Results 51 to 60 of about 87,919 (361)
TRPV1 activity and substance P release are required for corneal cold nociception [PDF]
Nature Communications, 2019 As a protective mechanism, the cornea is sensitive to noxious stimuli. Here, we show that in mice, a high proportion of corneal TRPM8+ cold-sensing fibers express the heat-sensitive TRPV1 channel.
Guo, Changxiong +6 more
core +3 more sources
INDEX OF ANALGESIA-NOCICEPTION: OPPORTUNITIES AND LIMITS
Вестник анестезиологии и реаниматологии, 2017 The review includes clinical opportunities of the new technique for evaluation balance of nociception/anti-nociception with help of medication of ANI-Monitor (MetroDoloris®, France), used abroad, with the calculation of original index of analgesia ...
A. P. Spasova +2 more
doaj +1 more source
The validity and applications of the analgesia nociception index: a narrative review
Frontiers in Surgery, 2023 Pain refers to the subjective, unpleasant experience that is related to illness or injury. In contrast to pain, nociception refers to the physiological neural processing of noxious stimuli, such as intra-operative surgical stimuli.
Bill Hum +5 more
doaj +1 more source
Do decapod crustaceans have nociceptors for extreme pH? [PDF]
PLoS ONE, 2010 Nociception is the physiological detection of noxious stimuli. Because of its obvious importance, nociception is expected to be widespread across animal taxa and to trigger robust behaviours reliably. Nociception in invertebrates, such as crustaceans, is
Sakshi Puri, Zen Faulkes
doaj +1 more source
Brain oscillations differentially encode noxious stimulus intensity and pain intensity [PDF]
, 2017 Noxious stimuli induce physiological processes which commonly translate into pain. However, under certain conditions, pain intensity can substantially dissociate from stimulus intensity, e.g. during longer-lasting pain in chronic pain syndromes.
Gross, Joachim +7 more
core +1 more source
, 2017 Pain is an integrative phenomenon that results from dynamic interactions between sensory and contextual (i.e., cognitive, emotional, and motivational) processes.
Gross, Joachim +2 more
core +1 more source
, 2016 Experiments of pain with human subjects are difficult, subjective, and ethically constrained. Since the molecular mechanisms of pain transduction are reasonably conserved among different species, these problems are partially solved by the use of animal ...
Leung, Kawai +3 more
core +2 more sources
In vitro and in vivo pharmacological activities of 14-o-phenylpropyloxymorphone, a potent mixed mu/delta/kappa-opioid receptor agonist with reduced constipation in mice [PDF]
, 2018 Pain, particularly chronic pain, is still an unsolved medical condition. Central goals in pain control are to provide analgesia of adequate efficacy and to reduce complications associated with the currently available drugs.
Lattanzi, Roberta +4 more
core +2 more sources
Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes
Cell ReportsSummary: The relationship between transcription and protein expression is complex. We identified polysome-associated RNA transcripts in the somata and central terminals of mouse sensory neurons in control, painful (plus nerve growth factor), and pain ...
M. Ali Bangash +12 more
doaj +1 more source
Genetic study in patients operated dentally and anesthetized with articaine-epinephrine [PDF]
, 2019 Aims: In this study we wanted to figure out if there was a correlation between OPRM1 N40D, TRPV1 I316M, TRPV1 I585V, NOS3 −786T>C and IL6 −174C>G polymorphisms and the response to locally applied articaine-epinephrine anesthetic.
Cieza-Borrella, C +5 more
core +2 more sources