Results 121 to 130 of about 43,559 (247)

NMDAR antibody ΔMFI at different serum dilutions in NMDAR antibody positive and negative sera.

, 2015
NMDAR antibody positive (n = 9) and negative (n = 12) serum samples have been determined by CBA. (A) Serum dilutions of 1:100 and 1:20 are shown. Respective cut-off ΔMFI values are indicated by dashed horizontal lines.
Regina Irschick (713453), Florian Deisenhammer (89557), Patrick Peschl (713452), Markus Reindl (89559), Thomas Berger (72614), Romana Höftberger (363160), Kevin Rostásy (713454), Josep Dalmau (394113), Melanie Ramberger (713451), Kathrin Schanda (365014)   +9 more
core   +1 more source

Reduction in hippocampal cholinergic neurostimulating peptide enhances memory impairment in AppNL‐G‐F KI mice

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Whether cholinergic activity in the septohippocampal network affects cognitive dysfunction via hippocampal cholinergic neurostimulating peptide (HCNP) in Alzheimer's pathogenesis remains unclear. METHODS An Alzheimer's pathogenesis by mutation in amyloid‐beta precursor protein gene (AppNL‐G‐F) knock‐in (KI) and HCNP precursor ...
Yo Tsuda, Yuta Madokoro, Kengo Suzuki, Takuya Ooba, Toyohiro Sato, Yuto Uchida, Itsumi Nagai‐Arakawa, Takashi Saito, Hideaki Hara, Hideki Hida, Noriyuki Matsukawa   +10 more
wiley   +1 more source

Serum and CSF anti-NMDAR antibody testing in psychiatry

, 2019
The authors examined and compared the clinical presentation of CSF positive and negative -methyl-d-aspartate receptor (NMDAR) antibody.The investigators performed a retrospective chart review of NMDAR-antibody-positive cases (serum or CSF) involving ...
Warren, Nicola, Prain, Kerri, Gillis, David, O'Gorman, Cullen, Siskind, Dan, Swayne, Andrew, Blum, Stefan   +6 more
core   +1 more source

Contributions of the Alzheimer's Disease Neuroimaging Initiative to advancing AD research: a targeted review of recent publications

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) recently celebrated its 20th anniversary, reflecting two decades of major contributions to Alzheimer's research through open data sharing and longitudinal multimodal assessments. This review synthesizes 122 high‐impact studies using ADNI data or biospecimens from 2023 to mid‐2025 to ...
Dallas P. Veitch, Melanie J. Miller, Shaveta Kanoria, Paul S. Aisen, Laurel A. Beckett, Robert C. Green, Danielle J. Harvey, Clifford R. Jack Jr., William Jagust, Edward B. Lee, Kwangsik Nho, Rachel Nosheny, Ozioma C. Okonkwo, Richard J. Perrin, Ronald C. Petersen, Monica Rivera Mindt, Andrew J. Saykin, Leslie M. Shaw, Arthur W. Toga, Duygu Tosun, Susan M Landau, Michael W. Weiner, for the Alzheimer's Disease Neuroimaging Initiative   +22 more
wiley   +1 more source

Respective roles of eCB and NMDAR signaling pathways.

, 2018
eCB- (left) and NMDAR- (right) dependent plasticity only computed numerically as a function of the number of pairings and Δt, together with experimental points obtained from [39, 40] by pharmalogically impairing, respectively, NMDAR- or eCB-dependent ...
Jonathan D. Touboul (5628521), Gaëtan Vignoud (5628518), Laurent Venance (169698)   +2 more
core   +1 more source

Mitochondrial NADK2‐dependent NADPH controls tau oligomer uptake in human neurons

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Reduced brain energy metabolism, mitochondria dysfunction, and extracellular tau oligomer buildup characterize Alzheimer's disease (AD), but how these phenomena cooperatively promote neurodegeneration is poorly understood. We now report that tau oligomers (TauOs) pathologically coordinate mitochondrial metabolism with increased ...
Evelyn Pardo, Taylor Kim, Horst Wallrabe, Kristine E. Zengeler, Vijay Kumar Sagar, Garnett Mingledorff, Xuehan Sun, Ammasi Periasamy, John R. Lukens, George S. Bloom, Andrés Norambuena   +10 more
wiley   +1 more source

Role of the NMDAR-NR2B Subunit in the Function of Supramolecular NMDAR-BK Complexes [PDF]

Biophysical Journal, 2021
Rebeca Martínez Lázaro, David Bartolome-Martin, Ricardo Gomez, Teresa Giraldez   +3 more
openaire   +1 more source

CSF‐Compartmentalized Antibody Glycoprofiles in NMDAR Encephalitis Associate with Etiology and Functional Recovery

Annals of Neurology, Volume 99, Issue 6, Page 1468-1479, June 2026.
Objective To characterize Fc‐glycosylation profiles in patients with anti‐N‐methyl‐D‐aspartate receptor encephalitis (NMDARe) and assess their association with antibody compartmentalization (cerebrospinal fluid [CSF] vs serum), disease triggers (viral, tumor‐related or idiopathic), and 1‐year outcomes.
Laura Marmolejo, Claudia Papi, Chiara Milano, Esther Aguilar, Estibaliz Maudes, Ivana Duvnjak Orešković, Jerko Štambuk, Maja Pučić‐Baković, Gemma Olivé‐Cirera, Elianet Fonseca, Mar Guasp, Eugenia Martinez‐Hernandez, Helena Ariño, Takahiro Iizuka, Thais Armangué, Josep Dalmau, Marianna Spatola   +16 more
wiley   +1 more source

NMDAR Down-Regulation: Dual – Hit Molecular Target For COPD – Depression Comorbidity

Uriel Heresco-Levy,1,2 Jacob Haviv,1 Yehezkel G Caine1 1Herzog Medical Center, Jerusalem, Israel; 2Psychiatry Department, Hadassah Medical School, Hebrew University, Jerusalem, IsraelCorrespondence: Uriel Heresco-Levy, Herzog Medical Center, POBox 3900 ...
Heresco-Levy U, Haviv J, Caine YG
core  

Flux-Independent NMDAR Signaling: Molecular Mediators, Cellular Functions, and Complexities

, 2018
The glutamate (Glu) N-methyl-d-aspartate (NMDA) receptor (NMDAR) plays a critical role in synaptic communication given mainly by its ionotropic function that permeates Ca2+.
Pavel Montes de Oca Balderas
core   +1 more source