Results 221 to 230 of about 341,882 (288)

The oxygen‐sensing FixLJ represses nitrogen fixation in Rhodopseudomonas palustris in response to oxygen

mLife, EarlyView.
Abstract Biological nitrogen fixation in symbiotic diazotrophs is subject to oxygen regulation by an oxygen‐sensing FixLJ two‐component system under micro‐oxic conditions. However, it remains unclear whether this mechanism is conserved in free‐living diazotrophs.
Lingwei Cui, Yan Zeng, Mengmei Wang, Lu Huang, Zheyi Wang, Ying Liu, Yanning Zheng   +6 more
wiley   +1 more source

Non-homologous end joining shapes the genomic rearrangement landscape of chromothripsis from mitotic errors. [PDF]

Nat Commun
Hu Q, Espejo Valle-Inclán J, Dahiya R, Guyer A, Mazzagatti A, Maurais EG, Engel JL, Lu H, Davis AJ, Cortés-Ciriano I, Ly P.   +10 more
europepmc   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

HvarAKR1B1‐mediated tolerance in Hippodamia variegata: Deciphering the metabolic adaptation and fitness costs under prolonged starvation

Pest Management Science, EarlyView.
Starvation stress significantly affected the growth and development of Hippodamia variegata. Combined transcriptome and metabolome analysis and RNA interference verification revealed that HvarAKR1B1 may be involved in the response of Hippodamia variegata to starvation stress.
Bing‐mei Song, De‐qin Hu, Yuan Li, Wang‐quan Jiao, Xiao‐li Ma, Hong‐sheng Pan   +5 more
wiley   +1 more source

Negative feedback loop in the activation of non-homologous end joining DNA repair pathway in Helicobacter pylori infected patients with gastritis. [PDF]

Sci Rep
Amirnorouzi M, Karimi A, Daryani NE, Rajaei A, Hashemi M, Alebouyeh M.   +5 more
europepmc   +1 more source

Resistance of Botrytis cinerea to anilinopyrimidine fungicides: A novel ARMS‐PCR method for the detection of Bcpos5 mutations and characterization of resistance using CRISPR/Cas9 editing

Pest Management Science, EarlyView.
A TETRA‐primer amplification refractory mutation system polymerase chain reaction (T‐ARMS‐PCR) method was developed for simultaneous detection of the L412F/V and G408V mutations. L412F/V mutants were created using the CRISPR/Cas tool and no fitness cost was observed.
Georgios Sofianos, Athanasios Petmezas, Anastasios Samaras, George Karaoglanidis   +3 more
wiley   +1 more source

The Use of Mutational Signatures to Decipher the Inter-Relationship of Reactive Oxygen Species with Homologous Recombination and Non-Homologous End-Joining Deficiencies as Well as Their Effects on APOBEC Mutagenesis in Breast Cancer. [PDF]

Cancers (Basel)
Farmanbar A, Kneller R, Firouzi S.
europepmc   +1 more source

Bt agave: why it is time to explore a new biotechnological frontier

Pest Management Science, EarlyView.
Drylands cover 41% of Earth, requiring sustainable crops. Agave, drought‐ and heat‐adapted, offers high‐value products with low water needs. Pests limit yield, yet Bacillus thuringiensis (Bt) Cry proteins, successful in other plants, remain unexploited in Agave.
Aline Vitória Corim Marim, Marcelo Falsarella Carazzolle, Gonçalo Amarante Guimarães Pereira, Carolina Rossi De Oliveira   +3 more
wiley   +1 more source

Low-dose ionizing radiation-induced RET/PTC1 rearrangement via the non-homologous end joining pathway to drive thyroid cancer. [PDF]

MedComm (2020)
Liu Y, Zhu J, Zhou S, Hou Y, Yan Z, Ao X, Wang P, Zhou L, Chen H, Liang X, Guan H, Gao S, Xie D, Gu Y, Zhou PK.   +14 more
europepmc   +1 more source