neurons against neurodegeneration, inthis study, the neuroprotective effect of WIN55,212-2 in paraoxon induced neurotoxicity inPC12 cells and the role of the N-methyl-D-aspartate (NMDA) receptor were ...
Hedayat Sahraei   +4 more
doaj  

An overview of the non‐procedural treatment options for peripheral neuropathic pain

open access: yesMuscle &Nerve, EarlyView.
Abstract Peripheral neuropathic pain is common in patients with peripheral nerve injury and can significantly impact both their function and quality of life. There is a wide variety of non‐interventional treatment approaches, including pharmacologic therapy, physical/occupational therapy, modalities (therapeutic, mechanical, thermal, etc.), psychology,
Evan R. Zeldin   +6 more
wiley   +1 more source

A caregiver's perspective on clinically relevant symptoms in behavioural variant frontotemporal dementia: tools for disease management and trial design

open access: yesPsychogeriatrics, Volume 23, Issue 1, Page 11-22, January 2023., 2023
ABSTRACT Background Adequate detection of symptoms and disease progression in behavioural variant frontotemporal dementia (bvFTD) is complex. Dementia cohorts usually utilize cognitive and functional measures, which fail to detect dominant behavioural and social cognitive deficits in bvFTD.
Jay L.P. Fieldhouse   +9 more
wiley   +1 more source

Crosstalk Between Brain-Derived Neurotrophic Factor And N-Methyl-D-Aspartate Receptor Signaling In Neurons [PDF]

open access: yes, 2008
Glutamate is the major excitatory neurotransmitter in brain exerting prosurvival effect on neurons via N-methyl-D-aspartate receptor (NMDAR) signaling under physiological conditions.
Georgiev, Danko   +3 more
core  

Prevalence of potentially inappropriately prescribed medications among older adults receiving peritoneal dialysis

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
Abstract Introduction The prevalence of exposure to supratherapeutic doses or contraindicated medications based on renal dosing criteria, also known as potentially inappropriately prescribed medications (PIPM), is currently unknown among patients on peritoneal dialysis (PD).
Armando Silva Almodovar   +3 more
wiley   +1 more source

The effect of schizophrenia risk factors on mismatch responses in a rat model

open access: yesPsychophysiology, Volume 60, Issue 2, February 2023., 2023
Abstract Reduced mismatch negativity (MMN), a robust finding in schizophrenia, has prompted interest in MMN as a preclinical biomarker of schizophrenia. The rat brain can generate human‐like mismatch responses (MMRs) which therefore enables the exploration of the neurobiology of reduced MMRs.
Jaishree Jalewa   +4 more
wiley   +1 more source

Assessment of degree of risk from sources of microbial contamination in cleanrooms; 1: Airborne [PDF]

open access: yes, 2015
The degree of risk from microbial contamination of manufactured products by sources of contamination in healthcare cleanrooms has been assessed in a series of three articles.
Eaton, T., Whyte, W.
core  

Oral morphine used to control intensive pain in a dog (canis familiaris) with tonsil carcinoma, and metastasis in medial retropharyngeal lymph node

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract An 11‐year‐old, female West Highland white terrier presenting cough, emesis, diarrhoea and hyporexia refractory to symptomatic treatment was subjected to endoscopy showing increased palatine tonsil region. Biopsy findings revealed a carcinoma. Computed tomography also showed an increased right medial retropharyngeal lymph node dorsally related
Jiuli R. S. de Salles   +2 more
wiley   +1 more source

Reaching the Goal: Superior Navigators in Late Adulthood Provide a Novel Perspective into Successful Cognitive Aging

open access: yesTopics in Cognitive Science, Volume 15, Issue 1, Page 15-45, January 2023., 2023
Abstract Normal aging is typically associated with declines in navigation and spatial memory abilities. However, increased interindividual variability in performance across various navigation/spatial memory tasks is also evident with advancing age. In this review paper, we shed the spotlight on those older individuals who exhibit exceptional, sometimes
Ruojing Zhou   +2 more
wiley   +1 more source

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