Results 11 to 20 of about 7,926,126 (218)

The placebo response rate and nocebo events in obesity pharmacological trials. A systematic review and meta-analysis

EClinicalMedicine, 2022
Summary: Background: There is a growing number of trials examining the effectiveness of pharmacotherapies for obesity, however, little is known about placebo and nocebo effect in these trials. Hence, we sought to examine the effect of placebo in obesity
Yip Han Chin, Cheng Han Ng, Nicholas WS Chew, Gwyneth Kong, Wen Hui Lim, Darren Jun Hao Tan, Kai En Chan, Ansel Tang, Daniel Q Huang, Mark Y Chan, Gemma Figtree, Jiong-Wei Wang, Asim Shabbir, Chin Meng Khoo, Vincent Wai-Sun Wong, Dan Yock Young, Mohammad Shadab Siddiqui, Mazen Noureddin, Arun Sanyal, David E. Cummings, Nicholas Syn, Mark Dhinesh Muthiah   +21 more
doaj   +3 more sources

Nocebo Effect on Pain-Related Autonomic Responses in a State of Experimentally-Induced Sensitization. [PDF]

Eur J Pain
ABSTRACT Background Enhanced pain‐related autonomic responses were reported after experimentally‐induced secondary mechanical hyperalgesia (SMH) in healthy individuals as well as in a variety of chronic pain cohorts. Stimulus‐induced autonomic responses can also be modulated by positive and negative expectations towards the applied stimulus. This study
Allmendinger F, Rosner J, Egger T, Scheuren PS, Hubli M.   +4 more
europepmc   +3 more sources

Understanding Placebo and Nocebo Responses Based on a Randomized Sham-Controlled Study on Acupuncture in Integrative Cancer Care [PDF]

Integrative Cancer Therapies
Objective: Since placebo and nocebo-responses during acupuncture therapy are rarely studied in clinical contexts, the objective was to investigate placebo and nocebo-responses in a clinical context through comparing positive and negative side-effects ...
Anna Efverman BSP, PhD
doaj   +3 more sources

Brain Network to Placebo and Nocebo Responses in Acute Experimental Lower Back Pain: A Multivariate Granger Causality Analysis of fMRI Data [PDF]

Frontiers in Behavioral Neuroscience, 2021
Background and Objective: Placebo and nocebo responses are widely observed. Herein, we investigated the nocebo hyperalgesia and placebo analgesia responses in brain network in acute lower back pain (ALBP) model using multivariate Granger causality ...
Yu Shi, Shaoye Cui, Yanyan Zeng, Shimin Huang, Guiyuan Cai, Jianming Yang, Wen Wu   +6 more
doaj   +2 more sources

Impairment of Hypnosis by Nocebo Response and Related Neurovegetative Changes: A Case Report in Oral Surgery [PDF]

International Journal of Clinical and Experimental Hypnosis
This article presents the third molar removal in a highly hypnotizable patient, who had been successfully submitted to oral surgery with hypnosis as stand-alone anesthesia in previous sessions.
Luca Queirolo, Enrico Facco, Christian Bacci, Carla Mucignat‐Caretta, Gastone Zanette   +4 more
openalex   +2 more sources

How the number of learning trials affects placebo and nocebo responses [PDF]

Pain, 2010
Conditioning procedures are used in many placebo studies because evidence suggests that conditioning-related placebo responses are usually more robust than those induced by verbal suggestions alone. However, it has not been shown whether there is a causal relation between the number of conditioning trials and the resistance to extinction of placebo and
Luana Colloca, Predrag Petrović, Tor D. Wager, Martin Ingvar, Fabrizio Benedetti   +4 more
openalex   +5 more sources

Nocebo Responses to Antihypertensive Medications [PDF]

The Journal of Clinical Hypertension, 2008
Apatient was seen in consultation for intolerance to multiple antihypertensive medications. She presented a list of her experiences, which is summarized in the Table. Although the cough she experienced while taking angiotensinconverting enzyme inhibitors was a typical side effect of this drug class and consistent on rechallenge, this was not the case ...
Ralph H. Stern
openalex   +5 more sources

New Insights into the Placebo and Nocebo Responses [PDF]

Neuron, 2008
In modern medicine, the placebo response or placebo effect has often been regarded as a nuisance in basic research and particularly in clinical research. The latest scientific evidence has demonstrated, however, that the placebo effect and the nocebo effect, the negative effects of placebo, stem from highly active processes in the brain that are ...
Paul Enck, Fabrizio Benedetti, Manfred Schedlowski   +2 more
openalex   +6 more sources

Nocebo response intensity and influencing factors in the randomized clinical trials of functional dyspepsia: A systematic review and meta‐analysis [PDF]

Journal of Digestive Diseases, 2023
In this study we aimed to evaluate the nocebo response rate in patients with functional dyspepsia (FD) and to explore its influencing factors.
Rui Jie Li, Qingqing Zhang, Yu Feng, Qiao Qiao Pei, Xuan Xuan He, Fu Ping Chen, Dong Ke Wang, Xing Huang Liu, Jin Song Liu, Xiao Hua Hou, Tao Bai   +10 more
openalex   +2 more sources

Incidence and characteristics of the nocebo response from meta‐analyses of the placebo arms of clinical trials of olanzapine for bipolar disorder

Bipolar Disorders, 2018
In the clinical setting, the nocebo phenomenon is where clinical worsening or adverse events occur as a response to a treatment, in a situation in which conditioning from previous treatment exposure and/or expectations of sickness or symptoms lead to ...
Seetal Dodd, Adam J. Walker, Alan Brnabic, Nancy J. Hong, Amber Burns, Michael Berk   +5 more
openalex   +3 more sources