Results 51 to 60 of about 240,251 (364)
Journal of Pain Research, 2023 Ristiawan Muji Laksono,1,2 Handono Kalim,3 Mohammad Saifur Rohman,4 Nashi Widodo,5 Muhammad Ramli Ahmad,6 Willy Halim7 1Doctoral Program in Biomedical Science, Faculty of Medicine, Brawijaya University, Malang, Indonesia; 2Department of Anesthesiology ...
Laksono RM +5 more
doaj
The Dichotomy of NMDA Receptor Signaling [PDF]
The Neuroscientist, 2007 The N-methyl-D-aspartate (NMDA) subtype of ionotropic glutamate receptors plays a Jekyll and Hyde role in the mammalian central nervous system. In pathological scenarios such as ischemia, Ca2+ influx through the NMDA receptor is a key mediator of cell death.
Papadia, Sofia, Hardingham, Giles
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Advanced Materials, EarlyView.Hydrogen‐bond‐driven interface engineering enables highly linear and symmetric artificial synapses based on CsPbI3–PVA hybrids. This strategy suppresses trap states and guides directional ion migration, yielding stable optoelectronic plasticity. The devices achieve ultralow power operation and human‐like learning in neuromorphic networks, offering a ...
Min Jong Lee +10 more
wiley +1 more source
Localization of NMDA receptors in the cerebral cortex: a schematic overview
Brazilian Journal of Medical and Biological Research, 1997 The fundamental role of N-methyl-D-aspartate (NMDA) receptors in many cortical functions has been firmly defined, as has its involvement in a number of neurological and psychiatric diseases.
F. Conti
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Frontiers in Molecular Neuroscience, 2022 For decades, N-methyl-D-aspartate (NMDA) receptors have been known to play a critical role in the modulation of both acute and chronic pain. Of particular interest are NMDA receptors expressed in the superficial dorsal horn (SDH) of the spinal cord ...
Annemarie Dedek +3 more
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Pathologically Activated Neuroprotection via Uncompetitive Blockade of \u3cem\u3eN\u3c/em\u3e-Methyl-d-aspartate Receptors with Fast Off-rate by Novel Multifunctional Dimer Bis(propyl)-cognitin [PDF]
, 2010 Uncompetitive N-methyl-d-aspartate (NMDA) receptor antagonists with fast off-rate (UFO) may represent promising drug candidates for various neurodegenerative disorders.
Fu, Hongjun +13 more
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Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology. [PDF]
, 2009 The cause(s) of sporadic Alzheimer's disease (sAD) are complex and currently poorly understood. They likely result from a combination of genetic, environmental, proteomic and lipidomic factors that crucially occur only in the aged brain.
Green, Kim N
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Toward Advancement of Fabrication Techniques of Neuromorphic Computing Devices Based on 2D Materials
Advanced Materials Technologies, EarlyView.This review highlights emerging fabrication techniques of 2D material‐based neuromorphic devices, emphasizing proximity vapor transfer for bioinspired optoelectronic applications. Abstract The growing necessity for power‐efficient and cognitive computation mechanisms has driven progress in neuromorphic computing which seeks to imitate the synaptic ...
Shubham Umeshkumar Gupta +7 more
wiley +1 more source
BMC Neuroscience, 2008 Background Extrasynaptic NMDA receptors couple to a CREB shut-off pathway and cause cell death, whereas synaptic NMDA receptors and nuclear calcium signaling promote CREB-mediated transcription and neuronal survival.
Bading Hilmar +2 more
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Remembering Mechanosensitivity of NMDA Receptors [PDF]
Frontiers in Cellular Neuroscience, 2019 An increase in post-synaptic Ca2+ conductance through activation of the ionotropic N-methyl-D-aspartate receptor (NMDAR) and concomitant structural changes are essential for the initiation of long-term potentiation (LTP) and memory formation. Memories can be initiated by coincident events, as occurs in classical conditioning, where the NMDAR can act as
Luke R. Johnson +9 more
openaire +5 more sources