Results 161 to 170 of about 9,513,177 (193)

Nocebo response in human models of migraine: A systematic review and meta-analysis of randomized, double-blind, placebo-controlled, two-way crossover trials in migraine without aura and healthy volunteers

Cephalalgia, 2020
Background Human models of migraine have been used for the past 30 years to test putative ‘trigger’ molecules and ascertain whether they induce migraine attacks in humans.
Hashmat Ghanizada, Afrim Iljazi, H. Ashina, T. P. Do, Mohammad Al-Mahdi Al-Karagholi, F. Amin, M. Ashina   +6 more
semanticscholar   +1 more source

The Non‐nocebo Response: Can Migraine Medication Efficacy Be Enhanced?

Headache: The Journal of Head and Face Pain, 2003
R. Evans
semanticscholar   +3 more sources

Response to commentaries on sharing online clinical notes with patients: implications for nocebo effects and health equity

Journal of Medical Ethics, 2022
I am grateful for the variety of feedback. Three themes struck me: first, commentators recognised the value of open notes but underlined the importance of exploring unintended consequences of the innovation particularly for already disadvantaged ...
Charlotte Blease
semanticscholar   +1 more source

Nocebo responses in randomized controlled trials of COVID-19 vaccines

Int. Journal of Clinical Pharmacology and Therapeutics, 2022
The aim of this study was to evaluate the frequency and magnitude of nocebo responses in -COVID-19 vaccine trials.We performed a meta-analysis of adverse effects (AEs), severe adverse effects (SAEs), withdrawal due to AEs, death, and immune-mediated SAEs observed in randomized controlled trials (RCTs) of COVID-19 vaccines.Four RCTs with a total of 119 ...
Young Ho, Lee, Gwan Gyu, Song
openaire   +2 more sources

Placebo and Nocebo Responses, Cortisol, and Circulating Beta-Endorphin

Psychosomatic Medicine, 2003
The experiment tested whether the placebo and nocebo responses could be mediated via modulation of stress.Ischemic pain was induced in healthy volunteers (N = 59). When pain reached "7" on a 10-point scale, two groups of subjects received information that a pain relieving (the Placebo group) or a pain increasing (the Nocebo group) substance was ...
Oddmund, Johansen, Jan, Brox, Magne Arve, Flaten   +2 more
openaire   +2 more sources

Placebo and nocebo response magnitude on temporomandibular disorders related-pain: a systematic review and meta-analysis.

Journal of Oral Rehabilitation, 2019
OBJECTIVES The aim of this systematic review (SR) was to answer the following question: "In adult patients with temporomandibular disorders (TMD) related-pain, what is the placebo or nocebo effect of different therapies?" METHODS A SR was performed ...
A. Porporatti, Y. Costa, J. C. Réus, J. Stuginski‐Barbosa, P. Conti, A. Velly, G. De Luca Canto   +6 more
semanticscholar   +1 more source

Mechanisms Involved in Placebo and Nocebo Responses and Implications for Drug Trials

Clinical Pharmacology & Therapeutics, 2011
Drug trials often compare active drugs with inert placebos under double-blind conditions. This standard design is increasingly being questioned in light of recent progress in understanding the mechanisms behind the placebo response.1,2 The growing knowledge of the neurobiology of placebo is forcing us to reconsider the significance of the placebo in ...
Rief, W., Bingel, Ulrike, Schedlowski, Manfred, Enck, P.   +3 more
openaire   +3 more sources

Drug-Related Information Generates Placebo and Nocebo Responses That Modify the Drug Response

Psychosomatic Medicine, 1999
Administration of the muscle relaxant carisoprodol and placebo was crossed with information that was agonistic or antagonistic to the effect of carisoprodol. It was investigated whether information alone induced physiological and psychological responses, and whether information modified the response to the drug.Half of the subjects received capsules ...
M A, Flaten, T, Simonsen, H, Olsen
openaire   +2 more sources

Nocebo response: individual differences, network structure, and heterogeneity

2022
Nocebo effects have been well documented throughout the health and medical literature and are defined as the worsening of symptoms due to prior beliefs, negative-health information or suggestion (Colloca et al., 2020, New England Journal of Medicine).
Cottam, Martha, Terhune, Devin
openaire   +1 more source

Placebo and nocebo responses in painful diabetic neuropathy: systematic review and meta-analysis

Pain, 2023
Abstract This preregistered (CRD42021223379) systematic review and meta-analysis aimed to characterize the placebo and nocebo responses in placebo-controlled randomized clinical trials (RCTs) on painful diabetic neuropathy (PDN), updating the previous literature by a decade. Four databases were searched for PDN trials published in the past 20
Elisa Frisaldi, Jan Vollert, Husam Al Sultani, Fabrizio Benedetti, Aziz Shaibani   +4 more
openaire   +2 more sources