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The Clinical Significance of Abnormal Electroencephalography (EEG) Patterns in Patients with Neuropsychiatric Disorders Due to Anti-NMDA Receptor Encephalitis: A Comparative Study [PDF]
DiagnosticsBackground: Anti-NMDA receptor encephalitis is an autoimmune disease characterized by severe neuropsychiatric disturbances, often misdiagnosed as a primary psychiatric disorder.
Alvaro Moreno-Avellán +11 more
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NMDA receptor blockade attenuates Japanese encephalitis virus infection-induced microglia activation [PDF]
Journal of NeuroinflammationNeurodegeneration and neuroinflammation are key components in the pathogenesis of Japanese Encephalitis caused by Japanese Encephalitis Virus (JEV) infection.
Cheng-Yi Chang +8 more
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Treatment of Cerebral Ischemia Through NMDA Receptors: Metabotropic Signaling and Future Directions
Frontiers in Pharmacology, 2022 Excessive activation of N-methyl-d-aspartic acid (NMDA) receptors after cerebral ischemia is a key cause of ischemic injury. For a long time, it was generally accepted that calcium influx is a necessary condition for ischemic injury mediated by NMDA ...
Yuanyuan Li +20 more
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NMDA Receptors in Astrocytes [PDF]
Neurochemical Research, 2019 Astrocytes support glutamatergic neurotransmission in the central nervous system through multiple mechanisms which include: (i) glutamate clearance and control over glutamate spillover due to operation of glutamate transporters; (ii) supply of obligatory glutamate precursor glutamine via operation of glutamate-glutamine shuttle; (iii) supply of L ...
Alexandr Chvátal +3 more
openaire +6 more sources
Biomolecules, 2022 Various ASD risk alleles have been associated with impairment of NMDA receptor activation (i.e., NMDA Receptor Hypofunction) and/or disturbance of the careful balance between activation mediated by GluN2B-subtype and GluN2A-subtype-containing NMDA ...
Stephen I. Deutsch +2 more
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Bortezomib in the management of anti-NMDA receptor encephalitis
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2023 Background Anti-N-methyl d-aspartate (NMDA) receptor encephalitis is an autoimmune encephalitis characterized by neuronal surface antibodies targeting NMDA receptor in the spinal fluid and serum.
Bryan Gervais de Liyis +6 more
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Memory and the NMDA Receptors [PDF]
New England Journal of Medicine, 2009 Ablating mice of Neto1, a component that stabilizes a postsynaptic glutamate receptor, results in a deficit in memory and learning — a deficit ameliorated by administration of a glutamate-receptor stimulant.
Joe Z. Tsien, Fei Li
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COVID−19, Anti-NMDA Receptor Encephalitis and MicroRNA
Frontiers in Immunology, 2022 The coronavirus disease 2019 (COVID-19) pandemic has had an enormous impact on the world, affecting people’s lifestyle, economy, and livelihood. Recently, with the development of vaccines, the number of infected cases has decreased.
Hsiuying Wang
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Blockade of the N-Methyl-D-Aspartate Glutamate Receptor Ameliorates Lipopolysaccharide-Induced Renal Insufficiency. [PDF]
PLoS ONE, 2015 N-methyl-D-aspartate (NMDA) receptor activation in rat kidney reduces renal perfusion and ultrafiltration. Hypoperfusion-induced ischemia is the most frequent cause of functional insufficiency in the endotoxemic kidney.
Chian-Shiung Lin +3 more
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Alzheimer’s Research & Therapy, 2021 Background The cannabinoid CB2 receptor (CB2R), which is a target to afford neuroprotection, and N-methyl-D-aspartate (NMDA) ionotropic glutamate receptors, which are key in mediating excitatory neurotransmission, are expressed in both neurons and glia ...
Rafael Rivas-Santisteban +7 more
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