Results 101 to 110 of about 23,536 (264)

Identification of a 3-aminoimidazo[1,2-a]pyridine inhibitor of HIV-1 reverse transcriptase

open access: yesVirology Journal, 2012
Background Despite the effectiveness of highly active antiretroviral therapy (HAART), there remains an urgent need to develop new human immunodeficiency virus type 1 (HIV-1) inhibitors with better pharmacokinetic properties that are well tolerated, and ...
Elleder Daniel   +6 more
doaj   +1 more source

Resurgence of Sexually Transmitted Hepatitis C Virus Infection in Men Who Have Sex With Men Living With HIV

open access: yesJournal of Medical Virology, Volume 98, Issue 10, October 2026.
ABSTRACT In 2023–2025, HCV transmission in men who have sex with men (MSM) living with HIV in Hong Kong resurged. This study aims to assess the epidemiologic patterns between 2011 and 2025. Among 288 MSM with sexually acquired HCV infection, 73% were diagnosed at least 12 months after HIV diagnosis, and 98% had ever achieved HIV viral load suppression.
Shui‐Shan Lee   +4 more
wiley   +1 more source

Prevalence of major NRTI and NNRTI resistance mutations in individuals with transmitted drug resistance.

open access: yes, 2016
Absolute and cumulative prevalence of each major nucleoside (NRTI) and nonnucleoside RT Inhibitor (NNRTI) drug-resistance mutation (DRM) in individuals with intermediate or high-level transmitted NRTI or NNRTI resistance from a meta-analysis of 287 ...
Neil Parkin (273844)   +31 more
core   +1 more source

The Influence of Plasma and Peritoneal Antiretroviral Drugs Levels on the Shedding of HIV‐1 Into Peritoneal Dialysis Effluent

open access: yesJournal of Medical Virology, Volume 98, Issue 10, October 2026.
ABSTRACT Penetrance of antiretroviral therapy in the peritoneal cavity and its influence on the shedding of HIV‐1 into continuous ambulatory peritoneal dialysis (CAPD) was investigated. This prospective cross‐sectional study of HIV‐positive end‐stage kidney failure (ESKF) patients managed with ART and CAPD, collected enrolled patients' demographic ...
Teboho Mooko   +8 more
wiley   +1 more source

Kaplan-Meier estimates of risk for NNRTI-related skin rash according to CD4 count at baseline.

open access: yes, 2014
Kaplan-Meier estimates of risk for NNRTI-related skin rash according to CD4 count at baseline.
Fred Stephen Sarfo (139071)   +4 more
core   +1 more source

Relationship between Minority NNRTI Resistance Mutations, Adherence, and the Risk of Virologic Failure

open access: yesAIDS (London), 2012
Objectives:To evaluate the risk of virologic failure conferred by suboptimal adherence to nonnucleoside reverse transcriptase inhibitors (NNRTIs) and minority NNRTI resistance mutations.
Jonathan Z. Li   +8 more
semanticscholar   +1 more source

Highly Efficient Synthesis of HIV NNRTI Doravirine

open access: yes, 2016
The development of an efficient and robust process for the production of HIV NNRTI doravirine is described. The synthesis features a continuous aldol reaction as part of a de novo synthesis of the key pyridone fragment. Conditions for the continuous flow
David M. Tschaen (1633039)   +7 more
core   +1 more source

Treatment outcomes and plasma level of ritonavir-boosted lopinavir monotherapy among HIV-infected patients who had NRTI and NNRTI failure [PDF]

open access: yes, 2009
Background Different strategies of ritonavir-boosted lopinavir monotherapy have been explored; however, data regarding salvage therapy among HIV-infected patients who failed nucleoside reverse transcriptase inhibitor (NRTI) and non-nucleoside reverse ...
Thongyen Supeda   +15 more
core   +1 more source

Nevirapine induced toxic epidermal necrolysis and non-Hodgkin lymphoma in a Human Immunodeficiency Virus positive patient

open access: yesIndian Dermatology Online Journal, 2014
Nevirapine, a non-nucleoside reverse transcriptase inhibitor (NNRTI) is one of the important components of highly active antiretroviral therapy. It is sometimes associated with life-threatening adverse reactions.
Leelavathy Budamakuntla   +4 more
doaj   +1 more source

An Intravaginal Ring That Releases the NNRTI MIV-150 Reduces SHIV Transmission in Macaques

open access: yesScience Translational Medicine, 2012
An intravaginal ring loaded with the NNRTI MIV-150 prevents transmission of the HIV/SIV chimera SHIV-RT in macaques. HIV Protection That Has a Ring to It An ounce of prevention is better than a pound of cure.
R. Singer   +16 more
semanticscholar   +1 more source

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