Results 51 to 60 of about 7,926,126 (218)

DISCONTINUATION RATES FOLLOWING A SWITCH FROM A REFERENCE TO A BIOSIMILAR BIOLOGIC IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS [PDF]

Arquivos de Gastroenterologia, 2020
BACKGROUND: Biologics have revolutionized the treatment of inflammatory bowel disease (IBD). However, these drugs had a significant influence on treatment-related costs, which resulted in the development of biosimilars.
Natália Sousa Freitas QUEIROZ, Rogerio SAAD-HOSSNE, Renata de Sá Brito FRÓES, Francisco Guilherme Cancela e PENNA, Stefania Burjack GABRIEL, Adalberta Lima MARTINS, Fabio Vieira TEIXEIRA   +6 more
doaj   +1 more source

Expectation modulates the effect of deep brain stimulation on motor and cognitive function in tremor-dominant Parkinson's disease. [PDF]

PLoS ONE, 2013
Expectation contributes to placebo and nocebo responses in Parkinson's disease (PD). While there is evidence for expectation-induced modulations of bradykinesia, little is known about the impact of expectation on resting tremor. Subthalamic nucleus (STN)
Ariane Keitel, Stefano Ferrea, Martin Südmeyer, Alfons Schnitzler, Lars Wojtecki   +4 more
doaj   +1 more source

The Temporal Modulation of Nocebo Hyperalgesia in a Model of Sustained Pain

Frontiers in Psychiatry, 2022
BackgroundThe direction and the magnitude of verbal suggestions have been shown to be strong modulators of nocebo hyperalgesia, while little attention has been given to the role of their temporal content. Here, we investigate whether temporal suggestions
Eleonora Maria Camerone, Eleonora Maria Camerone, Eleonora Maria Camerone, Simone Battista, Fabrizio Benedetti, Fabrizio Benedetti, Elisa Carlino, Lucia Grazia Sansone, Luca Buzzatti, Luca Buzzatti, Aldo Scafoglieri, Marco Testa, Marco Testa   +12 more
doaj   +1 more source

What Do Placebo and Nocebo Effects Have to Do With Health Equity? The Hidden Toll of Nocebo Effects on Racial and Ethnic Minority Patients in Clinical Care

Frontiers in Psychology, 2021
A placebo effect is a positive clinical response to non-specific elements of treatment with a sham or inert replica of a drug, device, or surgical intervention. There is considerable evidence that placebo effects are driven by expectation of benefit from
Hailey E. Yetman, Nevada Cox, Shelley R. Adler, Kathryn T. Hall, Kathryn T. Hall, Valerie E. Stone, Valerie E. Stone   +6 more
doaj   +1 more source

Qualitative StuNocebo Phenomenon (NP) Involved in Doctor-Patient Communication [PDF]

International Journal of Health Policy and Management, 2014
Background Doctor-patient communication has far reaching influences on the overall well-being of the patients. Words are powerful tools in the doctor’s armamentarium, having both healing as well as harming effects.
Bushra Ashraf, Muhammad Saaiq , Khaleeq Uz-Zaman   +2 more
doaj   +1 more source

Preventing adverse events of chemotherapy for gastrointestinal cancer by educating patients about the nocebo effect: a randomized-controlled trial

BMC Cancer, 2022
Background Adverse events of chemotherapy may be caused by pharmacodynamics or psychological factors such as negative expectations, which constitute nocebo effects. In a randomized controlled trial, we examined whether educating patients about the nocebo
T. Michnevich, Y. Pan, A. Hendi, K. Oechsle, A. Stein, Y. Nestoriuc   +5 more
doaj   +1 more source

Nonmedical Switching From Originators to Biosimilars: Does the Nocebo Effect Explain Treatment Failures and Adverse Events in Rheumatology and Gastroenterology?

Rheumatology and Therapy, 2020
The act of nonmedical switching, defined as switching stable patients who are generally doing well with their current therapy from an originator biologic to its biosimilar, has been endorsed as a reasonable treatment strategy.
Roy Fleischmann, Vipul Jairath, Eduardo Mysler, Dave Nicholls, Paul Declerck   +4 more
doaj   +1 more source

Conditioned Placebo- and Nocebo-Like Effects in Adolescents: The Role of Conscious Awareness, Sensory Discrimination, and Executive Function

Frontiers in Psychiatry, 2020
Background: Conditioning is a key mechanism of placebo and nocebo effects in adults. Little is known about the underlying mechanisms of placebo and nocebo effects in youth and how they might be influenced by conscious awareness and cognitive abilities ...
Regula Neuenschwander, Regula Neuenschwander, Ella Weik, Christine M. Tipper, Karin Jensen, Tim F. Oberlander   +5 more
doaj   +1 more source

"AI enhances our performance, I have no doubt this one will do the same": The Placebo effect is robust to negative descriptions of AI [PDF]

arXiv, 2023
Heightened AI expectations facilitate performance in human-AI interactions through placebo effects. While lowering expectations to control for placebo effects is advisable, overly negative expectations could induce nocebo effects. In a letter discrimination task, we informed participants that an AI would either increase or decrease their performance by
arxiv  

Nocebo in Biosimilars and Generics in Neurology: A Systematic Review

Frontiers in Pharmacology, 2019
Background: Nocebo refers to adverse events related to patients’ negative expectations and previous experiences, mediated by several neurobiological pathways within the brain.
Ioanna Spanou, Theodoros Mavridis, Dimos D. Mitsikostas   +2 more
doaj   +1 more source