Results 71 to 80 of about 12,420,554 (248)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

National Breast Screening Committee first report 1998

, 1998
National Breast Screening Committee ...
National Breast Screening Committee
core  

An improved PCR strategy for fast screening of specific and random integrations in rAAV-mediated gene targeted cell clones

BMC Research Notes, 2011
Background Gene targeting by homologous recombination using recombinant adeno-associated virus (rAAV) is becoming a useful tool for basic research and therapeutic applications due to the remarkably high targeting frequency of rAAV virus vectors. However,
Sørensen Charlotte B, Bolund Lars, Luo Yonglun   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Suspect and non-targeted screening of chemical pollutants in Botswana's aquatic environments

Emerging Contaminants
Chemical pollution in the aquatic systems of Botswana has been sparsely studied despite its potential ecological importance. Here, we perform a study of water samples collected from 13 locations distributed across Botswana to obtain the first overview of
Kgato P. Selwe, Charlotte R. Head, Gothatamang N. Phokedi, Jens E.T. Andersen, J. Brett Sallach, Caroline E.H. Dessent   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Report from the 'Eccles' breast screening programme Dublin on epidemiological aspects of screening for breast cancer in Ireland

, 1995
This report outlines the major epidemiological aspects of screening for breast cancer, drawing extensively on experience accrued at the ECCLES Breast Screening Programme over 5 years. It is not an exhaustive account of all aspects of screening.
Codd, Mary B
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The SPORTSMART study: a pilot randomised controlled trial of sexually transmitted infection screening interventions targeting men in football club settings. [PDF]

, 2014
Uptake of chlamydia screening by men in England has been substantially lower than by women. Non-traditional settings such as sports clubs offer opportunities to widen access.
Fuller, SS, Mercer, Catherine H., Hart, Graham, Estcourt, Claudia S., Graham Hart (282426), Fuller, Sebastian S., Lorna J Sutcliffe (16134572), Copas, AJ, Cassell, JA, Roberts, Tracy E, Saunders, John, Mercer, Catherine H, Jackson, Louise J., Muniina, Pamela, Copas, Andrew J, Roberts, Tracy E., Pamela Muniina (16213550), Jackson, LJ, John Saunders (517001), Hart, G, Fuller, Sebastian S, Jackson, Louise J; id_orcid, Johnson, AM, Sebastian S Fuller (16213544), Johnson, Anne, Catherine H Mercer (5777366), Claudia S Estcourt (16134506), Louise J Jackson (16213547), Johnson, Anne M, Cassell, Jackie A, Saunders, J, Andrew J Copas (7463825), Copas, Andrew J., Cassell, Jackie, Estcourt, Claudia S, Sutcliffe, LJ, Roberts, TE, Mercer, CH, Muniina, P, Sutcliffe, Lorna J, Anne Johnson (269123), Jackie Cassell (4460668), Sutcliffe, Lorna, Estcourt, CS, Tracy E Roberts (16135235)   +44 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source