Results 131 to 140 of about 18,387,865 (333)
Bulgarian Journal of Veterinary MedicineFoot and Mouth Disease (FMD) is a contagious disease of ruminants that causes significant eco-nomic losses for livestock farmers. It is caused by viruses from the Picornaviridae family, order Picornavirales, and the Aphthovirus genus.
J. Susilo +4 more
doaj +1 more source
A secreted viral non-structural protein determines intestinal norovirus pathogenesis
Cell Host and Microbe, 2019 SUMMARY Murine norovirus (MNoV) infects a low percentage of enteric tuft cells and can persist in these cells for months following acute infection.
Sanghyun Lee +13 more
semanticscholar +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Research on NS1 Proteins of Group 2 Tembusu Virus Inhibiting the Production of Duck Type Ⅰ IFN
Guangdong nongye kexue【Objective】Tembusu virus (TMUV) disease is an important infectious disease in waterfowl. In previous studies, we found that in the early stages of TMUV infection in ducks, the viral copy number of group 2 TMUV in organs such as the liver, kidney, and ...
Yunzhen HUANG +6 more
doaj +1 more source
Cleft analysis of Zika virus non-structural protein 1
Asian Pacific Journal of Tropical Biomedicine, 2017 The non-structural protein 1 is an important molecule of the viruses in flavivirus group including to Zika virus. Recently, the NS1 of Zika virus was discovered.
Somsri Wiwanitkit, Viroj Wiwanitkit
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Characterisation of the flaviviral non-structural protein NS1' [PDF]
, 2015 Members of the genus Flavivirus (including Japanese Encephalitis virus and West Nile virus) are important disease causing agents that result in considerable morbidity and mortality worldwide. NS1' is a C-terminally extended form of the NS1 protein produced only by encephalitic flaviviruses from the Japanese Encephalitis virus serogroup. The function of
openaire +3 more sources
Mutating chikungunya virus non‐structural protein produces potent live‐attenuated vaccine candidate
EMBO Molecular Medicine, 2019 Currently, there are no commercially available live‐attenuated vaccines against chikungunya virus (CHIKV). Here, CHIKVs with mutations in non‐structural proteins (nsPs) were investigated for their suitability as attenuated CHIKV vaccines.
Yi‐Hao Chan +15 more
doaj +1 more source
Rabbit Hemorrhagic Disease Virus Non-structural Protein 6 Induces Apoptosis in Rabbit Kidney Cells
Frontiers in Microbiology, 2019 Rabbit hemorrhagic disease (RHD) is a highly contagious disease caused by rabbit hemorrhagic disease virus (RHDV). Previous research has shown that RHDV induces apoptosis in numerous cell types, although the molecular mechanisms underlying the apoptosis ...
Mengmeng Chen +9 more
semanticscholar +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source