Results 21 to 30 of about 42,828,722 (241)

Non-Contiguous Protein Recombination [PDF]

, 2013
Swapping sequence elements among related proteins can produce chimeric proteins with novel behaviors and improved properties such as enhanced stability. Although homologous mutations are much more conservative than random mutations, chimeras of distantly-
Smith, Matthew Alexander
core   +1 more source

Kinetics of non-structural protein 1, IgM and IgG antibodies in dengue type 1 primary infection [PDF]

Virology Journal, 2011
Abstract Background Early and accurate diagnosis of dengue infection is essential for control of disease outbreaks. Recently, the dengue virus non-structural antigen 1 (NS1), a conserved and secreted glycoprotein, has been used as a marker for early diagnosis of dengue with convenience and cost-effectiveness ...
Wen Kun, Pan Yuxian, Chen Yue, Wang Yadi, Ding Xixia, Di Biao, Hu Dongmei, Wang Ming, Che Xiaoyan   +8 more
openaire   +3 more sources

Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome [PDF]

, 2007
The severe acute respiratory syndrome coronavirus (SARS-CoV) genome is predicted to encode 14 functional open reading frames, leading to the expression of up to 30 structural and non-structural protein products.
Brunn, Albrecht von, Teepe, Carola, Caroline C Friedel, Ralph Baric, Haas, Jürgen, von Brunn, Albrecht, Simpson Jeremy C., Jeremy C. Simpson, Simpson, Jeremy C., Ralf Zimmer, Roberts, Rhonda, Carola Teepe, Rainer Pepperkok, Baric Ralph, Haas Jürgen, Simpson, Jeremy, Zimmer, Ralf, Zimmer Ralf, Caroline C. Friedel, Friedel, Caroline C., Haas, Juergen, Teepe Carola, Albrecht von Brunn, Rhonda Roberts, Jürgen Haas, Friedel Caroline C., Pepperkok Rainer, Pepperkok, Rainer, Roberts Rhonda, Baric, Ralph, Jeremy C Simpson, von Brunn Albrecht   +31 more
core   +1 more source

Cleft analysis of Zika virus non-structural protein 1

Asian Pacific Journal of Tropical Biomedicine, 2017
The non-structural protein 1 is an important molecule of the viruses in flavivirus group including to Zika virus. Recently, the NS1 of Zika virus was discovered. There is still no complete information of the molecular interaction of NS1 of Zika virus which can be the clue for explanation for its pathogenesis and further drug search.
Somsri Wiwanitkit, Viroj Wiwanitkit
openaire   +2 more sources

Design and structural characterisation of olfactomedin-1 variants as tools for functional studies [PDF]

, 2019
Background Olfactomedin-1 (Olfm1; also known as Noelin or Pancortin) is a highly-expressed secreted brain and retina protein and its four isoforms have different roles in nervous system development and function.
Sub Crystal and Structural Chemistry, Van den Hoek, H., Crystal and Structural Chemistry, Janssen, Bert J. C., Pronker, M., Van Den Hoek, Hugo, Janssen, B., Pronker, Matti F.   +7 more
core   +2 more sources

The CATH database: an extended protein family resource for structural and functional genomics [PDF]

, 2003
The CATH database of protein domain structures (http://www.biochem.ucl.ac.uk/bsm/cath_new) currently contains 34 287 domain structures classified into 1383 superfamilies and 3285 sequence families.
Pearl, F.M.G., Martin, Nigel, Bennett, C.F., Harrison, A.P., Sillitoe, I., Shepherd, Adrian J., Thornton, Janet M., Bray, J.E., Orengo, C.A.   +8 more
core   +1 more source

Prediction of Protein Function Using Statistically Significant Sub-Structure Discovery [PDF]

, 2007
Proteins perform a vast number of functional roles. The number of protein structures available for analysis continues to grow and, with the development of methods to predict protein structure directly from genetic sequence without imaging technology, the
Lucas, Craig
core   +7 more sources

Nuclear localization of non-structural protein 1 and nucleocapsid protein of equine arteritis virus

Journal of General Virology, 2002
RNA synthesis (genome replication and subgenomic mRNA transcription) directed by equine arteritis virus (EAV; familyArteriviridae, orderNidovirales) occurs on modified cytoplasmic membranes to which most viral replicase subunits localize. Remarkably, a fraction of non-structural protein 1 (nsp1), a protein essential for transcription but dispensable ...
Marieke A, Tijms, Yvonne, van der Meer, Eric J, Snijder   +2 more
openaire   +2 more sources

Effects of NMR spectral resolution on protein structure calculation [PDF]

, 2013
Adequate digital resolution and signal sensitivity are two critical factors for protein structure determinations by solution NMR spectroscopy. The prime objective for obtaining high digital resolution is to resolve peak overlap, especially in NOESY ...
Victor Jaravine, Peter Güntert (433824), Guntert, P., Tikole, S., Jaravine, Victor, Victor Jaravine (433822), Orekhov, Vladislav,, Orekhov, Vladislav Yu., Jaravine, Victor,, Vladislav Yu. Orekhov (433823), Suhas Tikole (433821), Tikol, Suhas, Suhas Tikole, Vladislav Yu Orekhov, Peter Güntert, Güntert, Peter   +15 more
core   +2 more sources

The Identification of Host Proteins That Interact with Non-Structural Proteins-1α and -1β of Porcine Reproductive and Respiratory Syndrome Virus-1

Viruses, 2023
Porcine reproductive and respiratory syndrome viruses (PRRSV-1 and -2) are the causative agents of one of the most important infectious diseases affecting the global pig industry. Previous studies, largely focused on PRRSV-2, have shown that non-structural protein-1α (NSP1α) and NSP1β modulate host cell responses; however, the underlying molecular ...
Sofia Riccio, Kay Childs, Ben Jackson, Simon P. Graham, Julian Seago   +4 more
openaire   +3 more sources