Results 81 to 90 of about 85,874 (280)

Nociception-guided versus Standard Care during Remifentanil–Propofol Anesthesia: A Randomized Controlled Trial

open access: yesAnesthesiology, 2019
What We Already Know about This TopicThe nociception level index (Medasense Biometrics Ltd., Ramat Gan, Israel), is a reliable measure of moderate to intense noxious stimulation during anesthesia and surgery What This Article Tells Us That Is NewIn a ...
Fleur S. Meijer   +8 more
semanticscholar   +1 more source

Disruption of persistent nociceptive behavior in rats with learning impairment. [PDF]

open access: yesPLoS ONE, 2013
Despite the subjective nature of pain experience with cognitive and affective dimensions, preclinical pain research has largely focused on its sensory dimension.
Yuxin Ma   +5 more
doaj   +1 more source

ION CHANNELS OF NOCICEPTION [PDF]

open access: yesAnnual Review of Physiology, 1999
▪ Abstract  Nociceptors are the first cells in the series of neurons that lead to the sensation of pain. The essential functions of nociceptors—transducing noxious stimuli into depolarizations that trigger action potentials, conducting the action potentials from the peripheral sensory site to the synapse in the central nervous system, and converting ...
Michael S. Gold, Edwin W. McCleskey
openaire   +3 more sources

Analgesia Nociception Index for perioperative analgesia monitoring in spinal surgery

open access: yesRevista Brasileira de Anestesiologia
Background and objectives: The Analgesia Nociception Index is an index used to measure the levels of pain, sympathetic system activity and heart rate variability during general anesthesia.
Guldem Turan   +6 more
doaj   +1 more source

Linkage between increased nociception and olfaction via a SCN9A haplotype [PDF]

open access: yes, 2013
Background and Aims: Mutations reducing the function of Nav1.7 sodium channels entail diminished pain perception and olfactory acuity, suggesting a link between nociception and olfaction at ion channel level.
Doehring, Alexandra   +4 more
core   +2 more sources

Quantifying cerebral contributions to pain beyond nociception

open access: yesNature Communications, 2017
Cerebral processes contribute to pain beyond the level of nociceptive input and mediate psychological and behavioural influences. However, cerebral contributions beyond nociception are not yet well characterized, leading to a predominant focus on ...
Choong-Wan Woo   +7 more
semanticscholar   +1 more source

Differential responses of thalamic reticular neurons to nociception in freely behaving mice

open access: yesFrontiers in Behavioral Neuroscience, 2016
Pain serves an important protective role. However, it can also have debilitating adverse effects if dysfunctional, such as in pathological pain conditions.
Yeowool Huh   +3 more
doaj   +1 more source

Multiparameter behavioral profiling reveals distinct thermal response regimes in Caenorhabditis elegans. [PDF]

open access: yes, 2012
BackgroundResponding to noxious stimuli by invoking an appropriate escape response is critical for survival of an organism. The sensations of small and large changes in temperature in most organisms have been studied separately in the context of ...
Ghosh, Rajarshi   +3 more
core   +3 more sources

5-HT3-Receptor Antagonist Inhibits Visceral Pain Differently in Chemical and Mechanical Stimuli in Rats

open access: yesJournal of Pharmacological Sciences, 2004
The present study was designed to compare the effects of a selective 5-HT3-receptor antagonist, alosetron, on the glycerol- and colorectal distention (CRD)-induced visceral nociception as measured by changes in EMG of the external oblique muscle in ...
Tomohisa Mori   +2 more
doaj   +1 more source

Effect of Spinally Administered Simvastatin on the Formalin-Induced Nociceptive Response in Mice

open access: yesJournal of Pharmacological Sciences, 2012
Clinical and experimental observations indicated that 3-hydroxy-3-methylglutaryl CoA reductase inhibitor statins have pleiotropic effects. The present study determined the antinociceptive property of centrally administered simvastatin on the formalin ...
Masahiro Ohsawa   +4 more
doaj   +1 more source

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