Pretreatment of citrus by-products affects polyphenol recovery:a review [PDF]
, 2018 A large amount of citrus waste is generated annually. This waste is of great economic worth, since it contains high levels of polyphenols, which have attracted scientific interest due to their potent antimicrobial and antiradical activities. Pretreatment
Bowyer, Michael C. +7 more
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Screening the effect of four ultrasound-assisted extraction parameters on hesperidin and phenolic acid content of aqueous citrus pomace extracts [PDF]
, 2018 Polyphenols of citrus by-products, due to their antioxidant and antimicrobial activities, could be valorized by pharmaceutical and food industries, adding a value to the citrus processing companies.
Bowyer, Michael C. +6 more
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The potential for dietary factors to prevent or treat osteoarthritis [PDF]
, 2014 Osteoarthritis (OA) is a degenerative joint disease for which there are no disease-modifying drugs. It is a leading cause of disability in the UK. Increasing age and obesity are both major risk factors for OA and the health and economic burden of this ...
Bao, Yongping +8 more
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Anti‐inflammatory Effects of 4′‐Hydroxy Nobiletin, the Major Metabolite of Nobiletin
The FASEB Journal, 2012 Nobiletin, a citrus flavonoid has been associated with various biological activities including anti‐inflammation. We have found that 4′‐hydroxy nobiletin (4′HN) was a major colonic metabolite in mice fed with nobiletin, and the colonic levels of 4′HN were much higher than those of nobiletin.
XIAN WU +4 more
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The citrus flavone nobiletin reduces pro-inflammatory and pro-labour mediators in fetal membranes and myometrium: implications for preterm birth. [PDF]
PLoS ONE, 2014 Spontaneous preterm birth is the leading cause of infant death and of neurological disabilities in survivors. A significant proportion of spontaneous preterm births are associated with infection.
Carrington J Morwood, Martha Lappas
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Beyond antioxidants: the cellular and molecular interactions of flavonoids and how these underpin their actions on the brain [PDF]
, 2010 The consumption of flavonoid-rich foods and beverages has been suggested to limit the neurodegeneration associated with a variety of neurological disorders and to prevent or reverse normal or abnormal deteriorations in cognitive performance.
Spencer, Jeremy Paul
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Pharmaceutical Biology, 2021 Context The interaction between nobiletin and anemarsaponin BII could affect the pharmacological activity of these two drugs during their combination.
Jie Zhang +3 more
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Foods, 2023 Polymethoxyflavones are flavonoids that are abundant in citrus fruit peels and have beneficial effects on human health. Previous studies have demonstrated that the polymethoxyflavones, namely sudachitin and nobiletin, ameliorate obesity and diabetes in ...
Tomoki Abe +2 more
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Optimizing a sustainable ultrasound assisted extraction method for the recovery of polyphenols from lemon by-products:comparison with hot water and organic solvent extractions [PDF]
, 2018 Response surface methodology (RSM) based on a three-factor and three-level Box–Behnken design was employed for optimizing the aqueous ultrasound-assisted extraction (AUAE) conditions, including extraction time (35–45 min), extraction temperature (45–55 ...
Bowyer, Michael C. +6 more
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Myricetin, the main flavonoid in Syzygium cumini leaf, is a novel inhibitor of platelet thiol isomerases PDI and ERp5 [PDF]
, 2020 Background: Flavonoids have been characterized as a prominent class of compounds to treat thrombotic diseases through the inhibition of thiol isomerases. Syzygium cumini is a flavonoid-rich medicinal plant that contains myricetin and gallic acid.
Ayyanar +45 more
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