Results 121 to 130 of about 23,536 (264)

Minority HIV-1 Drug Resistance Mutations and the Risk of NNRTI-based Antiretroviral Treatment Failure: A Systematic Review and Pooled Analysis

Journal of the American Medical Association (JAMA), 2011
Context Evidence regarding the impact of minority, or low frequency, HIV-1 drug-resistant variants on the effectiveness of first-line antiretroviral treatment (ART) is conflicting. Objective To evaluate the association of pre-existing HIV-1 minority drug-
Jonathan Z. Li, R. Paredes, H. Ribaudo, E. Svarovskaia, K. Metzner, Michael J Kozal, K. H. Hullsiek, M. Balduin, M. Jakobsen, A. Geretti, R. Thiébaut, L. Ostergaard, B. Masquelier, Jeffrey A. Johnson, Michael D. Miller, Daniel R. Kuritzkes   +15 more
semanticscholar   +1 more source

Drug resistance mutations to NRTI, NNRTI and PI according to the HIV-1 subtypes and resistance profile.

, 2019
Drug resistance mutations to NRTI, NNRTI and PI according to the HIV-1 subtypes and resistance profile.
Marinela Mirandela (8044202), Domingos Jandondo (8044205), Miguel Brito (3585407), Joana Morais (8044211), Carlos S. de Jesus (8044199), José C. Couto-Fernandez (8044208), Cruz S. Sebastião (8044193), Amilcar Tanuri (7885), Zoraima Neto (8044196)   +8 more
core   +1 more source

High Prevalence of Doravirine Resistance in HIV-1-Infected Patients with Virological Failure to an NNRTI-Based Single-Tablet Regimen

Infection and Drug Resistance, 2022
Hung-Chin Tsai,1– 5 I-Tzu Chen,1 Hui-Min Chang,6– 8 Susan Shin-Jung Lee,1,2 Yao-Shen Chen1,2 1Division of Infectious Diseases, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; 2Faculty of Medicine, School of Medicine ...
Tsai HC, Chen IT, Chang HM, Lee SSJ, Chen YS   +4 more
doaj  

Predictors of virologic suppression <400 copies/ml 4–12 months after restarting NNRTI-based ART.^a

, 2013
aThe analysis included 90 patients who restarted NNRTI-based ART without a protease inhibitor and had at least one viral load measurement in the 4–12 months after re-starting therapy.bAs noted above some patients had the viral load measured by assays ...
Giota Touloumi (71587), Jeffrey A. Johnson (32526), Zoe Fox (434458), Lieven J. Stuyver (249761), Andrew Owen (355644), Clare Booth (255132), Clara Lehmann (364137), Jonathan Lipscomb (32529), John Baxter (231162), Andrew Phillips (201315), Gilda Tachedjian (37210), Anna Maria Geretti (434457)   +11 more
core   +1 more source

Incidence of Severe Hepatotoxicity Related to Antiretroviral Therapy in HIV/HCV Coinfected Patients

AIDS Research and Treatment, 2010
Introduction. Hepatotoxicity is a concern in HIV/hepatitis C virus (HCV) coinfected patients due to their underlying liver disease. This study assessed the incidence of hepatotoxicity in HIV/HCV co-infected patients in two outpatient infectious diseases ...
Emily L. Heil, Mary L. Townsend, Kenneth Shipp, Amy Clarke, Melissa D. Johnson   +4 more
doaj   +1 more source

Resistance patterns with non-nucleoside reverse transcriptase inhibitor mutations (NNRTI) analyzed on the Stanford database (n = 41).

, 2019
Resistance patterns with non-nucleoside reverse transcriptase inhibitor mutations (NNRTI) analyzed on the Stanford database (n = 41).
Damian Nota Anong (4911604), Fidelis Cho-Ngwa (191165), Kukwah Anthony Tufon (5518691), Pascal Nji Atanga (7908338), Henry Dilonga Meriki (5518679), Theresa Nkuo-Akenji (471455), Irene Ane Anyangwe (7908341)   +6 more
core   +1 more source

Efficacy of NNRTI-Based Antiretroviral Therapy Initiated During Acute HIV Infection

AIDS (London), 2011
Objective:Characterize responses to non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral treatment (ART) initiated during acute HIV infection (AHI).
C. Gay, Ashley J. Mayo, C. Mfalila, H. Chu, Anna C Barry, J. Kuruc, K. McGee, Melissa G. Kerkau, Joseph Sebastian, S. Fiscus, D. Margolis, C. Hicks, G. Ferrari, J. Eron   +13 more
semanticscholar   +1 more source

Prevalence of HIV-1 drug resistance amongst newly diagnosed HIV-infected infants age 4–8 weeks, enrolled in three nationally representative PMTCT effectiveness surveys, South Africa: 2010, 2011–12 and 2012–13

BMC Infectious Diseases, 2019
Background South Africa (SA) has expanded efforts to reduce mother-to-child transmission of HIV (MTCT) to less than 2% at six weeks after birth and to less than 5% at 18 months postpartum by 2016.
Gillian M. Hunt, Johanna Ledwaba, Anna Salimo, Monalisa Kalimashe, Thu-Ha Dinh, Debra Jackson, Gayle Sherman, Adrian Puren, Nobubelo K. Ngandu, Carl Lombard, Lynn Morris, Ameena Goga   +11 more
doaj   +1 more source

Tight binding NNRTi affect the late stages of HIV-1 replication

, 2006
Tight binding NNRTi affect the late stages of HIV-1 ...
N Sluis-Cremer (13717387), G Tachedjian (13711351), A Figuieiredo (13717384), B de (13706269), Johnson Mak (13082904)   +4 more
core  

Univariate analyses for factors associated with hepatotoxicity after initiation of nNRTI-containing regimens within the first 4 weeks.

, 2017
Univariate analyses for factors associated with hepatotoxicity after initiation of nNRTI-containing regimens within the first 4 weeks.
Chien-Yu Cheng (527602), Yi-Chien Lee (625181), Hsin-Yun Sun (61134), Mao-Song Tsai (523496), De-Yu Lin (3769525), Ning-Chi Wang (511973), Pei-Ying Wu (527605), Chien-Ching Hung (61132), Chun-Eng Liu (295105), Yi-Chieh Lee (813489), Chia-Jui Yang (527603), Shu-Hsing Cheng (450825), Hung-Jen Tang (533197), Shih-Ping Lin (3769528)   +13 more
core   +1 more source