Results 131 to 140 of about 70,074 (346)

The proteomic differences and expression of fatty acid‐binding protein 6 (FABP6) associated with gastrointestinal injury in horses with oral administration of a clinical dose of phenylbutazone

Equine Veterinary Journal, EarlyView.
Abstract Background Phenylbutazone (PBZ) can potentially induce gastrointestinal ulceration, and early detection of PBZ‐induced gastroenteropathy will be useful for the diagnosis, treatment, and prevention of PBZ toxicity. Objectives To identify putative proteins associated with equine gastric ulcer syndrome after clinical dose (4.4 mg/kg ...
Ruethaiwan Vinijkumthorn, Nawarus Prapaiwan, Thanapon Chotikaprakal, Phirom Prompiram, Narumon Phaonakrop, Sittiruk Roytrakul, Parichart Tesena   +6 more
wiley   +1 more source

Altered nociception, but not fibromyalgia, after cervical spine injury: Comment on the article by Buskila et al [PDF]

, 1998
Milton Cohen, John Quintner
openalex   +1 more source

Stress exposure in the mdx mouse model of Duchenne muscular dystrophy provokes a widespread metabolic response

The FEBS Journal, EarlyView.
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley   +1 more source

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

The FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický, Sonja Lindfors, Saana Metso, Julia Koivula, Zoltan Szabo, Rasmus Valtonen, Mikko Tulppo, Johanna Magga, Samu Saarimäki, Sonja Bläuer, Ilkka Miinalainen, Risto Kerkelä, Petteri. T. Piepponen, Vootele Voikar, Juho Väänänen, Riikka Kivelä, Bhagwan Yadav, Hanna Lindgren, Pirkko Mattila, Fu‐Ping Zhang, Petra Sipilä, Reetta Hinttala, Satu Kuure   +22 more
wiley   +1 more source

NO‐naproxen modulates inflammation, nociception and downregulates T cell response in rat Freund's adjuvant arthritis [PDF]

, 2000
Carla Cicala, Angela Ianaro, Stefano Fiorucci, Antonio Calignano, Mariarosaria Bucci, Roberto Gerli, Luca Santucci, John L. Wallace, Giuseppe Cirino   +8 more
openalex   +1 more source

Beneficial effect of infiltration around the greater occipital nerve in cluster headache independent of modulation of the nociceptive blink reflex

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives and Background We aimed to explore the effect of greater occipital nerve (GON) infiltration on trigeminal transmission and its relation to clinical response. Infiltration of the GON with a local anesthetic and corticosteroids is effective in the treatment of both episodic (ECH) and chronic cluster headache (CCH).
Willemijn C. Naber, Paulien J. van Tilborg, Martijn R. Tannemaat, Marieke Niesters, Marieke D. Hellinga, Roemer B. Brandt, Rolf Fronczek   +6 more
wiley   +1 more source

Enhanced nociception by exogenous and endogenous substance P given into the spinal cord in mice lacking NR₂A/ε₁, an NMDA receptor subunit [PDF]

, 2000
Makoto Inoue, Masayoshi Mishina, Hiroshi Ueda   +2 more
openalex   +1 more source

Galcanezumab reduces trigeminal nociception and is effective in preclinical models of migraine and trigeminal autonomic cephalalgias

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This study was undertaken to assess the therapeutic efficacy of galcanezumab in preclinical models of migraine and cluster headache and to determine potential shared trigeminovascular mechanisms of action. Galcanezumab is a humanized monoclonal antibody that binds to the neuropeptide calcitonin gene‐related peptide ...
Marta Vila‐Pueyo, Peter J. Goadsby, Kirk W. Johnson, Philip R. Holland   +3 more
wiley   +1 more source

5-HT3-Receptor Antagonist Inhibits Visceral Pain Differently in Chemical and Mechanical Stimuli in Rats

Journal of Pharmacological Sciences, 2004
The present study was designed to compare the effects of a selective 5-HT3-receptor antagonist, alosetron, on the glycerol- and colorectal distention (CRD)-induced visceral nociception as measured by changes in EMG of the external oblique muscle in ...
Tomohisa Mori, Ken-ichi Kawano, Takashi Shishikura   +2 more
doaj  

Animal Consciousness [PDF]

, 2018
This chapter addresses the extent to which nonhuman animals are conscious.
Gennaro, Rocco J.
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