Results 111 to 120 of about 23,536 (264)

Top 10 NNRTI-RAMs found in patients who failed either the NVP- or EFV-based regimen.

, 2016
Top 10 NNRTI-RAMs found in patients who failed either the NVP- or EFV-based regimen.
Anchalee Avihingsanon (340691), Kiat Ruxrungtham (247724), Opass Putcharoen (2633791), Suwanna Mekprasan (2633794), Phairote Teeranaipong (2633797), Pirapon June Ohata (2633788), Sunee Sirivichayakul (7870)   +6 more
core   +1 more source

Tight binding NNRTi affect the late stages of HIV-1 replication

, 2005
Tight binding NNRTi affect the late stages of HIV-1 ...
N Sluis-Cremer (13717387), G Tachedjian (13711351), A Figuieiredo (13717384), B de (13706269), Johnson Mak (13082904)   +4 more
core   +1 more source

Design, Synthesis, and Preclinical Evaluations of Novel 4-Substituted 1,5-Diarylanilines as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Drug Candidates

Journal of Medicinal Chemistry, 2012
Twenty-one new 4-substituted diarylaniline compounds (DAANs) (Scheme 2, series 13, 14, and 15) were designed, synthesized, and evaluated against wild-type and drug resistant HIV-1 viral strains.
Lian-Qi Sun, Lei Zhu, Keduo Qian, B. Qin, Li Huang, Chin-Ho Chen, Kuo-Hsiung Lee, Lan Xie   +7 more
semanticscholar   +1 more source

Clearance of NNRTI resistance-associated mutations in the HIV-1 DNA reservoir with or without the presence of M184V mutation

Background Recent studies have shown progress in understanding the evolution of HIV antiretroviral resistance–associated mutations (RAMs) in the reservoir, particularly M184V, but data on non-nucleoside reverse transcriptase (RT ...
Karen Zafilaza, Marc-Antoine Valantin, Sophie Sayon, Luminita Schneider, Marc Wirden, Basma Abdi, Théophile Cocherie, Vincent Calvez, Cathia Soulie, Antoine Faycal, Elisa Teyssou, Valérie Pourcher, Anne-Geneviève Marcelin   +12 more
core   +1 more source

Distribution of NNRTI (etravirine) secondary mutations in 112 specimens collected in Maputo and Beira in 2009.

, 2013
Distribution of NNRTI (etravirine) secondary mutations in 112 specimens collected in Maputo and Beira in 2009.
Harriet Merks (160749), Adolfo Salvador Vubil (439418), Angelo Augusto (439420), James I. Brooks (439423), Mussagy Mahomed (439419), Nédio Jonas Mabunda (439422), Dulce Celina Adolfo Bila (439417), Ilesh Vinodrai Jani (439424), Peter Young (178261), Celina Monteiro Abreu (439421), Amilcar Tanuri (7885)   +10 more
core   +1 more source

Distribution of NRTI (a) and NNRTI (b) resistance-associated mutations detected in the historical genotypic resistance tests of the patients.

, 2015
NNRTI: non nucleoside reverse transcriptase inhibitors, NRTI: nucleoside reverse transcriptase inhibitors.
Benoit Visseaux (288245), Diane Descamps (266281), Gilles Peytavin (317457), Minh Patrick Lê (777286), Charlotte Charpentier (49588), Roland Landman (391389), Patrick Yéni (5664625), Sylvie Lariven (777287), Véronique Joly (301541), Yazdan Yazdanpanah (237840), Bao Phung (777288)   +10 more
core   +1 more source

Surveillance of HIV Transmitted Drug Resistance in Latin America and the Caribbean: A Systematic Review and Meta-Analysis.

PLoS ONE, 2016
BackgroundHIV transmitted drug resistance (TDR) remains at moderate level in Latin America and the Caribbean (LAC). However, different epidemiologic scenarios could influence national and sub-regional TDR levels and trends.Methods and findingsWe ...
Santiago Avila-Rios, Omar Sued, Soo-Yon Rhee, Robert W Shafer, Gustavo Reyes-Teran, Giovanni Ravasi   +5 more
doaj   +1 more source

Dyslipidaemia in HIV-infected women on antiretroviral therapy. Analysis of 922 patients from the Spanish VACH cohort

BMC Women's Health, 2011
Background Information concerning lipid disturbances in HIV-infected women on antiretroviral therapy (ART) is scarce. The objective of the study is to describe the lipid profile in a large cohort of HIV-infected women on contemporary ART and analyse ...
Estrada Vicente, Geijo Paloma, Fuentes-Ferrer Manuel, Alcalde María, Rodrigo María, Galindo María, Muñoz Agustín, Domingo Pere, Ribera Esteve, Cosín Jaime, Viciana Pompeyo, Lozano Fernando, Terrón Alberto, Vergara Antonio, Teira Ramón, Muñoz-Sánchez Josefa, Roca Bernardino, Sánchez Trinitario, López-Aldeguer José, Deig Elisabeth, Vidal Francisco, Pedrol Enric, Castaño-Carracedo Manuel, Puig Teresa, Garrido Myriam, Suárez-Lozano Ignacio   +25 more
doaj   +1 more source

Immunologic and virologic failure after first-line NNRTI-based antiretroviral therapy in Thai HIV-infected children

AIDS Research and Therapy, 2011
BackgroundThere are limited data of immunologic and virologic failure in Asian HIV-infected children using non-nucleoside reverse transcriptase inhibitor (NNRTI)-based highly active antiretroviral therapy (HAART).
T. Bunupuradah, T. Puthanakit, P. Kosalaraksa, S. Kerr, Pitch Boonrak, Wasana Prasitsuebsai, P. Lumbiganon, T. Mengthaisong, Chayapa Phasomsap, C. Pancharoen, K. Ruxrungtham, J. Ananworanich   +11 more
semanticscholar   +1 more source

Activity and molecular modeling of a new small molecule active against NNRTI-resistant HIV-1 mutants

, 2009
In this preliminary study we report the antiviral screening of triazolo[4,5-g]quinoline derivatives (compounds 1–6). 4,9-Dihydrotriazolo[4,5-g]quinoline-1-oxide (1) stood out as a new, small molecule endowed with a selective, promising activity in cell ...
Fermeglia, Maurizio, Pricl, Sabrina, La Colla, Paolo, La Colla P., PRICL S, LA COLLA P, Piras, Sandra, Carta A., Piras S., LACOLLA P, FERMEGLIA M, Loddo R., PIRAS S, Carta, Antonio, Loddo, Roberta, Roberta Loddo, Antonio Carta, Paolo La Colla, Sabrina Pricl, Sandra Piras, Maurizio Fermeglia   +20 more
core   +1 more source