Results 51 to 60 of about 209,431 (210)

MicroRNA Profiling in Paired Left and Right Eyes, Lungs, and Testes of Normal Mice

Molecular Therapy: Nucleic Acids, 2020
Physiological and pathophysiological differences widely exist in paired organ systems. However, the molecular basis for these differences remains largely unknown.
Jiangcheng Shi, Chengqing Hu, Yuan Zhou, Chunmei Cui, Jichun Yang, Qinghua Cui   +5 more
doaj   +1 more source

Integrative analyses of transcriptome sequencing identify novel functional lncRNAs in esophageal squamous cell carcinoma. [PDF]

, 2017
Long non-coding RNAs (lncRNAs) have a critical role in cancer initiation and progression, and thus may mediate oncogenic or tumor suppressing effects, as well as be a new class of cancer therapeutic targets. We performed high-throughput sequencing of RNA
Ai, B, Bai, X-F, Cao, H-H, Feng, C-C, He, J-Z, Huang, G-W, Koeffler, HP, Lei, F, Li, C-Q, Li, E-M, Li, M, Li, S, Li, X, Li, X-C, Liao, L-D, Lin, D-C, Liu, Y-J, Shen, J-H, Tang, Z-D, Wang, L-D, Wang, M-R, Wang, Q-Y, Wang, S-H, Wu, B-L, Wu, J-Y, Wu, Z-Y, Xu, L-Y, Xu, Y-J, Xue, Y-J, Zhang, J, Zhao, J-M, Zheng, C-P, Zhu, Y   +32 more
core   +1 more source

Long noncoding RNA: noncoding and not coded [PDF]

Cell Death Discovery, 2017
Mammalian evolution exhibits extraordinary acceleration in phenotypic complexity while displaying genetic conservation. Indeed, protein-coding genes are 90% identical between mice and human, and the question arises what might be the mechanisms by which phenotypic complexity increases while the number of proteins does not?
Toiber, Debra, Leprivier, Gabriel, Rotblat, Barak   +2 more
openaire   +2 more sources

Identification and Analysis of Human Sex-biased MicroRNAs

Genomics, Proteomics & Bioinformatics, 2018
Sex differences are widely observed under various circumstances ranging from physiological processes to therapeutic responses, and a myriad of sex-biased genes have been identified.
Chunmei Cui, Weili Yang, Jiangcheng Shi, Yong Zhou, Jichun Yang, Qinghua Cui, Yuan Zhou   +6 more
doaj   +1 more source

Computational identification and analysis of noncoding RNAs - Unearthing the buried treasures in the genome [PDF]

, 2007
The central dogma of molecular biology states that the genetic information flows from DNA to RNA to protein. This dogma has exerted a substantial influence on our understanding of the genetic activities in the cells.
Vaidyanathan, P. P., Yoon, Byung-Jun
core  

PVT1: a rising star among oncogenic long non-coding RNAs [PDF]

, 2015
It is becoming increasingly clear that short and long noncoding RNAs critically participate in the regulation of cell growth, differentiation, and (mis)function.
Colombo, Teresa, Farina, Lorenzo, Macino, Giuseppe, Paci, Paola   +3 more
core   +4 more sources

Noncoding RNAs and Stroke [PDF]

The Neuroscientist, 2018
Over many years, extensive efforts have focused on the development and improvement of diagnostic and therapeutic strategies to reduce stroke-associated neurovascular damage, such as blood-brain barrier dysfunction, brain edema, parenchymal inflammation, and neural cell death. However, the only clinically applied pharmacological therapy to date for the
Xuejing Zhang, Milton H. Hamblin, Ke-Jie Yin   +2 more
openaire   +2 more sources

EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs. [PDF]

, 2018
BackgroundPolycomb Repressive Complex 2 (PRC2) catalyzes histone methylation at H3 Lys27, and plays crucial roles during development and diseases in numerous systems.
He, Yuan, Li, Lili, Tang, Lixu, Wang, Yan, Wang, Yibin, Wang, Zhihua, Xie, Yinping, Yu, Ling, Yu, Pengcheng, Zheng, Di   +9 more
core  

Long non-coding RNAs era in liver cancer [PDF]

, 2015
Hepatocellular carcinoma (HCC) is one of the most common malignancies leading to high mortality rates in the general population and the sixth most common cancer worldwide.
Guerrieri, Francesca
core   +1 more source

Noncoding RNAs and cancer

TURKISH JOURNAL OF BIOLOGY, 2014
New and diverse groups of noncoding RNAs are beginning to be discovered. These noncoding RNAs are grouped based on their sizes, genomic positions, or distinctive functions ranging from the regulation of chromatin structure and gene expression to genome stability maintenance. Among noncoding RNAs, microRNAs are the best studied and understood small RNAs
Akman, Hesna Begum, Bensan, Ayse Elif Erson   +1 more
openaire   +2 more sources